Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum.

Alzheimer's Disease: The Amyloid Cascade Hypothesis

1992 • 6,649 citations

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1992 • 1,602 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

1987 • 1,316 citations

In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity

1991 • 833 citations

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1981 • 803 citations

β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1990 • 620 citations

Solution conformations and aggregational properties of synthetic amyloid β-peptides of Alzheimer's disease

1992 • 618 citations

Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease

1991 • 580 citations

CALCIUM CHANNELS: Mechanisms of Selectivity, Permeation, and Block

1987 • 528 citations

Neuritic pathology and dementia in alzheimer's disease

1991 • 362 citations

Advances in Alzheimer's disease

1991 • 358 citations

Correlation between Scores for Dementia and Counts of ‘Senile Plaques’ in Cerebral Grey Matter of Elderly Subjects

1966 • 293 citations

Alzheimer's disease: a cell biological perspective

1992 • 274 citations

Protein chemical and immunocytochemical studies of meningovascular β-amyloid protein in Alzheimer's disease and normal aging

1988 • 173 citations

The pharmacology of tris(hydroxymethyl) aminomethane (THAM).

1962 • 111 citations

Intrinsic anion channel activity of the recombinant first nucleotide binding fold domain of the cystic fibrosis transmembrane regulator protein.

1992 • 53 citations

Chapter 21 Genetics and biology of the Alzheimer amyloid precursor

1990 • 25 citations

Activation of inositol trisphosphate‐sensitive Ca2+ channels of sarcoplasmic reticulum from frog skeletal muscle.

1991 • 24 citations