Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

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Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

cdc25+ functions as an inducer in the mitotic control of fission yeast

1986 • 973 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

1979 • 967 citations

Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

1976 • 906 citations

Visualization of Nucleolar Genes

1969 • 865 citations

Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae.

1984 • 838 citations

Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces.

1984 • 827 citations

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1987 • 691 citations

DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

1984 • 685 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

Easy identification of cDNA clones.

1983 • 587 citations

The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe

1988 • 493 citations

Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

1984 • 444 citations

Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA

1987 • 426 citations

A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II.

1985 • 346 citations

One-Step Gene Disruption in Yeast

1989 • 310 citations

Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: uncoordinated mitosis

1986 • 292 citations

Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis

1986 • 292 citations

Construction of a Schizosaccharomyces pombe gene bank in a yeast bacterial shuttle vector and its use to isolate genes by complementation

1982 • 242 citations

Chapter 7 Physiological and Cytological Methods for Schizosaccharomyces pombe

1970 • 238 citations

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

1988 • 220 citations

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

1987 • 208 citations

An electrophoretic karyotype forSchizosaccharomyces pombeby pulsed field gel electrophoresis

1987 • 206 citations

Expression and Characterization of the Human c-myc DNA-Binding Protein

1985 • 205 citations

Homology between RNA polymerases of poxviruses, prokaryotes, and eukaryotes: nucleotide sequence and transcriptional analysis of vaccinia virus genes encoding 147-kDa and 22-kDa subunits.

1986 • 178 citations

Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II.

1985 • 168 citations

Structure of the eukaryotic transcription apparatus: Features of the gene for the largest subunit of Drosophila RNA polymerase II

1985 • 140 citations

The primary structure otE. coliRNA porymerase. Nucleotide sequence of the rpoC gene and amino acid sequence of the β′-sabunit

1982 • 137 citations

Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosa Ccharomyces Pombe-: Video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a dna-binding fluorescent probe

1981 • 135 citations

RPA190, the gene coding for the largest subunit of yeast RNA polymerase A.

1988 • 124 citations

The nucleotide sequence of the fission yeast DNA topoisomerase II gene: structural and functional relationships to other DNA topoisomerases.

1986 • 119 citations

Inhibition of nucleolar reformation after microinjection of antibodies to RNA polymerase I into mitotic cells.

1987 • 110 citations

Subunits of RNA polymerase in function and structure

1974 • 94 citations

Amanitin-resistant RNA polymerase II mutations are in the enzyme's largest subunit.

1983 • 89 citations

Cloning and sequencing ofSchizosaccharomyces pombeDNA topoisomerase I gene, and effect of gene disruption

1987 • 85 citations

A mutation of the B220 subunit gene affects the structural and functional properties of yeast RNA polymerase B in vitro.

1980 • 84 citations

Subunits of RNA polymerase in function and structure

1973 • 71 citations

Visualization of chromosomes in mitotically arrested cells of the fission yeast Schizosaccharomyces pombe

1983 • 70 citations

Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation.

1986 • 68 citations

Triploid meiosis and aneuploidy in Schizosaccharomyces pombe: an unstable aneuploid disomic for chromosome III

1985 • 67 citations

Nudeotide sequence at the end of the gene for the RNA polymerase β subunit (rpoC)

1981 • 60 citations

Mapping of rRNA genes by integration of hybrid plasmids in Schizosaccharomyces pombe

1984 • 57 citations

Genetic studies on the β subunit of Escherichia coli RNA polymerase

1986 • 32 citations

Yeast DNA Topoisomerases and Their Structural Genes

1987 • 30 citations

Molecular Cloning of a Human Gene That Regulates Chromosome Condensation and is Essential for Cell Proliferation

1986 • 30 citations

Deficiency in both type I and type II DNA topoisomerase activities differentially affect rRNA and ribosomal protein synthesis in Schizosaccharomyces pombe

1988 • 27 citations

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