Global Transcription Profiling of Estrogen Activity: Estrogen Receptor α Regulates Gene Expression in the Kidney

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

1993 • 1,836 citations

Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

1997 • 1,808 citations

Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule Containing a Novel Immunoglobulin Domain, Is Up-regulated in Renal Cells after Injury

1998 • 1,189 citations

Molecular Determinants for the Tissue Specificity of SERMs

2002 • 1,114 citations

A Prospective, Observational Study of Postmenopausal Hormone Therapy and Primary Prevention of Cardiovascular Disease

2000 • 1,066 citations

The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1

1999 • 1,055 citations

A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease

1997 • 965 citations

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.

1990 • 772 citations

Estrogen receptor (ER) β, a modulator of ERα in the uterus

2000 • 504 citations

Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family

2001 • 487 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.

1995 • 428 citations

Transcriptional activation of genes by 17β-estradiol through estrogen receptor-Sp1 interactions

2001 • 414 citations

Cloning of Human 25-Hydroxyvitamin D-1α-Hydroxylase and Mutations Causing Vitamin D-Dependent Rickets Type 1

1997 • 398 citations

Hormonal Treatment of Postmenopausal Women

1994 • 385 citations

Effects of postmenopausal hormone replacement therapy on lipid, lipoprotein, and apolipoprotein (a) concentrations: analysis of studies published from 1974–2000

2001 • 369 citations

Estrogen Receptor-α Mediates the Protective Effects of Estrogen Against Vascular Injury

2002 • 363 citations

The Effects of Hormone Replacement Therapy and Raloxifene on C-Reactive Protein and Homocysteine in Healthy Postmenopausal Women: A Randomized, Controlled Trial1

2000 • 334 citations

Nonfasting Plasma Total Homocysteine Levels and All-Cause and Cardiovascular Disease Mortality in Elderly Framingham Men and Women

1999 • 334 citations

Use of Hormone Replacement Therapy by Postmenopausal Women in the United States

1999 • 331 citations

Genomic Analysis of Gene Expression in C. elegans

2000 • 300 citations

Conformational Changes and Coactivator Recruitment by Novel Ligands for Estrogen Receptor-α and Estrogen Receptor-β: Correlations with Biological Character and Distinct Differences among SRC Coactivator Family Members*

2000 • 220 citations

Expression and Hormonal Regulation of Coactivator and Corepressor Genes

1998 • 210 citations

The Distribution of Estrogen Receptor-β mRNA in Forebrain Regions of the Estrogen Receptor-α Knockout Mouse

1997 • 207 citations

Sequence Requirements for Estrogen Receptor Binding to Estrogen Response Elements

1998 • 205 citations

Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis

1999 • 200 citations

Site of 1,25(OH)2 vitamin D3 synthesis in the kidney

1978 • 188 citations

Effect of Hormone Replacement Therapy on Bone Mineral Density in Postmenopausal Women with Mild Primary Hyperparathyroidism

1996 • 180 citations

Identification of an Orphan Receptor Gene as a Type 1 Calcitonin Gene-Related Peptide Receptor

1995 • 179 citations

Control of renal vitamin D hydroxylases in birds by sex hormones.

1976 • 176 citations

Engineering of a Mouse for the in Vivo Profiling of Estrogen Receptor Activity

2001 • 176 citations

The AF-1 activation-function of ERα may be dispensable to mediate the effect of estradiol on endothelial NO production in mice

2002 • 171 citations

Laser capture microdissection analysis of gene expression in macrophages from atherosclerotic lesions of apolipoprotein E-deficient mice

2002 • 165 citations

Calcitonin selectively stimulates 25-hydroxyvitamin D3-1α-hydroxylase in proximal straight tubule of rat kidney

1981 • 157 citations

Reciprocal Antagonism Between Estrogen Receptor and NF-κB Activity In Vivo

2001 • 154 citations

The Effects of Hormone Replacement Therapy and Raloxifene on C-Reactive Protein and Homocysteine in Healthy Postmenopausal Women: A Randomized, Controlled Trial

2000 • 141 citations

Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause--a clinical research center study.

1995 • 135 citations

Negative regulation of cytokine signaling: STAT-induced STAT inhibitor

1999 • 128 citations

The postmenopausal estrogen/progestin interventions study: primary outcomes in adherent women

1997 • 125 citations

Evaluation of normalization procedures for oligonucleotide array data based on spiked cRNA controls

2001 • 121 citations

ERAP140, a Conserved Tissue-Specific Nuclear Receptor Coactivator

2002 • 96 citations

Renal and intestinal calcium transport: roles of vitamin D and vitamin D-dependent calcium binding proteins.

1994 • 92 citations

Estrogen-Binding Sites and Their Functional Capacity in Estrogen Receptor Double Knockout Mouse Brain

2002 • 88 citations

Postmenopausal Estrogen Use, Type of Menopause, and Lens Opacities

2001 • 78 citations

Hypertension and pregnancy

1938 • 76 citations

Development of an ER Action Indicator Mouse for the Study of Estrogens, Selective ER Modulators (SERMs), and Xenobiotics

2001 • 73 citations

Complete nucleotide sequence of a putative G protein coupled receptor: RDC1

1990 • 67 citations

Estrogen Receptor α Inhibits IL-1β Induction of Gene Expression in the Mouse Liver

2002 • 66 citations

Homocysteine: a sulph’rous fire

2001 • 57 citations

Isolation of genes identified in mouse renal proximal tubule by comparing different gene expression profiles

1998 • 50 citations

Steroid hormone binding receptors in the rat kidney

1980 • 50 citations

Synthetic estrogen 17alpha-ethinyl estradiol induces pattern of uterine gene expression similar to endogenous estrogen 17beta-estradiol.

1999 • 35 citations

Pregnancy and Steroid Hormones Enhance the Systemic and Regional Hemodynamic Effects of Calcitonin Gene-Related Peptide in Rats1

2001 • 32 citations

Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis

2000 • 28 citations

Identification of a Renal Proximal Tubular Cell-Specific Enhancer in the Mouse 25-Hydroxyvitamin D 1α-Hydroxylase Gene

2002 • 11 citations

Hypertension and Pregnancy

1977 • 8 citations