IL-1 and IFN-gamma increase vascular permeability.

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1.

1986 • 709 citations

Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2.

1986 • 534 citations

Cytotoxicity of Human p I 7 Interleukin-1 for Pancreatic Islets of Langerhans

1986 • 525 citations

The cell surface receptors for interleukin-1α and interleukin-1β are identical

1986 • 422 citations

Epidermal cell (keratinocyte)-derived thymocyte-activating factor (ETAF).

1981 • 420 citations

Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers.

1986 • 401 citations

Human interleukin 1 is a cytocidal factor for several tumor cell lines.

1985 • 380 citations

Increased superoxide anion release from human endothelial cells in response to cytokines.

1986 • 365 citations

Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy

1986 • 328 citations

Simple Method for Quantitation of Enhanced Vascular Permeability

1970 • 271 citations

Langerhans Cell Production of Interleukin-1

1984 • 233 citations

Interleukin 1 is present in normal human epidermis.

1986 • 214 citations

Acute experimental autoimmune encephalomyelitis in mice

1982 • 207 citations

Interleukin 1 releases histamine from human basophils and mast cells in vitro.

1987 • 181 citations

Human gamma interferon increases the binding of T lymphocytes to endothelial cells.

1985 • 148 citations

In vivo inflammatory activity of epidermal cell-derived thymocyte activating factor and recombinant interleukin 1 in the mouse.

1986 • 130 citations

Human endothelial cell cultures: Phenotypic modulation by leukocyte interleukins

1985 • 128 citations

The role of interleukin-1 in neutrophil leukocyte emigration induced by endotoxin.

1986 • 128 citations

A quantitative method for the study of capillary permeability: Extraction and determination of trypan blue in tissues

1962 • 77 citations

Different mechanisms of release of vasoactive amines by mast cells occur in T cell‐dependent compared to IgE‐dependent cutaneous hypersensitivity responses

1984 • 71 citations

Development of acute autoimmune encephalomyelitis in mice: Factors regulating the effector phase of the disease

1982 • 56 citations

The Role of Langerhans Cells and Keratinocytes in Epidermal Immunity

1986 • 51 citations

Localization of leucocytes in sites of delayed-type hypersensitivity and in lymph nodes: dependence on vasoactive amines.

1982 • 42 citations

Normal epidermis contains high amounts of natural tissue IL 1 biochemical analysis by HPLC identifies a MW approximately 17 Kd form with a P1 5.7 and a MW approximately 30 Kd form.

1986 • 41 citations

ENDOGENEOUS PERMEABILITY FACTORS AND THEIR INHIBITORS AFFECTING VASCULAR PERMEABILITY IN CUTANEOUS ARTHUS REACTIONS AND THERMAL INJURY.

1964 • 40 citations

BC 105 in the prophylaxis of migraine.

1971 • 24 citations

The treatment of migraine with BC 105 (pizotifen): a double blind trial.

1971 • 23 citations

Use of Pizotifen in Severe Migraine: A Long-term Study

1977 • 20 citations

Inhibition of immune-mediated low-dose streptozotocin diabetes by agents which reduce vascular permeability

1986 • 13 citations