IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice

M-1/M-2 Macrophages and the Th1/Th2 Paradigm

2000 • 2,865 citations

Arginine metabolism: nitric oxide and beyond

1998 • 2,697 citations

Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism

1999 • 1,560 citations

Increased Production of Immature Myeloid Cells in Cancer Patients: A Mechanism of Immunosuppression in Cancer

2001 • 1,309 citations

Cd11c+B220+Gr-1+ Cells in Mouse Lymph Nodes and Spleen Display Characteristics of Plasmacytoid Dendritic Cells

2001 • 717 citations

Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages

1997 • 680 citations

Myeloid Suppressor Lines Inhibit T Cell Responses by an NO-Dependent Mechanism

2002 • 657 citations

Alternative Metabolic States in Murine Macrophages Reflected by the Nitric Oxide Synthase/Arginase Balance: Competitive Regulation by CD4+ T Cells Correlates with Th1/Th2 Phenotype

1998 • 640 citations

Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells

1999 • 558 citations

Mechanism of Immune Dysfunction in Cancer Mediated by Immature Gr-1+ Myeloid Cells

2001 • 536 citations

Identification of a CD11b+/Gr-1+/CD31+ myeloid progenitor capable of activating or suppressing CD8+T cells

2000 • 516 citations

Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway

1998 • 473 citations

Unopposed Production of Granulocyte-Macrophage Colony-Stimulating Factor by Tumors Inhibits CD8+ T Cell Responses by Dysregulating Antigen-Presenting Cell Maturation

1999 • 406 citations

Inducible Nitric-oxide Synthase Generates Superoxide from the Reductase Domain

1998 • 389 citations

Helicobacter pyloriarginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival

2001 • 367 citations

Gr-1+ Myeloid Cells Derived from Tumor-Bearing Mice Inhibit Primary T Cell Activation Induced Through CD3/CD28 Costimulation

2000 • 361 citations

Apoptotic Death of CD8+ T Lymphocytes After Immunization: Induction of a Suppressive Population of Mac-1+/Gr-1+ Cells

1998 • 321 citations

Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization

1999 • 311 citations

Peroxynitrite Inhibits T Lymphocyte Activation and Proliferation by Promoting Impairment of Tyrosine Phosphorylation and Peroxynitrite-Driven Apoptotic Death

1999 • 307 citations

Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.

2001 • 289 citations

Tumor-Induced Immune Dysfunctions Caused by Myeloid Suppressor Cells

2001 • 245 citations

Coinduction of Nitric-oxide Synthase and Arginase I in Cultured Rat Peritoneal Macrophages and Rat Tissues in Vivo by Lipopolysaccharide

1997 • 215 citations

Suppression of in vitro cytotoxic response by macrophages due to induced arginase.

1977 • 189 citations

CD11b (Mac-1): a marker for CD8+ cytotoxic T cell activation and memory in virus infection.

1992 • 187 citations

Dendritic Cells Infiltrating Tumors Cotransduced with Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf) and Cd40 Ligand Genes Take up and Present Endogenous Tumor-Associated Antigens, and Prime Naive Mice for a Cytotoxic T Lymphocyte Response

1999 • 184 citations

Nω-Hydroxy-L-Arginine, an Intermediate in the L-Arginine to Nitric Oxide Pathway, Is a Strong Inhibitor of Liver and Macrophage Arginase

1994 • 170 citations

Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection.

1995 • 169 citations

Immortalized Myeloid Suppressor Cells Trigger Apoptosis in Antigen-Activated T Lymphocytes

2000 • 155 citations

Nitric oxide and thiol redox regulation of Janus kinase activity

1998 • 150 citations

Resection of Solid Tumors Reverses T Cell Defects and Restores Protective Immunity

2000 • 146 citations

Role of Ornithine as a Proline Precursor in Healing Wounds

1993 • 101 citations

Transient Host Range Selection for Genetic Engineering of Modified Vaccinia Virus Ankara

2000 • 88 citations

Th1 and Th2 Cell Clones to a Poorly Immunogenic Tumor Antigen Initiate CD8+ T Cell-Dependent Tumor Eradication In Vivo

2000 • 87 citations

Myeloid differentiation treatment to diminish the presence of immune-suppressive CD34+ cells within human head and neck squamous cell carcinomas.

1997 • 86 citations

Identification of a CD11b+/Gr-1+/CD31+ myeloid progenitor capable of activating or suppressing CD8+T cells

2000 • 83 citations

The Central Nervous System Inflammatory Response to Neurotropic Virus Infection Is Peroxynitrite Dependent

2001 • 75 citations

Early myeloid cells are high producers of nitric oxide upon CD40 plus IFN-γ stimulation through a mechanism dependent on endogenous TNF-α and IL-1α

2000 • 50 citations

Decreased L-arginine during peritonitis in ESRD patients on peritoneal dialysis.

1997 • 7 citations