In vivo blockade of gamma interferon affects the influenza virus-induced humoral and the local cellular immune response in lung tissue

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Immune Response in Mice that Lack the Interferon-γ Receptor

1993 • 1,570 citations

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase

1993 • 825 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

Immune interferon: a pleiotropic lymphokine with multiple effects

1985 • 676 citations

Physiological and Molecular Mechanisms of Lymphocyte Homing

1992 • 655 citations

Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon.

1983 • 638 citations

Response of resting human peripheral blood natural killer cells to interleukin 2.

1984 • 616 citations

Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

1991 • 600 citations

CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major.

1994 • 397 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages.

1975 • 314 citations

Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing.

1988 • 302 citations

Antigen presentation by interferon-gamma-treated endothelial cells and fibroblasts: differential ability to function as antigen-presenting cells despite comparable Ia expression.

1985 • 264 citations

Response to influenza infection in mice with a targeted disruption in the interferon gamma gene.

1993 • 247 citations

A kinetic study of immune mediators in the lungs of mice infected with influenza A virus.

1992 • 238 citations

IL-2 and IFN-gamma are two necessary lymphokines in the development of cytolytic T cells.

1989 • 234 citations

T cell regulation of IgG subclass antibody production in response to T-independent antigens.

1981 • 181 citations

Lymphocyte recruitment in delayed-type hypersensitivity. The role of IFN-gamma.

1988 • 170 citations

Induction of IFN-γ in macrophages by lipopolysaccharide

1993 • 165 citations

ELECTROPHORETIC SEPARATION AND PROPERTIES OF MOUSE ANTIHAPTEN ANTIBODIES INVOLVED IN PASSIVE CUTANEOUS ANAPHYLAXIS AND PASSIVE HEMOLYSIS

1964 • 160 citations

Natural killer cells in mouse lung: surface phenotype, target preference, and response to local influenza virus infection.

1983 • 158 citations

Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia.

1993 • 150 citations

Human gamma interferon increases the binding of T lymphocytes to endothelial cells.

1985 • 148 citations

Interferon-gamma regulates an antigen specific for endothelial cells involved in lymphocyte traffic.

1986 • 145 citations

Is BALT a major component of the human lung immune system?

1992 • 145 citations

Concurrent production of interleukin-2, interleukin-10, and gamma interferon in the regional lymph nodes of mice with influenza pneumonia

1994 • 134 citations

IL-1 and IFN-gamma increase vascular permeability.

1988 • 131 citations

Lymphocyte Recruitment to the Lung

1990 • 125 citations

Novel features of the respiratory tract T-cell response to influenza virus infection: lung T cells increase expression of gamma interferon mRNA in vivo and maintain high levels of mRNA expression for interleukin-5 (IL-5) and IL-10

1994 • 99 citations

Frequency analysis of lymphokine-secreting CD4+ and CD8+ T cells activated in a graft-versus-host reaction.

1990 • 90 citations

Intermolecular cooperativity: a clue to why mice have IgG3?

1992 • 89 citations

Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype.

1994 • 86 citations

Mechanism of recovery from acute virus infection. VIII. Treatment of lymphocytic choriomeningitis virus‐infected mice with anti‐interferon‐γ monoclonal antibody blocks generation of virus‐specific cytotoxic T lymphocytes and virus elimination

1989 • 71 citations

Monoclonal antibodies to interferon-gamma inhibit interleukin 2-dependent induction of growth and maturation in lectin/antigen-reactive cytolytic T lymphocyte precursors.

1986 • 61 citations

Cytokine profiles of bronchoalveolar lavage cells from mice with influenza pneumonia: consequences of CD4+ and CD8+ T cell depletion.

1993 • 57 citations

The specificity of the high endothelial venule in bronchus-associated lymphoid tissue (BALT).

1985 • 54 citations

Influenza Virus-specific T Cells Lead to Early Interferon in Lungs of Infected Hosts: Development of a Sensitive Radioimmunoassay

1989 • 28 citations

Destructive Interactions Between Murine Macrophages, Tumor Cells, and Antibodies of the IgG2a Isotype

1985 • 15 citations

Activation of high endothelial venules in peripheral lymph nodes. The involvement of interferon-gamma

1994 • 14 citations