Amyloid peptide channels: Blockade by zinc and inhibition by Congo red (amyloid channel block)

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1994 • 1,313 citations

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

1987 • 1,264 citations

Neurotoxicity of a prion protein fragment

1993 • 937 citations

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum.

1993 • 901 citations

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

1994 • 815 citations

A Transmembrane Form of the Prion Protein in Neurodegenerative Disease

1998 • 724 citations

Pore Formation by the Cytotoxic Islet Amyloid Peptide Amylin

1996 • 439 citations

ISLET AMYLOID FORMED FROM DIABETES-ASSOCIATED PEPTIDE MAY BE PATHOGENIC IN TYPE-2 DIABETES

1987 • 342 citations

The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus

1978 • 287 citations

Zn2+ interaction with Alzheimer amyloid beta protein calcium channels.

1996 • 259 citations

Zinc Gluconate Lozenges for Treating the Common Cold

1996 • 227 citations

Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons

1997 • 217 citations

Amyloid β Protein-(1–42) Forms Calcium-permeable, Zn2+-sensitive Channel

1998 • 196 citations

Channel Formation by a Neurotoxic Prion Protein Fragment

1997 • 191 citations

Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium

1995 • 187 citations

Amyloidosis

1994 • 163 citations

Alzheimer amyloid abeta1-42 channels: effects of solvent, pH, and Congo Red.

1999 • 152 citations

Alzheimer amyloid aβ1-42 channels: Effects of solvent, pH, and congo red

1999 • 138 citations

Channel Formation in Planar Lipid Bilayers by a Neurotoxic Fragment of the β-Amyloid Peptide

1994 • 127 citations

The Anti-prion Activity of Congo Red

1998 • 126 citations

Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.

1994 • 100 citations

[35] Use of planar lipid bilayer membranes for rapid screening of membrane active compounds

1999 • 41 citations