A rat monoclonal antibody reacting specifically with the tyrosylated form of alpha-tubulin. I. Biochemical characterization, effects on microtubule polymerization in vitro, and microtubule polymerization and organization in vivo.

A protein factor essential for microtubule assembly.

1975 • 2,863 citations

The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain

1959 • 2,294 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations

1972 • 1,201 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

1975 • 551 citations

Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitro.

1975 • 535 citations

Control of microtubule assembly-disassembly by calcium-dependent regulator protein.

1978 • 493 citations

Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles.

1981 • 412 citations

Nucleotide and corresponding amino acid sequences encoded by α and β tubulin mRNAs

1981 • 380 citations

Desmin and vimentin coexist at the periphery of the myofibril Z disc

1979 • 327 citations

Cytoplasmic microtubular images in glutaraldehyde-fixed tissue culture cells by electron microscopy and by immunofluorescence microscopy

1978 • 250 citations

Inhibition of microtubule assembly by phosphorylation of microtubule-associated proteins

1980 • 245 citations

Enzyme which specifically adds tyrosine to the α chain of tubulin

1977 • 198 citations

Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth

1977 • 194 citations

Some common properties of the protein that incorporates tyrosine as a single unit and the microtubule proteins

1974 • 176 citations

Preferential action of a brain detyrosinolating carboxypeptidase on polymerized tubulin.

1981 • 173 citations

Modification of tubulin by tyrosylation in cells and extracts and its effect on assembly in vitro.

1977 • 158 citations

Release of tyrosine from tyrosinated tubulin. Some common factors that affect this process and the assembly of tubulin

1977 • 148 citations

Cyclic amp and cell morphology in cultured fibroblasts. Effects on cell shape, microfilament and microtubule distribution, and orientation to substratum.

1975 • 131 citations

Rat Brain Tubulin and Protein Kinase Activity

1974 • 131 citations

A rat monoclonal antibody reacting specifically with the tyrosylated form of alpha-tubulin. II. Effects on cell movement, organization of microtubules, and intermediate filaments, and arrangement of Golgi elements.

1983 • 125 citations

Tubulin requires an accessory protein for self assembly into microtubules

1975 • 110 citations

Tubulinyl‐tyrosine Carboxypeptidase from Chicken Brain: Properties and Partial Purification

1980 • 91 citations

Localization of serum-derived α2 macroglobulin in cultured cells and decrease after moloney sarcoma virus transformation

1977 • 90 citations

Chapter 15 The Cyclic Tyrosination/Detyrosination of Alpha Tubulin

1982 • 77 citations

Protein kinase associated with tubulin: affinity chromatography and properties

1976 • 63 citations

A comparative study of the in vitro polymerization of tubulin in the presence of the microtubule-associated proteins MAP2 and tau.

1981 • 51 citations

Carboxy-terminal amino acid sequence of α-tubulin from porcine brain

1979 • 50 citations

Intact microtubules are required for rapid turnover of carboxyl-terminal tyrosine of alpha-tubulin in cell cultures.

1979 • 49 citations

Different tubulin polymers are produced by microtubule-associated proteins MAP2 and tau in the presence of guanosine 5'-(alpha, beta-methylene)triphosphate.

1980 • 46 citations

Tubulin tyrosylation in vivo and changes accompanying differentiation of cultured neuroblastoma-glioma hybrid cells.

1979 • 43 citations

Ultrastructural localization of tubulin in cultured fibroblasts.

1980 • 24 citations

Chapter 16 Tubulin-Tyrosine Ligase from Brain

1982 • 17 citations

Chapter 17 Preparation of Brain Tyrosinotubulin Carboxypeptidase

1982 • 13 citations