Immediate Gene Expression Changes After the First Course of Neoadjuvant Chemotherapy in Patients with Primary Breast Cancer Disease

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Molecular portraits of human breast tumours

2000 • 15,445 citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

2001 • 10,602 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

2002 • 6,428 citations

Repeated observation of breast tumor subtypes in independent gene expression data sets

2003 • 5,356 citations

Principles and Applications

1997 • 2,360 citations

Polychemotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.

1998 • 2,199 citations

Effect of preoperative chemotherapy on the outcome of women with operable breast cancer.

1998 • 2,115 citations

Polychemotherapy for early breast cancer: an overview of the randomised trials

1998 • 2,023 citations

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

2003 • 2,013 citations

Estrogen Receptor Status by Immunohistochemistry Is Superior to the Ligand-Binding Assay for Predicting Response to Adjuvant Endocrine Therapy in Breast Cancer

1999 • 1,991 citations

Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18.

1997 • 1,783 citations

Computational analysis of microarray data

2001 • 1,502 citations

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

1999 • 1,410 citations

Predicting the clinical status of human breast cancer by using gene expression profiles

2001 • 1,336 citations

Quantitative Reverse Transcription–Polymerase Chain Reaction to Study mRNA Decay: Comparison of Endpoint and Real-Time Methods

2000 • 1,025 citations

Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer

2003 • 889 citations

Gene expression profiles of human breast cancer progression

2003 • 871 citations

Progesterone Receptor Status Significantly Improves Outcome Prediction Over Estrogen Receptor Status Alone for Adjuvant Endocrine Therapy in Two Large Breast Cancer Databases

2003 • 716 citations

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns.

2001 • 672 citations

Gene expression predictors of breast cancer outcomes

2003 • 631 citations

Primary chemotherapy in operable breast cancer: eight-year experience at the Milan Cancer Institute.

1998 • 581 citations

Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome

2002 • 565 citations

Gene expression profiles of primary breast tumors maintained in distant metastases

2003 • 430 citations

Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

1996 • 416 citations

Prediction of clinical outcome with microarray data: a partial least squares discriminant analysis (PLS-DA) approach.

2003 • 406 citations

Randomized trial of chemoendocrine therapy started before or after surgery for treatment of primary breast cancer.

1995 • 348 citations

A reduction in the requirements for mastectomy in a randomized trial of neoadjuvant chemoendocrine therapy in primary breast cancer

1998 • 322 citations

Estrogen receptor (ER) and progesterone receptor (PgR), by ligand-binding assay compared with ER, PgR and pS2, by immuno-histochemistry in predicting response to tamoxifen in metastatic breast cancer: A Southwest Oncology Group study

2000 • 309 citations

Breast cancer response to neoadjuvant chemotherapy: predictive markers and relation with outcome

2003 • 292 citations

Neoadjuvant chemotherapy in the combined modality approach of locally advanced nonmetastatic breast cancer.

1987 • 263 citations

Multi-class cancer classification via partial least squares with gene expression profiles

2002 • 249 citations

Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors.

2003 • 231 citations

Molecular signature associated with bone marrow micrometastasis in human breast cancer.

2003 • 226 citations

Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer

2002 • 225 citations

Biologic Markers as Predictors of Clinical Outcome From Systemic Therapy for Primary Operable Breast Cancer

1999 • 225 citations

The gene PC3^TIS21/BTG2, prototype member of the PC3/BTG/TOB family: Regulator in control of cell growth, differentiation, and DNA repair?

2001 • 207 citations

Are data from different gene expression microarray platforms comparable?

2004 • 193 citations

High complete remission rates with primary neoadjuvant infusional chemotherapy for large early breast cancer.

1995 • 186 citations

Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells.

2003 • 174 citations

Gene expression profiling of primary breast carcinomas using arrays of candidate genes

2000 • 172 citations

Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma

2000 • 169 citations

cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells

2003 • 165 citations

Role of HER2 in wound-induced breast carcinoma proliferation

2003 • 155 citations

The predictive value of estrogen and progesterone receptors' concentrations on the clinical behavior of breast cancer in women °clinical correlation on 547 patients

1986 • 151 citations

Reduced apoptosis and proliferation and increased Bcl-2 in residual breast cancer following preoperative chemotherapy

1998 • 132 citations

Gene expression profiles of poor-prognosis primary breast cancer correlate with survival

2002 • 131 citations

Dual Function of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Inhibition of Cyclooxygenase and Induction of NSAID-Activated Gene

2002 • 127 citations

Linking gene expression patterns to therapeutic groups in breast cancer.

2000 • 122 citations

Apoptosis in murine tumors treated with chemotherapy agents

1995 • 115 citations

Neoadjuvant chemotherapy for breast carcinoma

2003 • 111 citations

Differential Gene Expression Patterns in HER2/neu-Positive and -Negative Breast Cancer Cell Lines and Tissues

2002 • 107 citations

Identifying Superficial, Muscle-Invasive, and Metastasizing Transitional Cell Carcinoma of the Bladder

2004 • 107 citations

La régression PLS

1998 • 106 citations

Gene expression profiling detects gene amplification and differentiates tumor types in breast cancer.

2003 • 103 citations

Global Transcription Profiling of Estrogen Activity: Estrogen Receptor α Regulates Gene Expression in the Kidney

2003 • 99 citations

Global Gene Expression Changes During Neoadjuvant Chemotherapy for Human Breast Cancer

2002 • 97 citations

Comparing the use of Affymetrix to spotted oligonucleotide microarrays using two retinal pigment epithelium cell lines.

2003 • 84 citations

Associations between gene expressions in breast cancer and patient survival

2002 • 82 citations

Functional role of p21 during the cellular response to stress.

1999 • 81 citations

Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer

2003 • 77 citations

Coordinate expression of apoptosis-associated proteins in human breast cancer before and during chemotherapy.

2002 • 77 citations

Molecular classification of breast cancer patients by gene expression profiling*

2001 • 75 citations

Primary systemic therapy for operable breast cancer - 10-year survival data after chemotherapy and hormone therapy

1997 • 74 citations

The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor gene

2002 • 72 citations

An antisense oligodeoxynucleotide to p21(Waf1/Cip1) causes apoptosis in human breast cancer cells.

2003 • 70 citations

Correlation between HER‐2 expression and response to neoadjuvant chemotherapy with 5‐fluorouracil, doxorubicin, and cyclophosphamide in patients with breast carcinoma

2003 • 66 citations

Induction of apoptosis in murine tumors by cyclophosphamide

1994 • 61 citations

Breast cancer revisited using DNA array‐based gene expression profiling

2002 • 59 citations

Megavariate analysis of hierarchical QSAR data.

2002 • 57 citations

Preoperative Therapy in Breast Cancer: Lessons from the Treatment of Locally Advanced Disease

2002 • 52 citations

Genes that co-cluster with estrogen receptor alpha in microarray analysis of breast biopsies

2001 • 51 citations

Classifying the estrogen receptor status of breast cancers by expression profiles reveals a poor prognosis subpopulation exhibiting high expression of the ERBB2 receptor

2003 • 48 citations

Expression profiling to predict outcome in breast cancer: the influence of sample selection

2002 • 44 citations

Microarrays in primary breast cancer--lessons from chemotherapy studies.

2001 • 39 citations

Prognosis of Breast Cancer and Gene Expression Profiling Using DNA Arrays

2002 • 36 citations

The Expanding Role of Epirubicin in the Treatment of Breast Cancer

2002 • 25 citations

The Prognostic Significance of Steroid Receptor Activity in Tumor Tissues of Patients with Primary Breast Cancer

1997 • 24 citations

Identifying pre-post chemotherapy differences in gene expression in breast tumours: a statistical method appropriate for this aim

2002 • 22 citations

Epirubicin in combination with the taxanes

2001 • 15 citations

Early operable breast cancer

2000 • 5 citations

The molecular biology of mammary intraepithelial neoplasia outgrowths

2003 • 5 citations