The Leeuwenhoek Lecture, 1993. Peptide vaccines: dream or reality?

A new type of synthetic peptide library for identifying ligand-binding activity

1991 • 1,769 citations

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.

1984 • 1,467 citations

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

1991 • 1,319 citations

The three-dimensional structure of foot-and-mouth disease virus at 2.9 Å resolution

1989 • 854 citations

Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence

1982 • 826 citations

Baculovirus Expression Vectors: the Requirements for High Level Expression of Proteins, Including Glycoproteins

1987 • 677 citations

Ueber das Zustandekommen der Diphtherie-Immunität und der Tetanus-Immunität bei Thieren

1890 • 607 citations

A synthetic vaccine protects humans against challenge with asexual blood stages of Plasmodium falciparum malaria

1988 • 413 citations

A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

1988 • 384 citations

Construction of Synthetic Immunogen: Use of New T-Helper Epitope on Malaria Circumsporozoite Protein

1987 • 270 citations

Adenovirus-Based Expression Vectors and Recombinant Vaccines

1992 • 252 citations

Non-responsiveness to a foot-and-mouth disease virus peptide overcome by addition of foreign helper T-cell determinants

1987 • 216 citations

Vaccination with SPf66, a chemically synthesised vaccine, against Plasmodium falciparum malaria in Colombia

1993 • 200 citations

Hepatitis B synthetic immunogen comprised of nucleocapsid T-cell sites and an envelope B-cell epitope.

1988 • 141 citations

Microbe Hunters

1926 • 137 citations

New approaches to vaccination against foot-and-mouth disease

1992 • 135 citations

Antiviral effect on MS-2 coliphage obtained with a synthetic antigen.

1976 • 117 citations

Immune response to uncoupled peptides of foot-and-mouth disease virus.

1987 • 101 citations

Diphtheria Toxoid as an Immunising Agent

1923 • 96 citations

A synthetic vaccine constructed by copolymerization of B and T cell determinants

1987 • 96 citations

Engineering of immunogenic peptides by co‐linear synthesis of determinants recognized by B and T cells

1987 • 88 citations

The first field trials of the chemically synthesized malaria vaccine SPf66: safety, immunogenicity and protectivity

1992 • 83 citations

Versuche zur Bestimmung der serologisch determinanten Gruppen des Tabakmosaikvirus

1963 • 66 citations

Foreign epitopes in immunodominant regions of hepatitis B core particles are highly immunogenic and conformationally restricted

1991 • 56 citations

On a new method of producing immunity from contagious diseases

1880 • 40 citations

SYNTHETIC VIRAL VACCINES

1984 • 24 citations

IX. Preliminary note on some points in the pathology of an­thrax, with especial reference to the modification of the properties of the Bacillus anthracis by cultivation, and to the protective influence of inoculation with a modified virus

1880 • 5 citations