Destructive Interactions Between Murine Macrophages, Tumor Cells, and Antibodies of the IgG2a Isotype
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Abstract
References (12)
IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells.
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Tumors undergoing rejection induced by monoclonal antibodies of the IgG2a isotype contain increased numbers of macrophages activated for a distinctive form of antibody-dependent cytolysis.
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1981 • 27 citations
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Suppression of Antibody-Sensitized Tumor Cells by Macrophages: Insufficient Supply or Activation of Macrophages within Large Tumors
1979 • 23 citations
Antibody-dependent cytolysis (ADCC) of tumor cells by activated murine macrophages is a two-step process: Quantification of target binding and subsequent target lysis
1984 • 21 citations