Constitutive expression of inducible nitric oxide synthase in human bronchial epithelial cells induces c-fos and stimulates the cGMP pathway.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.

1993 • 845 citations

Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase

1993 • 825 citations

Nitric Oxide Synthase in Human and Rat Lung: Immunocytochemical and Histochemical Localization

1993 • 825 citations

Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes.

1988 • 781 citations

The nitric oxide and cGMP signal transduction system: regulation and mechanism of action

1993 • 761 citations

Complexes of ^.NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects

1991 • 724 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Interferon‐γ and tumor necrosis factor induce the L‐arginine‐dependent cytotoxic effector mechanism in murine macrophages^*

1988 • 511 citations

Biosynthesis of nitric oxide activates iron regulatory factor in macrophages.

1993 • 409 citations

Feedback inhibition of nitric oxide synthase activity by nitric oxide

1993 • 396 citations

Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway.

1993 • 393 citations

Modulation of Airway Epithelial Cell Ciliary Beat Frequency by Nitric Oxide

1993 • 373 citations

Inhibition of Cytochromes P450 by Nitric Oxide and a Nitric Oxide-Releasing Agent

1993 • 358 citations

Activation of human peripheral blood mononuclear cells by nitric oxide-generating compounds.

1993 • 353 citations

Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells

1993 • 293 citations

Complexes of Nitric Oxide with Nucleophiles as Agents for the Controlled Biological Release of Nitric Oxide

1993 • 231 citations

Mechanism of c-fos induction by active oxygen.

1992 • 224 citations

Clonal growth of epithelial cells from normal adult human bronchus.

1981 • 198 citations

Regulation of nitric oxide synthase by nitric oxide.

1993 • 197 citations

Human bronchial epithelial cells with integrated SV40 virus T antigen genes retain the ability to undergo squamous differentiation

1988 • 188 citations

Human colorectal adenocarcinoma cells: differential nitric oxide synthesis determines their ability to aggregate platelets.

1991 • 182 citations

Islet Cell DNA Is a Target of Inflammatory Attack by Nitric Oxide

1993 • 180 citations

Inhibition of ATP-dependent microsomal Ca2+ sequestration during oxidative stress and its prevention by glutathione.

1983 • 176 citations

Nitric oxide modulation of human leukemia cell differentiation and gene expression

1992 • 172 citations

Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cells via nitric oxide release.

1993 • 137 citations

Atrial natriuretic factor and sodium nitroprusside increase cyclic GMP in cultured rat lung fibroblasts by activating different forms of guanylate cyclase

1987 • 70 citations

Do Cytokines Play a Role in Leukocyte Recruitment and Activation in the Lungs?

1991 • 62 citations

Nitric oxide and superoxide in cultured cells: limited production and influence on DNA synthesis

1993 • 8 citations