Percutaneous plasma decompression alters cytokine expression in injured porcine intervertebral discs

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue

1986 • 3,282 citations

Rupture of the Intervertebral Disc with Involvement of the Spinal Canal

1934 • 1,883 citations

Multiple control of interleukin-8 gene expression

2002 • 1,034 citations

The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration.

1996 • 985 citations

Chemokines in cutaneous wound healing

2001 • 950 citations

Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators

2002 • 603 citations

Herniated Lumbar Intervertebral Discs Spontaneously Produce Matrix Metalloproteinases, Nitric Oxide, Interleukin-6, and Prostaglandin E2

1996 • 559 citations

Herniated Cervical Intervertebral Discs Spontaneously Produce Matrix Metalloproteinases, Nitric Oxide, Interleukin-6, and Prostaglandin E2

1995 • 544 citations

Inflammatory Cytokines in the Herniated Disc of the Lumbar Spine

1996 • 516 citations

CLINICAL OUTCOMES AFTER LUMBAR DISCECTOMY FOR SCIATICA

2003 • 512 citations

Toward a Biochemical Understanding of Human Intervertebral Disc Degeneration and Herniation

1997 • 389 citations

Tumor Necrosis Factor α and Nucleus-Pulposus-Induced Nerve Root Injury

1998 • 329 citations

2002 SSE Award Competition in Basic Science: Expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption

2002 • 309 citations

Bioactive Interleukin-8 Is Expressed in Wounds and Enhances Wound Healing

2000 • 298 citations

Degeneration and the chemical composition of the human lumbar intervertebral disc

1987 • 281 citations

mRNA Expression of Cytokines and Chemokines in Herniated Lumbar Intervertebral Discs

2002 • 251 citations

Selective Inhibition of Tumor Necrosis Factor-α Prevents Nucleus Pulposus-Induced Thrombus Formation, Intraneural Edema, and Reduction of Nerve Conduction Velocity

2001 • 237 citations

Effects of shear stress on articular chondrocyte metabolism

2000 • 230 citations

Oxygen and Lactate Concentrations Measured in Vivo in the Intervertebral Discs of Patients With Scoliosis and Back Pain

1998 • 226 citations

Biosynthesis of collagen and other matrix proteins by articular cartilage in experimental osteoarthrosis

1980 • 218 citations

The Inflammatory Properties of Contained and Noncontained Lumbar Disc Herniation

1997 • 210 citations

Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy

2002 • 205 citations

Intradiscal Measurements of pH in Patients with Lumbar Rhizopathies

1969 • 196 citations

Cartilage and joint inflammation. Regulation of IL-8 expression by human articular chondrocytes.

1992 • 183 citations

Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage.

1999 • 177 citations

Cytokines in Cartilage Injury and Repair

2001 • 162 citations

Murine Nucleus Pulposus-Derived Cells Secrete Interleukins-1-β, -6, and -10 and Granulocyte-Macrophage Colony-Stimulating Factor in Cell Culture

1997 • 147 citations

Repetitive plasma discharges in saline solutions

2001 • 146 citations

The role of inflammation in disk herniation-associated radiculopathy

1998 • 145 citations

Fibronectin and Its Fragments Increase With Degeneration in the Human Intervertebral Disc

2000 • 144 citations

Comparative Gene Expression Profiling of Normal and Degenerative Discs

2002 • 137 citations

Prostaglandin E2 Content in Herniated Lumbar Disc Disease

1996 • 126 citations

Report of a Controlled Clinical Trial Comparing Automated Percutaneous Lumbar Discectomy and Microdiscectomy in the Treatment of Contained Lumbar Disc Herniation

1995 • 121 citations

A longitudinal study of the matrix changes induced in the intervertebral disc by surgical damage to the annulus fibrosus

1992 • 118 citations

Neuroprotective activity of chemokines against N-methyl-d-aspartate or β-amyloid-induced toxicity in culture

2000 • 117 citations

Effects of Chondroitinase ABC and Chymopapain on Spinal Motion Segment Biomechanics

1997 • 114 citations

Molecular Biology of Degenerative Disc Disease

2000 • 112 citations

Chemokine production by human chondrocytes.

1999 • 112 citations

Spontaneous Production of Monocyte Chemoattractant Protein-1 and Interleukin-8 by the Human Lumbar Intervertebral Disc

2002 • 111 citations

Chymopapain, chemonucleolysis, and nucleus pulposus regeneration.

1983 • 97 citations

Dorsal root sensitivity to interleukin-1 beta, interleukin-6 and tumor necrosis factor in rats

2002 • 93 citations

The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure

2002 • 85 citations

The role of cyclooxygenase-2 and inflammatory cytokines in pain induction of herniated lumbar intervertebral disc.

2000 • 75 citations

Biology of IL‐8‐Induced Stem Cell Mobilization

1999 • 74 citations

1997 Volvo Award Winner in Biomechanical Studies

1997 • 72 citations

Effects of interleukin‐8 on granulation tissue maturation

2002 • 70 citations

Role and Mechanisms of Interleukin-1 in the Modulation of Neurotoxicity

2002 • 69 citations

Hyperalgesia from subcutaneous cytokines

1999 • 68 citations

Collagen Synthesis and Types I, III, IV, and VI Collagens in an Animal Model of Disc Degeneration

1995 • 66 citations

Collagens in the injured porcine intervertebral disc

1994 • 65 citations

THE 9E3/CEF4 GENE PRODUCT IS A CHEMOTACTIC AND ANGIOGENIC FACTOR THAT CAN INITIATE THE WOUND-HEALING CASCADE IN VIVO

1998 • 61 citations

Type‐II collagen gene expression is transiently upregulated in experimentally induced degeneration of rabbit intervertebral disc

1997 • 52 citations

Pro- and Antiinflammatory Cytokine Production After Radiofrequency Ablation of Unresectable Hepatic Tumors

2002 • 51 citations

Humoral Regulation of Blood Flow in the Vertebral Endplate

1994 • 49 citations

An Experimental Study Comparing Percutaneous Discectomy with Chemonucleolysis

1993 • 48 citations

NITRIC OXIDE REGULATION OF INTERLEUKIN-8 GENE EXPRESSION

1997 • 46 citations

Serial Changes Observed by Magnetic Resonance Imaging in the Intervertebral Disc After Chemonucleolysis

1992 • 40 citations

Intervertebral Disc Reconstitution After Chemonucleolysis With Chymopapain is Dependent on Dosage

1996 • 39 citations

The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue.

2002 • 34 citations

Regulation of Expression of Cytokines and Growth Factors in Osteoarthritic Cartilage Explants

2001 • 28 citations

The influence of automated percutaneous lumbar discectomy (APLD) on the biomechanics of the lumbar intervertebral disc. An experimental study.

1992 • 24 citations

Tenascin in the human intervertebral disc: alterations with aging and disc degeneration

2002 • 22 citations

CT-Diskography in Patients with Sciatica

1995 • 15 citations

Characterization of immortalized human chondrocytes originated from osteoarthritis cartilage

2001 • 15 citations

Chymopapain-induced reduction of proinflammatory phospholipase A2 activity and amelioration of neuropathic behavioral changes in an in vivo model of acute sciatica

1997 • 14 citations

CT-Diskography in Patients with Sciatica

1995 • 2 citations