Trans-inactivation of Receptor Tyrosine Kinases by Novel Angiotensin II AT2 Receptor-interacting Protein, ATIP

Mammalian Ras interacts directly with the serine/threonine kinase raf

1993 • 1,983 citations

G-protein-coupled receptors and signaling networks: emerging paradigms

2001 • 1,005 citations

The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.

1995 • 918 citations

Epidermal growth factor receptors: critical mediators of multiple receptor pathways

1999 • 610 citations

Expression of AT2 receptors in the developing rat fetus.

1991 • 537 citations

WW and SH3 domains, two different scaffolds to recognize proline‐rich ligands

2001 • 474 citations

The Angiotensin II AT2 Receptor Is an AT1Receptor Antagonist

2001 • 459 citations

Homer: a link between neural activity and glutamate receptor function

2000 • 405 citations

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

2001 • 397 citations

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

2001 • 397 citations

Transactivation joins multiple tracks to the ERK/MAPK cascade

2003 • 381 citations

Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking

2001 • 278 citations

G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction

2002 • 263 citations

The ‘magic tail’ of G protein‐coupled receptors: an anchorage for functional protein networks

2003 • 228 citations

Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins

2002 • 227 citations

Angiotensin II type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase

1997 • 225 citations

Signal Transduction from the Angiotensin II AT2 Receptor

2000 • 208 citations

A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy

2003 • 189 citations

Cloning and Characterization of ATRAP, a Novel Protein That Interacts with the Angiotensin II Type 1 Receptor

1999 • 163 citations

Ligand-independent signals from angiotensin II type 2 receptor induce apoptosis

2000 • 137 citations

Regulation of angiotensin II-induced JAK2 tyrosine phosphorylation: roles of SHP-1 and SHP-2

1998 • 136 citations

Functional Significance of Oligomerization of G-protein-coupled Receptors

2000 • 119 citations

Angiotensin and its AT2 receptor: new insights into an old system

2001 • 109 citations

Angiotensin II AT2 receptor subtype

2003 • 104 citations

Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth

1999 • 96 citations

Pivotal role of tyrosine phosphatase SHP-1 in AT2 receptor-mediated apoptosis in rat fetal vascular smooth muscle cell

2001 • 76 citations

ATRAP, Novel AT1 Receptor Associated Protein, Enhances Internalization of AT1 Receptor and Inhibits Vascular Smooth Muscle Cell Growth

2000 • 75 citations

Analysis of Functional Domains of Angiotensin II Type 2 Receptor Involved in Apoptosis

1999 • 71 citations

Functional Trans-inactivation of Insulin Receptor Kinase by Growth-Inhibitory Angiotensin II AT2Receptor

2000 • 64 citations

Angiotensin II AT2 receptors are functionally coupled to protein tyrosine dephosphorylation in N1E-115 neuroblastoma cells

1995 • 60 citations

G_βγ-independent constitutive association of G_αswith SHP-1 and angiotensin II receptor AT₂is essential in AT₂-mediated ITIM-independent activation of SHP-1

2002 • 60 citations

Signaling Mechanism of the AT2 Angiotensin II Receptor: Crosstalk between AT1 and AT2 Receptors in Cell Growth

1999 • 60 citations

Molecular characterization and chromosome localization of a human angiotensin II AT2 receptor gene highly expressed in fetal tissues.

1994 • 58 citations

Angiotensin II Subtype 2 Receptor Activation Inhibits Insulin-Induced Phosphoinositide 3-Kinase and Akt and Induces Apoptosis in PC12W Cells

2002 • 52 citations

Angiotensin II Type 2 Receptor Inhibits Epidermal Growth Factor Receptor Transactivation by Increasing Association of SHP-1 Tyrosine Phosphatase

2001 • 45 citations

Effect of Angiotensin II Type 2 Receptor on Tyrosine Kinase Pyk2 and c-Jun NH2-Terminal Kinase via SHP-1 Tyrosine Phosphatase Activity: Evidence from Vascular-Targeted Transgenic Mice of AT2 Receptor

2001 • 40 citations

Functional cross-talk between angiotensin II and epidermal growth factor receptors in NIH3T3 fibroblasts

2002 • 38 citations

Identification of an interaction between the angiotensin II receptor sub-type AT2 and the ErbB3 receptor, a member of the epidermal growth factor receptor family

2000 • 36 citations

A critical role for PKCζ in endothelin-1-induced uterine contractions at the end of pregnancy

2003 • 36 citations

Role of C‐terminal cytoplasmic domain of the AT2 receptor in ligand binding and signaling

2002 • 21 citations