In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells.

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1987 • 691 citations

Monoclonal antibodies to mitotic cells.

1983 • 609 citations

Retrograde transport by the microtubule-associated protein MAP 1C

1987 • 547 citations

Distinct populations of microtubules: Tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo

1984 • 532 citations

The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe

1988 • 493 citations

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases

1989 • 486 citations

The NDA3 gene of fission yeast encodes β-tubulin: A cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis

1984 • 473 citations

Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

1984 • 444 citations

Polewards chromosome movement driven by microtubule depolymerization in vitro

1988 • 409 citations

Induction of nuclear envelope breakdown, chromosome condensation, and spindle formation in cell-free extracts.

1985 • 407 citations

Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

1987 • 349 citations

Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis

1986 • 292 citations

Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: uncoordinated mitosis

1986 • 292 citations

Induction of early mitotic events in a cell-free system

1985 • 263 citations

Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery.

1989 • 246 citations

GENETIC MAPPING IN SCHIZOSACCHAROMYCES POMBE BY MITOTIC AND MEIOTIC ANALYSIS AND INDUCED HAPLOIDIZATION

1977 • 246 citations

Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation.

1985 • 239 citations

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

1988 • 220 citations

Identification of the pleiotropic cell division cycle gene NDA2 as one of two different α-tubulin genes in schizosaccharomyces pombe

1984 • 216 citations

Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis.

1988 • 210 citations

A rat monoclonal antibody reacting specifically with the tyrosylated form of alpha-tubulin. I. Biochemical characterization, effects on microtubule polymerization in vitro, and microtubule polymerization and organization in vivo.

1983 • 197 citations

Cell cycle control genes in yeast

1985 • 146 citations

Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding.

1985 • 143 citations

Mitosis in the fission yeast Schizosaccharomyces pombe as revealed by freeze-substitution electron microscopy

1986 • 137 citations

Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosa Ccharomyces Pombe-: Video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a dna-binding fluorescent probe

1981 • 135 citations

Assembly and turnover of detyrosinated tubulin in vivo.

1987 • 123 citations

Distribution of cytoskeletal proteins sharing a conserved phosphorylated epitope.

1986 • 118 citations

Nucleotide requirements for anaphase chromosome movements in permeabilized mitotic cells: Anaphase B but not anaphase a requires ATP

1982 • 103 citations

The diatom spindle in perspective

1978 • 103 citations

Cross-sectional structure of the central mitotic spindle of Diatoma vulgare. Evidence for specific interactions between antiparallel microtubules.

1979 • 98 citations

On the mechanism of anaphase spindle elongation in Diatoma vulgare.

1977 • 97 citations

Differential expressions of essential and nonessential alpha-tubulin genes in Schizosaccharomyces pombe.

1986 • 94 citations

In vitro reactivation of anaphase spindle elongation using isolated diatom spindles

1985 • 93 citations

Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus.

1989 • 84 citations

A fractionated cell-free system for analysis of prophase nuclear disassembly.

1986 • 75 citations

Visualization of chromosomes in mitotically arrested cells of the fission yeast Schizosaccharomyces pombe

1983 • 70 citations

The role of tubulin polymerization during spindle elongation in vitro

1987 • 60 citations

The mechanism of anaphase spindle elongation: uncoupling of tubulin incorporation and microtubule sliding during in vitro spindle reactivation.

1988 • 58 citations

Physiological and ultrastructural analysis of elongating mitotic spindles reactivated in vitro.

1986 • 47 citations

Light and electron microscopic observations on cell division in two large pennate diatoms, Hantzschia and Nitzschia. I. Mitosis in vivo.

1980 • 37 citations

Reactivation of spindle elongation in vitro is correlated with the phosphorylation of a 205 kd spindle-associated protein

1987 • 37 citations

Differential Expressions of Essential and Nonessential α-Tubulin Genes in Schizosaccharomyces Pombe

1986 • 33 citations

In vitro reactivation of anaphase B in isolated spindles of the sea urchin egg

1988 • 30 citations

The mechanism of anaphase spindle elongation

1989 • 29 citations

Distribution of a thiophosphorylated spindle midzone antigen during spindle reactivation in vitro

1989 • 14 citations

Direct observation of mitotic spindle elongation in vitro

1988 • 12 citations