Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity

Nitric oxide and the immune response

2001 • 3,222 citations

Granules of the Human Neutrophilic Polymorphonuclear Leukocyte

1997 • 1,444 citations

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

2002 • 1,141 citations

Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3

2001 • 867 citations

Antigen-Specific Inhibition of CD8+ T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species

2004 • 825 citations

Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of<scp>l</scp>-Arginine Metabolism

2001 • 674 citations

Alternative Metabolic States in Murine Macrophages Reflected by the Nitric Oxide Synthase/Arginase Balance: Competitive Regulation by CD4+ T Cells Correlates with Th1/Th2 Phenotype

1998 • 640 citations

Comparative properties of arginases

1996 • 604 citations

Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells

1999 • 558 citations

Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow‐derived macrophages by TH 1 and TH 2 cytokines

1995 • 553 citations

IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice

2003 • 499 citations

Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis

2003 • 460 citations

<scp>l</scp>-Arginine Consumption by Macrophages Modulates the Expression of CD3ζ Chain in T Lymphocytes

2003 • 458 citations

The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

1981 • 429 citations

Natural Resistance to Intracellular Infections

2000 • 368 citations

Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages.

1990 • 356 citations

Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production

2001 • 310 citations

The Inhibition of Arginase by Nω-Hydroxy-<scp>l</scp>-Arginine Controls the Growth of Leishmania Inside Macrophages

2001 • 262 citations

Phagocytosis by neutrophils induces an amino acid deprivation response in Saccharomyces cerevisiae and Candida albicans

2003 • 220 citations

A Simplified New Assay for Assessment of Fungal Cell Damage with the Tetrazolium Dye, (2,3)-bis-(2-Methoxy-4-Nitro-5-Sulphenyl)-(2H)-Tetrazolium-5-Carboxanilide (XTT)

1995 • 187 citations

Mouse Model for Human Arginase Deficiency

2002 • 165 citations

<scp>l</scp>-Arginine Availability Modulates Local Nitric Oxide Production and Parasite Killing in Experimental Trypanosomiasis

2000 • 164 citations

The human arginases and arginase deficiency

1998 • 162 citations

Arginase I Expression and Activity in Human Mononuclear Cells After Injury

2001 • 160 citations

Arginase 1 Overexpression in Psoriasis

2003 • 159 citations

Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis

2000 • 142 citations

Human Monocytes and Neutrophils Store Transforming Growth Factor-α in a Subpopulation of Cytoplasmic Granules

1997 • 112 citations

The Involvement of Tyrosine Kinases, Cyclic AMP/Protein Kinase A, and p38 Mitogen-Activated Protein Kinase in IL-13-Mediated Arginase I Induction in Macrophages: Its Implications in IL-13-Inhibited Nitric Oxide Production

2000 • 108 citations

Regulation of arginase isoforms I and II by IL-4 in cultured murine peritoneal macrophages

1999 • 93 citations

Arginase and autoimmune inflammation in the central nervous system

2003 • 84 citations

Mechanistic and Metabolic Inferences from the Binding of Substrate Analogues and Products to Arginase^,

2001 • 84 citations

Role of Vesicle-Associated Membrane Protein-2, Through Q-SolubleN-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor/R-SolubleN-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Interaction, in the Exocytosis of Specific and Tertiary Granules of Human Neutrophils

2003 • 79 citations

Differential expression of the two human arginase genes in hyperargininemia. Enzymatic, pathologic, and molecular analysis.

1989 • 60 citations

Divergent effects of GM‐CSF and TGFβ₁on bone marrow‐ derived macrophage arginase‐1 activity, MCP‐1 expression, and matrix‐metalloproteinase‐12: a potential role during arteriogenesis

2003 • 59 citations

Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells

1998 • 41 citations

Co-expression of inducible nitric oxide synthase and arginases in different human monocyte subsets. Apoptosis regulated by endogenous NO

1999 • 39 citations

Induction of arginases I and II in cornea during herpes simplex virus infection

2001 • 34 citations

Patterns of maturation in short-term culture of human acute myeloid leukaemic cells

1979 • 31 citations

Human Phagocytic Cell Responses toScedosporium apiospermum(Pseudallescheria boydii): Variable Susceptibility to Oxidative Injury

2003 • 30 citations

Purification of Arginases from Human‐Leukemic Lymphocytes and Granulocytes: Study of Their Physicochemical and Kinetic Properties

1975 • 29 citations

Immunological Identity of the Two Different Molecular Mass Constltutive Subunits of Liver Arginase

1994 • 13 citations

Delayed neutrophil apoptosis after total body irradiation in mice. The role of granulocyte-macrophage colony-stimulating factor in neutrophil function.

1998 • 4 citations