Back to search

Age‐related maculopathy and the impact of blue light hazard

Data up to Jan 2025

Published2006
Citations361
References132

Total Citations Per Year

Abstract

References (132)

Complement Factor H Polymorphism in Age-Related Macular Degeneration

2005 • 4,314 citations

Effects of a Combination of Beta Carotene and Vitamin A on Lung Cancer and Cardiovascular Disease

1996 • 3,608 citations

A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss

2001 • 3,104 citations

Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality

2005 • 2,499 citations

Complement Factor H Polymorphism and Age-Related Macular Degeneration

2005 • 2,387 citations

Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration

2005 • 2,362 citations

The Role of Oxidative Stress in the Pathogenesis of Age-Related Macular Degeneration

2000 • 1,987 citations

A common haplotype in the complement regulatory gene factor H ( HF1/CFH ) predisposes individuals to age-related macular degeneration

2005 • 1,907 citations

The Beaver Dam Eye Study

1992 • 1,362 citations

An Integrated Hypothesis That Considers Drusen as Biomarkers of Immune-Mediated Processes at the RPE-Bruch's Membrane Interface in Aging and Age-Related Macular Degeneration

2001 • 1,256 citations

A role for local inflammation in the formation of drusen in the aging eye

2002 • 1,068 citations

Transmission of the Ocular Media

1962 • 840 citations

Photoreceptor loss in age-related macular degeneration.

1996 • 769 citations

Age-related Macular Degeneration Histopathologic Studies

1993 • 747 citations

B<scp>IOLOGIC</scp> M<scp>ECHANISMS OF THE</scp> P<scp>ROTECTIVE</scp> R<scp>OLE OF</scp> L<scp>UTEIN AND</scp> Z<scp>EAXANTHIN IN THE</scp> E<scp>YE</scp>

2003 • 739 citations

Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor

1996 • 622 citations

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

2003 • 620 citations

Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration

2004 • 616 citations

Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis

2004 • 607 citations

Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells.

1992 • 594 citations

Ocular and optic nerve blood flow at normal and increased intraocular pressures in monkeys (Macaca irus): a study with radioactively labelled microspheres including flow determinations in brain and some other tissues

1973 • 579 citations

Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration

2003 • 537 citations

Smoking and age-related macular degeneration: a review of association

2005 • 523 citations

Increased expression of angiogenic growth factors in age-related maculopathy

1997 • 497 citations

Macrophage Depletion Inhibits Experimental Choroidal Neovascularization

2003 • 488 citations

Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization.

2002 • 432 citations

Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration.

2002 • 424 citations

Aging changes in Bruch's membrane. A histochemical and morphologic study.

1990 • 404 citations

Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects.

2001 • 404 citations

Sunlight and Age-Related Macular Degeneration

1993 • 397 citations

Macrophage Depletion Diminishes Lesion Size and Severity in Experimental Choroidal Neovascularization

2003 • 383 citations

Progression of Age-Related Macular Degeneration

2003 • 383 citations

Potential Public Health Impact of Age-Related Eye Disease Study Results

2003 • 371 citations

Basal Linear Deposit and Large Drusen Are Specific for Early Age-Related Maculopathy

1999 • 363 citations

Progression of Age-Related Macular Degeneration

2005 • 338 citations

Missense Variations in the Fibulin 5 Gene and Age-Related Macular Degeneration

2004 • 320 citations

Age-related Macular Degeneration

2000 • 311 citations

Zinc Supplement Use and Risk of Prostate Cancer

2003 • 309 citations

Retinal photodamage

2001 • 305 citations

Characterization of β amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration

2003 • 303 citations

Aging Changes in Bruch's Membrane

1990 • 294 citations

Histologic analysis of photochemical lesions produced in rhesus retina by short-wave-length light.

1978 • 289 citations

Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin.

2000 • 289 citations

Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE.

2002 • 284 citations

Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration

2000 • 273 citations

Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2.

2001 • 272 citations

Prospective Study of Intake of Fruits, Vegetables, Vitamins, and Carotenoidsand Risk of Age-Related Maculopathy

2004 • 272 citations

Evidence for two apoptotic pathways in light-induced retinal degeneration

2002 • 257 citations

Fundus autofluorescence and age-related macular degeneration

2003 • 252 citations

Histologic and Morphometric Analysis of the Choroid, Bruch's Membrane, and Retinal Pigment Epithelium in Postmortem Eyes With Age-Related Macular Degeneration and Histologic Examination of Surgically Excised Choroidal Neovascular Membranes

1999 • 252 citations

Spare the rods, save the cones in aging and age-related maculopathy.

2000 • 250 citations

Five-year incidence of age-related maculopathy lesions

2002 • 250 citations

Do blue light filters confer protection against age-related macular degeneration?

2004 • 242 citations

Sunlight and the 5-year incidence of early age-related maculopathy: the beaver dam eye study.

2001 • 242 citations

Lipofuscin of Human Retinal Pigment Epithelium

1980 • 236 citations

Blue Light-Induced Singlet Oxygen Generation by Retinal Lipofuscin in Non-Polar Media

1998 • 236 citations

Cataract surgery and the 5-year incidence of late-stage age-related maculopathy

2003 • 228 citations

Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization

2005 • 225 citations

Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching.

2001 • 225 citations

Lipofuscin is a photoinducible free radical generator

1993 • 217 citations

PHOTOPHYSICAL STUDIES ON HUMAN RETINAL LIPOFUSCIN

1995 • 216 citations

Associations of Mortality With Ocular Disorders and an Interventionof High-Dose Antioxidants and Zinc in the Age-Related Eye Disease Study

2004 • 215 citations

Endogenous oxidative stress: relationship to aging, longevity and caloric restriction

2002 • 215 citations

Pathogenesis of lesions in late age-related macular disease

2004 • 209 citations

Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells

2001 • 190 citations

Drusen-Associated Degeneration in the Retina

2003 • 190 citations

Age-related Macular Degeneration after Extracapsular Cataract Extraction with Intraocular Lens Implantation

1996 • 186 citations

The Relationship of Ocular Factors to the Incidence and Progression of Age-Related Maculopathy

1998 • 186 citations

The ageing retina: Physiology or pathology

1987 • 185 citations

The retinal pigment epithelium : function and disease

1998 • 183 citations

Blue light-absorbing intraocular lens and retinal pigment epithelium protection in vitro

2004 • 174 citations

The Retinal Pigment Epithelium: Function and Disease

1999 • 163 citations

Monocyte Activation in Patients With Age-Related Macular Degeneration

2004 • 163 citations

DNA Is a Target of the Photodynamic Effects Elicited in A2E-Laden RPE by Blue-Light Illumination

2003 • 161 citations

Fundus Autofluorescence and Fundus Perimetry in the Junctional Zone of Geographic Atrophy in Patients with Age-Related Macular Degeneration

2004 • 161 citations

Retinal Damage by Visible Light

1967 • 160 citations

Case-control study of the risk factors for age related macular degeneration

1998 • 160 citations

Classification of abnormal fundus autofluorescence patterns in the junctional zone of geographic atrophy in patients with age related macular degeneration

2005 • 160 citations

Retinal light damage: Practical and theoretical considerations

1994 • 156 citations

Neovascular age‐related macular degeneration and its relationship to antioxidant intake

2002 • 139 citations

Differential spectral photic damage to primate cones

1980 • 134 citations

Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium.

2001 • 134 citations

Light-induced Apoptosis: Differential Timing in the Retina and Pigment Epithelium

1997 • 134 citations

Macular pigment and melanin in age-related maculopathy in a general population.

2002 • 131 citations

Aging of Cardiac Myocytes in Culture: Oxidative Stress, Lipofuscin Accumulation, and Mitochondrial Turnover

2004 • 131 citations

How much blue light should an IOL transmit?

2003 • 127 citations

In vivo resonant Raman measurement of macular carotenoid pigments in the young and the aging human retina

2002 • 124 citations

CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION—WHAT IS THE CAUSE?

2003 • 119 citations

Photoreceptor degeneration in albino rats: dependency on age.

1974 • 119 citations

Lipofuscin Accumulation in Cultured Retinal Pigment Epithelial Cells Causes Enhanced Sensitivity to Blue Light Irradiation

1997 • 117 citations

Localization of the site of major resistance to fluid transport in Bruch's membrane.

1997 • 116 citations

Age-dependent variation in metalloproteinase activity of isolated human Bruch's membrane and choroid.

1999 • 116 citations

Macular pigments: their characteristics and putative role

2004 • 113 citations

Contrast Is Enhanced by Yellow Lenses Because of Selective Reduction of Short-Wavelength Light

2000 • 112 citations

Increased prevalence of disciform macular degeneration after cataract extraction with implantation of an intraocular lens.

1994 • 112 citations

Cones Survive Rods in the Light-Damaged Eye of the Albino Rat

1976 • 111 citations

Aging of cultured retinal pigment epithelial cells: oxidative reactions, lipofuscin formation and blue light damage.

2003 • 108 citations

Sunlight and age-related macular degeneration.

2005 • 104 citations

Intraocular Lenses Should Block UV Radiation and Violet but Not Blue Light

2005 • 103 citations

Human macular pigment assessed by imaging fundus reflectometry

1989 • 100 citations

Immunohistochemical characterization of surgically removed subfoveal fibrovascular membranes

1994 • 99 citations

RADIATION AND THE AGEING EYE

1985 • 93 citations

Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes

2002 • 92 citations

Age-Related Changes in the Photoreactivity of Retinal Lipofuscin Granules: Role of Chloroform-Insoluble Components

2004 • 91 citations

Lipofuscin-formation in retinal pigment epithelial cells is reduced by antioxidants

2001 • 89 citations

Macular pigment density and aging, assessed in the normal elderly and those with cataracts and age-related macular degeneration

2004 • 86 citations

Blue light's effects on rhodopsin: photoreversal of bleaching in living rat eyes.

2000 • 83 citations

Routine Vitamin Supplementation To Prevent Cancer and Cardiovascular Disease: Recommendations and Rationale

2003 • 82 citations

Basal Laminar Deposit Formation in APO B100 Transgenic Mice: Complex Interactions between Dietary Fat, Blue Light, and Vitamin E

2003 • 80 citations

Blue light induced apoptosis in rat retina

1999 • 76 citations

Morphologic comparisons between rhodopsin-mediated and short-wavelength classes of retinal light damage.

1992 • 75 citations

Choroidal neovascular membrane inhibition in a laser treated rat model with intraocular sustained release triamcinolone acetonide microimplants

2003 • 75 citations

Involvement of caspase-3 in photoreceptor cell apoptosis induced by in vivo blue light exposure.

2002 • 73 citations

Molecular steps involved in light-induced oxidative damage to retinal rods.

2002 • 71 citations

Age‐related maculopathy: pathogenetic features and new treatment modalities

2002 • 71 citations

A Blue-Blocking Intraocular Lens Should Be Used in Cataract Surgery

2005 • 59 citations

Rod outer segments mediate mitochondrial DNA damage and apoptosis in human retinal pigment epithelium

2001 • 58 citations

Macular pigment density in age-related maculopathy

2004 • 51 citations

Action spectra for the photoconsumption of oxygen by human ocular lipofuscin and lipofuscin extracts

2002 • 47 citations

Ultraviolet radiation absorption of intraocular lenses

2004 • 43 citations

Development of exudative age-related macular degeneration after cataract surgery

1997 • 40 citations

Light Damage Susceptibility and RPE65 in Rats

2002 • 28 citations

Progression of Age-Related Macular Degeneration

2003 • 26 citations

Does Zinc Supplementation Increase the Risk of Prostate Cancer?

2005 • 24 citations

Declines in Arrestin and Rhodopsin in the Macula with Progression of Age-Related Macular Degeneration

2005 • 24 citations

Age-related macular degeneration

2004 • 17 citations

Light effect on the synaptic organ of the rat.

1976 • 16 citations

Clinicopathologic Correlation of Progressive Fibrovascular ProliferationAssociated With Occult Choroidal Neovascularization in Age-Related MacularDegeneration

2004 • 14 citations

Are there advantages in implanting a yellow IOL to reduce the risk of AMD?

2004 • 13 citations

Artificial senescence of bovine retinal pigment epithelial cells induced by near-ultraviolet in vitro

1999 • 12 citations

Light Damage Susceptibility and RPE65 in Rats

2002 • 11 citations

Age-Related Eye Disease Study (AREDS)

2006 • 5 citations

Cited By (0)

Loading...