Physiological and Molecular Mechanisms of Lymphocyte Homing

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo.

1991 • 977 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

ELAM-1 is an adhesion molecule for skin-homing T cells

1991 • 843 citations

A tissue-specific endothelial cell molecule involved in lymphocyte homing

1988 • 725 citations

A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family

1989 • 680 citations

Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes.

1988 • 639 citations

The LY‐1B Cell Lineage

1986 • 603 citations

The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140

1991 • 592 citations

A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins

1989 • 568 citations

Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells.

1987 • 554 citations

A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites.

1990 • 512 citations

Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α

1989 • 495 citations

Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium

1990 • 370 citations

Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types.

1989 • 327 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor.

1991 • 307 citations

Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing.

1988 • 302 citations

The Regulation of Lymphocyte Traffic

1986 • 285 citations

Cells and Molecules that Regulate B Lymphopoiesis in Bone Marrow

1989 • 272 citations

T-cell memory: the connection between function, phenotype and migration pathways

1991 • 271 citations

Differential expression of homing-associated adhesion molecules by T cell subsets in man.

1990 • 270 citations

Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.

1989 • 270 citations

Reentry of T cells to the adult thymus is restricted to activated T cells.

1991 • 263 citations

The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes

1989 • 246 citations

Regulation of human B-cell ontogeny

1990 • 238 citations

The preferential accumulation of helper‐inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion

1988 • 230 citations

Flow cytometric assessment of human T-cell differentiation in thymus and bone marrow

1992 • 224 citations

A new surface antigen on intraepithelial lymphocytes in the intestine

1990 • 216 citations

High endothelial differentiation in human lymphoid and inflammatory tissues defined by monoclonal antibody HECA-452.

1988 • 204 citations

The effects of antigen on the migration of recirculating lymphocytes through single lymph nodes.

1976 • 204 citations

Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro

1991 • 178 citations

Cutaneous lymphoid hyperplasia

1969 • 163 citations

The recirculating lymphocyte pool of the rat: a systematic description of the migratory behaviour of recirculating lymphocytes.

1983 • 161 citations

Biased accumulation of T lymphocytes with "memory"-type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lung.

1990 • 159 citations

The influence of afferent lymphatic vessel interruption on vascular addressin expression.

1991 • 154 citations

Phenotypic and functional stages in the intrathymic development of αβ T cells

1991 • 151 citations

Differentiation and functional maturation of bone marrow-derived intestinal epithelial T cells expressing membrane T cell receptor in athymic radiation chimeras.

1990 • 144 citations

THE SPECIFIC SELECTION OF RECIRCULATING LYMPHOCYTES BY ANTIGEN IN NORMAL AND PREIMMUNIZED RATS

1972 • 137 citations

T cell receptor-dependent, antigen-specific stimulation of a murine T cell clone induces a transient, VLA protein-mediated binding to extracellular matrix.

1991 • 125 citations

Differences in in vivo distribution and homing of T cell subsets to mucosal vs nonmucosal lymphoid organs.

1983 • 99 citations

Migration of lymphoblasts to the small intestine

1976 • 99 citations

Selective migration of the human helper‐inducer memory T cell subset: confirmation by in vivo cellular kinetic studies

1991 • 98 citations

Two rare populations of mouse Thy-1lo bone marrow cells repopulate the thymus.

1988 • 98 citations

Rare peripheral T cells migrate to and persist in normal mouse thymus.

1988 • 86 citations

The tissue distribution of T lymphocytes expressing different CD45 polypeptides.

1989 • 83 citations

ESTIMATION OF THE MIGRATION OF THORACIC DUCT LYMPHOCYTES TO NON‐LYMPHOID TISSUES

1977 • 83 citations

Suppression of human lymphocyte chemotaxis and transendothelial migration by anti-LFA-1 antibody.

1989 • 77 citations

Thymus cell migration: cells migrating from thymus to peripheral lymphoid organs have a "mature" phenotype.

1982 • 69 citations

Expression of adhesion structures during B cell development in man.

1989 • 68 citations

Ilal Peyer's patch emigrants are predominantly B cells and travel to all lymphoid tissues in sheep

1991 • 57 citations

Human lymphocyte-high endothelial venule interaction: organ-selective binding of T and B lymphocyte populations to high endothelium.

1986 • 56 citations

A possible route for lymphocyte migration into diseased tissues

1983 • 56 citations

Intraepithelial lymphocytes of the intestinal mucosa: curiouser and curiouser.

1991 • 54 citations

Phenotypic analysis of thymocytes that express homing receptors for peripheral lymph nodes.

1986 • 53 citations

Adherence of Human Helper/Memory T-Cell Subsets To Psoriatic Dermal Endothelium

1990 • 50 citations

Limiting dilution analysis of CD45Rhi and CD45Rlo T cells: Further evidence that CD45Rlo cells are memory cells

1990 • 42 citations

Developmental regulation of vascular addressin expression: a possible role for site-associated environments

1993 • 37 citations

Lymphocyte recruitment in vaccinia virus-induced cutaneous delayed-type hypersensitivity.

1986 • 33 citations

Lamina propria lymphocytes are derived from circulating cells that lack the Leu-8 lymph node homing receptor

1991 • 30 citations

Antibody which defines a subset of bone marrow cells that can migrate to thymus.

1989 • 29 citations

Vascular Addressins: Tissue Selective Endothelial Cell Adhesion Molecules for Lymphocyte Homing

1991 • 20 citations

Traffic of peripheral B and T lymphocytes to hyperplastic, preneoplastic thymuses of AKR mice.

1991 • 13 citations