Turnover of CD4+ and CD8+ T Lymphocytes in HIV-1 Infection as Measured by Ki-67 Antigen

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Positive Effects of Combined Antiretroviral Therapy on CD4 ⁺ T Cell Homeostasis and Function in Advanced HIV Disease

1997 • 1,812 citations

High Levels of HIV-1 in Plasma During All Stages of Infection Determined By Competitive PCR

1993 • 1,263 citations

The Immunopathogenesis of Human Immunodeficiency Virus Infection

1993 • 1,194 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

1995 • 650 citations

High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors

1995 • 519 citations

Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression.

1996 • 499 citations

CD8 naive T cell counts decrease progressively in HIV-infected adults.

1995 • 495 citations

Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.

1990 • 443 citations

Lymphocyte life-span and memory

1994 • 405 citations

Apoptosis in AIDS

1993 • 375 citations

Cell cycle dependent expression and stability of the nuclear protein detected by Ki‐67 antibody in HL‐60 cells

1992 • 368 citations

Mechanism of Telomerase Induction during T Cell Activation

1996 • 291 citations

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4 ⁺ T Cell Turnover

1996 • 288 citations

In vivo estimates of division and death rates of human T lymphocytes.

1995 • 276 citations

Immunopathogenic Mechanisms in Human Immunodeficiency Virus (HIV) Infection

1991 • 273 citations

T-cell regeneration: all repertoires are not created equal

1997 • 246 citations

Failure of T-cell homeostasis preceding AIDS in HIV-1 infection

1995 • 235 citations

Determination of the growth fraction in cell suspensions by flow cytometry using the monoclonal antibody Ki-67

1986 • 150 citations

Dynamics of HIV-1 and CD4+ lymphocytes in vivo.

1997 • 137 citations

Telomere Length, Telomerase Activity, and Replicative Potential in HIV Infection: Analysis of CD4+ and CD8+T Cells from HIV-discordant Monozygotic Twins

1997 • 131 citations

Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins

1992 • 112 citations

Changes in T and non-T lymphocyte subsets following seroconversion to HIV-1: stable CD3+ and declining CD3- populations suggest regulatory responses linked to loss of CD4 lymphocytes. The Multicenter AIDS Cohort Study.

1993 • 79 citations

Perspectives series: host/pathogen interactions. Dynamics of HIV-1 replication in vivo.

1997 • 77 citations

Molecular characterization of the gene locus of the human cell proliferation‐associated nuclear protein defined by monoclonal antibody Ki‐67

1996 • 72 citations

Rapid turnover of the recirculating lymphocyte pool in vivo

1995 • 55 citations

Molecular characterization of the gene locus of the human cell proliferation-associated nuclear protein defined by monoclonal antibody Ki-67

1996 • 53 citations

Detection of membrane and intracellular antigens by flow cytometry following ORTHO PermeaFix fixation.

1994 • 51 citations

Increased expression of the CD45RO (memory) antigen on T cells in HIV-infected children

1991 • 34 citations

Cell-cycle-associated expressions of proliferating cell nuclear antigen and Ki-67 reactive antigen of bone marrow blast cells in childhood acute leukemia.

1992 • 26 citations

Recent developments in theories of pathogenesis of AIDS

1996 • 7 citations

Kinetic studies on lymphocytes labelled with indium 111‐oxine in patients with chronic lymphocytic leukaemia

1985 • 7 citations

Response : The Age of the Waiho Loop Glacial Event

1996 • 4 citations

Deleted Work

1955 • 0 citations