Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer.

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Evaluation of survival data and two new rank order statistics arising in its consideration.

1966 • 7,595 citations

Characterization of a candidate bcl-1 gene.

1991 • 357 citations

The value of morphometry to classic prognosticators in breast cancer

1985 • 335 citations

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.

1987 • 335 citations

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.

1989 • 321 citations

Rearrangement of the chromosome 11 bcl-1 locus in centrocytic lymphoma: analysis with multiple breakpoint probes

1991 • 209 citations

Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors.

1991 • 203 citations

Chromosomal localization of the human proto-oncogene c-ets

1984 • 195 citations

Frequent amplification of the bcl-1 locus in head and neck squamous cell carcinomas.

1989 • 195 citations

Prognosis and Breast Cancer

1991 • 188 citations

Amplification of the int-2 gene in primary human breast tumors.

1988 • 172 citations

High incidence of coamplification of hst-1 and int-2 genes in human esophageal carcinomas.

1989 • 162 citations

Proto-oncogene amplification and human breast tumor phenotype

1990 • 154 citations

Amplification of the int-2 gene in human head and neck squamous cell carcinomas.

1990 • 140 citations

Significance of int-2/hst-1 coamplification as a prognostic factor in patients with esophageal squamous carcinoma.

1991 • 137 citations

Amplification of FGF-related genes in human tumors: possible involvement of HST in breast carcinomas.

1989 • 134 citations

Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

1991 • 124 citations

Prognostic Factors in Breast Cancer

1989 • 78 citations

The human thyroglobulin gene: A polymorphic marker localized distal to C-MYC on chromosome 8 band q24

1985 • 76 citations

Expression of int-2 mRNA in human tumors amplified at the int-2 locus.

1989 • 62 citations

The appropriate breast cancer paradigm.

1987 • 59 citations

Molecular analysis of breaks in BCL-1 proto-oncogene in B-cell lymphomas with abnormalities of 11q13.

1989 • 55 citations

Amplification of the proto-oncogenes int-2, c-erbB-2 and c-myc in human breast cancer

1989 • 48 citations

Analysis of the int-1, int-2, c-myc, and neu oncogenes in human breast carcinomas.

1990 • 47 citations

Feasibility of in situ hybridisation with chromosome specific DNA probes on paraffin wax embedded tissue.

1991 • 46 citations

Pathology and breast screening

1990 • 42 citations

Linkage map of a region of human chromosome band 11q13 amplified in breast and squamous cell tumors

1992 • 42 citations

Prognostic Factors in Breast Cancer

1990 • 24 citations

A human sequence homologous to v-sea maps to chromosome 11, band q13.

1988 • 22 citations

Systemic Adjuvant Therapy for Node-Negative Breast Cancer: Proven or Premature?

1989 • 18 citations