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Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

1995 • 1,834 citations

Risk Factors for Breast Cancer in Women with Proliferative Breast Disease

1985 • 1,817 citations

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1983 • 1,506 citations

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1995 • 1,017 citations

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1994 • 982 citations

D-type cyclins

1995 • 978 citations

Expression and amplification of cyclin genes in human breast cancer.

1993 • 667 citations

Brief, high‐temperature heat denaturation (pressure cooking): A simple and effective method of antigen retrieval for routinely processed tissues

1994 • 479 citations

Genetic errors, cell proliferation, and carcinogenesis.

1991 • 477 citations

Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Association with Cyclin E-Cdk2

1997 • 438 citations

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle.

1994 • 377 citations

Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

1995 • 334 citations

Cyclin D1 and prognosis in human breast cancer

1996 • 318 citations

Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression.

1993 • 295 citations

Loss of Tumor Marker-Immunostaining Intensity on Stored Paraffin Slides of Breast Cancer

1996 • 294 citations

Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

1995 • 268 citations

Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines.

1994 • 260 citations

Determination of the prognostic value of cyclin D1 overexpression in breast cancer.

1995 • 215 citations

Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis.

1995 • 207 citations

The Evaluation of Estrogen Receptor in Primary Breast Carcinoma by Computer-Assisted Image Analysis

1988 • 193 citations

Antiestrogen inhibition of cell cycle progression in breast cancer cells in associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation.

1995 • 179 citations

Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer.

1995 • 166 citations

Genetic divergence in the clonal evolution of breast cancer.

1996 • 164 citations

Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p and 17q.

1995 • 162 citations

Tumours of the Breast

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Cyclin D1 (PRAD1) protein expression in breast cancer: approximately one-third of infiltrating mammary carcinomas show overexpression of the cyclin D1 oncogene.

1995 • 127 citations

Immunohistochemistry of Cyclin D1 in Human Breast Cancer

1994 • 125 citations

Cell cycle‐related variation and tissue‐restricted expression of human cyclin D1 protein

1994 • 121 citations

Molecular genetic studies of early breast cancer evolution

1994 • 120 citations

Estrogen receptor immunohistoohemistry in carcinoma in situ of the breast

1992 • 104 citations

Comparative genomic hybridisation of ductal carcinoma in situ of the breast: identification of regions of DNA amplification and deletion in common with invasive breast carcinoma

1997 • 96 citations

Cyclin D1 and estrogen receptor messenger RNA levels are positively correlated in primary breast cancer.

1996 • 71 citations

High levels of allele loss at the FHIT and ATM genes in non-comedo ductal carcinoma in situ and grade I tubular invasive breast cancers.

1996 • 70 citations

Chromosome 11q13 markers and D-type cyclins in breast cancer

1995 • 69 citations

Characterization of Extensive Genetic Alterations in Ductal Carcinoma In Situ by Fluorescence In Situ Hybridization and Molecular Analysis

1995 • 69 citations

Quantitative Evaluation of the Cell Cycle-Related Retinoblastoma Protein and Localization of Thy-1 Differentiation Protein and Macrophages during Follicular Development and Atresia, and in Human Corpora Lutea1

1995 • 67 citations

The FHIT and PTPRG genes are deleted in benign proliferative breast disease associated with familial breast cancer and cytogenetic rearrangements of chromosome band 3p14.

1996 • 65 citations

Immunohistochemical studies of early breast cancer evolution

1994 • 60 citations

Immunohistochemical studies on oncogene products (c-erbB-2, EGFR, c-myc) and estrogen receptor in benign and malignant breast lesions

1989 • 54 citations

Immunohistochemical study of oncogene product ras p21, c-myc and growth factor EGF in breast carcinomas.

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Benign breast disease: absence of genetic alterations at several loci implicated in breast cancer malignancy.

1995 • 34 citations

TP53 alterations in atypical ductal hyperplasia and ductal carcinomain situ of the breast

1996 • 29 citations