Expression of p21/waf1 in oral squamous cell carcinomas—correlation with p53 and mdm2 and cellular proliferation index

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

p21 is a universal inhibitor of cyclin kinases

1993 • 3,408 citations

International Histological Classification of Tumours

1981 • 2,045 citations

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

1994 • 2,025 citations

Monoclonal antibodies against recombinant parts of the Ki‐67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave‐processed formalin‐fixed paraffin sections

1992 • 1,484 citations

mdm2 expression is induced by wild type p53 activity.

1993 • 1,286 citations

Inhibition of cyclin-dependent kinases by p21.

1995 • 999 citations

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism.

1995 • 938 citations

Induction of WAF1/CIP1 by a p53-independent pathway.

1994 • 773 citations

p21-containing cyclin kinases exist in both active and inactive states.

1994 • 646 citations

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.

1995 • 593 citations

Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

1994 • 514 citations

Induction of p21 (WAF-1/CIP1) during differentiation.

1994 • 493 citations

Absence of WAF1 mutations in a variety of human malignancies

1994 • 390 citations

Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.

1994 • 272 citations

Altered Patterns of MDM2 and TP53 Expression in Human Bladder Cancer

1994 • 192 citations

Histological typing of oral and oropharyngeal tumours

1971 • 133 citations

P21 RNA and protein expression in non-small cell lung carcinomas: Evidence of p53-independent expression and association with tumoral differentiation

1996 • 132 citations

Aberrant p21CIP1/WAF1 protein accumulation in head-and-neck cancer

1997 • 106 citations

Quantitative Growth Fraction Evaluation with MIB1 and Ki67 Antibodies in Breast Carcinomas

1994 • 90 citations

p21(Waf1/Cipl) and p53 Protein Expression in Breast Cancer

1997 • 84 citations

WAF1/Cip1 gene polymorphism and expression in carcinomas of the breast, ovary, and endometrium.

1997 • 79 citations

p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck

1995 • 74 citations

Mutations and polymorphisms in thep53, p21 andp16 genes in oral carcinomas of Indian betel quid chewers

1996 • 69 citations

p21/WAF1, p53 and PCNA expression andp53 mutation status in hepatocellular carcinoma

1998 • 64 citations

Loss of p21WAF1/CIP1 expression correlates with disease progression in gastric carcinoma

1997 • 59 citations

Differentiation-associated overexpression of the cyclin-dependent kinase inhibitor p21waf-1 in human cutaneous squamous cell carcinoma.

1996 • 46 citations

Functional Expression of Human p21WAF1/CIP1Gene in Rat Glioma Cells Suppresses Tumor Growthin Vivoand Induces Radiosensitivity

1997 • 43 citations

WAF1/Cip1 gene polymorphism and expression in carcinomas of the breast, ovary and endometrium

1996 • 33 citations

18 Differentiation-associated overexpression of the cyclin dependent kinase inhibitor, p21waf-1, in human cutaneous squamous cell carcinoma

1996 • 22 citations

Ionizing Radiation and Teniposide Increase p21^waf1/cip1 and Promote Rb Dephosphorylation but Fail to Suppress E2F Activity in MCF-7 Breast Tumor Cells

1997 • 12 citations