Expression of proliferation and apoptosis-related proteins in usual ductal hyperplasia of the breast

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

1994 • 1,970 citations

Diagnostic Histopathology of the Breast

1988 • 1,083 citations

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer

1997 • 861 citations

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

1992 • 757 citations

The Bcl-2 Protein: a Prognostic Indicator Strongly Related to p53 Protein in Lymph Node-Negative Breast Cancer Patients

1994 • 461 citations

Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer

1992 • 415 citations

Bcl-2 protein expression and long-term survival in breast cancer.

1994 • 404 citations

Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

1995 • 334 citations

A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells.

1994 • 332 citations

A PROSPECTIVE STUDY OF THE DEVELOPMENT OF BREAST CANCER IN 16,692 WOMEN WITH BENIGN BREAST DISEASE

1988 • 328 citations

Loss of Tumor Marker-Immunostaining Intensity on Stored Paraffin Slides of Breast Cancer

1996 • 294 citations

Determination of the prognostic value of cyclin D1 overexpression in breast cancer.

1995 • 215 citations

Cyclin D1 expression in invasive breast cancer. Correlations and prognostic value.

1997 • 207 citations

Oral contraceptive use influences resting breast proliferation

1989 • 207 citations

Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer.

1992 • 194 citations

A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer

1996 • 181 citations

Prognostic significance of TP53 alterations in breast carcinoma

1993 • 171 citations

The use of catalyzed reporter deposition as a means of signal amplification in a variety of formats

1992 • 157 citations

Cyclin D1 protein is overexpressed in hyperplasia and intraductal carcinoma of the breast.

1998 • 146 citations

Ductal carcinoma in situ of the breast. Histologic categorization and its relationship to ploidy and immunohistochemical expression of hormone receptors, p53, and c-erbB-2 protein

1995 • 132 citations

Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

1991 • 124 citations

c-myc, c-erbB-2, and Ki-67 expression in normal breast tissue and in invasive and noninvasive breast carcinoma.

1992 • 123 citations

Immunohistochemical evaluation of c-erbB-2 oncogene expression in ductal carcinoma in situ and atypical ductal hyperplasia of the breast.

1990 • 122 citations

p21WAF1 immunohistochemical expression in breast carcinoma: correlations with clinicopathological data, oestrogen receptor status, MIB1 expression, p53 gene and protein alterations and relapse-free survival

1996 • 121 citations

The neu-protein and breast cancer

1995 • 74 citations

bcl ‐2 expression in the spectrum of preinvasive breast lesions

1996 • 64 citations

bcl-2 expression in the spectrum of preinvasive breast lesions

1996 • 56 citations

p53 protein expression and nuclear DNA content in breast intraductal proliferations

1995 • 54 citations

G1 Cyclins and Control of the Cell Division Cycle in Normal and Transformed Cells

1997 • 42 citations

Expression of p53 protein in benign epithelial hyperplasia, atypical ductal hyperplasia, non-invasive and invasive mammary carcinoma: an immunohistochemical study

1994 • 27 citations

Clinicopathologic analysis of bcl-2 immunostaining in breast carcinoma.

1996 • 26 citations

Expression of c-erb B-2 protein and DNA ploidy in breast carcinogenesis.

1995 • 22 citations