Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements

Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

1991 • 2,666 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1993 • 1,313 citations

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways

1993 • 1,165 citations

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

1990 • 1,061 citations

Bone and haematopoietic defects in mice lacking c-fos

1992 • 939 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Continuous c-fos expression precedes programmed cell death in vivo

1993 • 784 citations

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1993 • 769 citations

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

1994 • 732 citations

Pleiotropic effects of a null mutation in the c-fos proto-oncogene

1992 • 643 citations

Transcriptional autoregulation of the proto-oncogene fos

1988 • 630 citations

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter.

1990 • 615 citations

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

1989 • 495 citations

The serum response element

1992 • 458 citations

Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF

1991 • 447 citations

Primary culture of identified neurons from the visual cortex of postnatal rats

1986 • 443 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

Isolation of the Cyclosporin-Sensitive T Cell Transcription Factor NFATp

1993 • 415 citations

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.

1988 • 404 citations

Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.

1988 • 391 citations

Functional analysis of a growth factor-responsive transcription factor complex

1993 • 386 citations

Osteoblasts are target cells for transformation in c-fos transgenic mice

1993 • 347 citations

Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction

1989 • 346 citations

c-fos Sequence Necessary for Basal Expression and Induction by Epidermal Growth Factor, 12-O-Tetradecanoyl Phorbol-13-Acetate and the Calcium Ionophore

1987 • 304 citations

Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2.

1992 • 302 citations

Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice.

1990 • 289 citations

A Promoter That Drives Transgene Expression in Cerebellar Purkinje and Retinal Bipolar Neurons

1990 • 282 citations

Proto-oncogene transcription factors and epilepsy

1991 • 252 citations

The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

1988 • 245 citations

Fos-IacZ transgenic mice: Mapping sites of gene induction in the central nervous system

1992 • 237 citations

Multiple sequence elements in the c-fos promoter mediate induction by cAMP.

1989 • 225 citations

Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter.

1989 • 220 citations

Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice.

1993 • 214 citations

The fos Oncogene

1987 • 196 citations

Candidate product of the FBJ murine osteosarcoma virus oncogene: characterization of a 55,000-dalton phosphoprotein

1982 • 181 citations

The Oncogene Handbook

1988 • 181 citations

Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor.

1994 • 179 citations

Characterization of a Pathway for Ciliary Neurotrophic Factor Signaling to the Nucleus

1993 • 177 citations

Inducible binding of a factor to the c-fos regulatory region.

1987 • 168 citations

c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore.

1987 • 126 citations

Ternary complex formation over the c-fos serum response element: p62TCF exhibits dual component specificity with contacts to DNA and an extended structure in the DNA-binding domain of p67SRF.

1992 • 94 citations

Regulation of a fos-lacZ fusion gene: a paradigm for quantitative analysis of stimulus-transcription coupling.

1991 • 92 citations

Differential requirements for cell-specific elastase I enhancer domains in transfected cells and transgenic mice.

1989 • 72 citations

Identification of cis Sequences Controlling Efficient PositionIndependent Tissue-Specific Expression of Human Major Histocompatibility Complex Class I Genes in Transgenic Mice

1991 • 53 citations

Temporal and spatial expression of a fos-lacZ transgene in the developing nervous system

1992 • 39 citations

The AP-1 Site and the cAMP- and Serum Response Elements of the c-fosGene Are Constitutively OccupiedIn Vivo

1991 • 26 citations

Identification of cis sequences controlling efficient position-independent tissue-specific expression of human major histocompatibility complex class I genes in transgenic mice.

1991 • 25 citations