Innate recognition systems in insect immunity and development: new approaches in

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

1996 • 3,854 citations

Approaching the Asymptote? Evolution and Revolution in Immunology

1989 • 3,079 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Phylogenetic Perspectives in Innate Immunity

1999 • 2,478 citations

The Instructive Role of Innate Immunity in the Acquired Immune Response

1996 • 1,731 citations

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1998 • 1,431 citations

Surface Proteins of Gram-Positive Bacteria and Mechanisms of Their Targeting to the Cell Wall Envelope

1999 • 1,352 citations

BIOLOGICAL MEDIATORS OF INSECT IMMUNITY

1997 • 1,317 citations

Two distinct classes of carbohydrate-recognition domains in animal lectins.

1988 • 1,259 citations

Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells

1989 • 1,251 citations

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

1997 • 1,210 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

Genetic Control of Programmed Cell Death in Drosophila

1994 • 1,028 citations

A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway

1996 • 822 citations

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.

1992 • 818 citations

Mode of action of linear amphipathic α-helical antimicrobial peptides

1998 • 810 citations

Mannose-binding lectin: the pluripotent molecule of the innate immune system

1996 • 727 citations

The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

1998 • 724 citations

Human CD14 mediates recognition and phagocytosis of apoptotic cells

1998 • 685 citations

Apoptosis in resolution of inflammation

1997 • 659 citations

Innate immunity of insects

1995 • 549 citations

Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in Cos-1 cells.

1990 • 501 citations

Purification of a Peptidoglycan Recognition Protein from Hemolymph of the Silkworm, Bombyx mori

1996 • 466 citations

Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.

1996 • 427 citations

Immune reactions in Drosophila and other insects: a model for innate immunity

1993 • 417 citations

Embryonic origin of hemocytes and their relationship to cell death in Drosophila

1994 • 414 citations

The Role of Complement and Its Receptor in the Elimination of Immune Complexes

1986 • 401 citations

CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3).

1998 • 397 citations

Croquemort, A Novel Drosophila Hemocyte/Macrophage Receptor that Recognizes Apoptotic Cells

1996 • 394 citations

CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis.

1995 • 392 citations

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway

1998 • 382 citations

Requirement for Croquemort in Phagocytosis of Apoptotic Cells in Drosophila

1999 • 371 citations

Recognition and phagocytosis of cells undergoing apoptosis

1997 • 330 citations

Scavenger receptors in innate immunity

1996 • 325 citations

Melanogenesis and the Generation of Cytotoxic Molecules During Insect Cellular Immune Reactions

1993 • 322 citations

CD36 Is Required for Phagocytosis of Apoptotic Cells by Human Macrophages That Use Either a Phosphatidylserine Receptor or the Vitronectin Receptor (αvβ3)

1998 • 321 citations

The other side of scavenger receptors: pattern recognition for host defense

1997 • 312 citations

Structure-function relationships of the complement components

1989 • 311 citations

The collectins in innate immunity

1996 • 302 citations

IMMUNITY IN INFECTIVE DISEASES

1906 • 282 citations

Hemolin: an Insect-Immune Protein Belonging to the Immunoglobulin Superfamily

1990 • 247 citations

Expression cloning of dSR-CI, a class C macrophage-specific scavenger receptor from Drosophila melanogaster.

1995 • 243 citations

Immulectin, an inducible C-type lectin from an insect, Manduca sexta, stimulates activation of plasma prophenol oxidase

1999 • 241 citations

Prophenoloxidase Activation: Nonself Recognition and Cell Cooperation in Insect Immunity

1984 • 217 citations

Purification of a beta-1,3-glucan recognition protein in the prophenoloxidase activating system from hemolymph of the silkworm, Bombyx mori.

1988 • 202 citations

Purification of lectin induced in the hemolymph of Sarcophaga peregrina larvae on injury.

1980 • 187 citations

Mannose-Binding Lectin (MBL) in Health and Disease

1998 • 184 citations

Multiple receptors for endotoxin

1991 • 181 citations

Antimicrobial peptide defense in Drosophila

1997 • 180 citations

The lipopolysaccharide‐binding protein participating in hemocyte nodule formation in the silkworm Bombyx mori is a novel member of the C‐type lectin superfamily with two different tandem carbohydrate‐recognition domains¹

1999 • 180 citations

glide/gcmIs Expressed and Required in the Scavenger Cell Lineage

1997 • 170 citations

Distinct and overlapping functions of allelic forms of human mannose binding protein

1992 • 141 citations

Cell surface exposure of phosphatidylserine during apoptosis is phylogenetically conserved

1998 • 131 citations

Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage‐specific monoclonal antibody

1994 • 118 citations

Innate Immunity in Insects: The Role of Multiple, Endogenous Serum Lectins in the Recognition of Foreign Invaders in the Cockroach, Blaberus discoidalis

1999 • 118 citations

Apoptosis of the midline glia during Drosophila embryogenesis: a correlation with axon contact

1995 • 101 citations

C1q Knock-Out Mice for the Study of Complement Deficiency in Autoimmune Disease

1998 • 100 citations

Regulation of the Insect Immune Response: The Effect of Hemolin on Cellular Immune Mechanisms

1996 • 99 citations

Macrophages in Drosophila embryos and L2 cells exhibit scavenger receptor-mediated endocytosis.

1992 • 99 citations

The Eukaryotic Microbial Cell

1981 • 95 citations

Molecular cloning of cDNA for lipopolysaccharide-binding protein from the hemolymph of the American cockroach, Periplaneta americana. Similarity of the protein with animal lectins and its acute phase expression

1991 • 92 citations

Lipopolysaccharide‐Binding Proteins and their Involvement in the Bacterial Clearance from the Hemolymph of the Silkworm Bombyx Mori

1997 • 90 citations

Cell‐Wall Lipopolysaccharides of Ampicillin‐Resistant Mutants of Escherichia coli K‐12

1976 • 89 citations

Helix pomatia Lectin, an Inducer of Drosophila Immune Response, Binds to Hemomucin, a Novel Surface Mucin

1996 • 89 citations

C-Reactive Protein: Structural Biology and Host Defense Function

1999 • 88 citations

Participation of Sarcophagaperegrina humoral lectin in the lysis of sheep red blood cells injected into the abdominal cavity of larvae

1985 • 80 citations

The Bacterial Cell Surface

1984 • 78 citations

The specific recognition by macrophages of CD8+,CD45RO+ T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections.

1994 • 77 citations

The prophenoloxidase cascade in insect immunity

1990 • 77 citations

Cell Adhesion Properties of Hemolin, an Insect Immune Protein in the Ig Superfamily

1997 • 73 citations

Biochemical Studies on Lipopolysaccharides of Salmonella R Mutants

1968 • 73 citations

The Bacterial Cell Surface

1984 • 70 citations

Complement and Complement Deficiencies

1997 • 67 citations

A study of novel lectins and their involvement in the activation of the prophenoloxidase system in Blaberus discoidalis

1995 • 63 citations

Purification, Characterization, and cDNA Cloning of a Galactose-specific C-Type Lectin from Drosophila melanogaster

1996 • 62 citations

Cell Surface Changes Associated with Cellular Immune Reactions in Drosophila

1984 • 55 citations

Studies on the structure of lipopolysaccharides of Salmonella minnesota and Salmonella typhimurium R strains

1965 • 54 citations

Purification and some properties of a lectin from the hemolymph of Periplaneta americana (American cockroach)

1987 • 53 citations

Blood Cell Surface Changes in Drosophila Mutants with Melanotic Tumors

1983 • 52 citations

Detection, isolation and characterization of multiple lectins from the haemolymph of the cockroach Blaberus discoidalis

1993 • 49 citations

Insect Glycobiology: A Lectin Multigene Family in Drosophila melanogaster

1999 • 49 citations

Carbohydrate recognition in the peripheral nervous system: a calcium-dependent membrane binding site for HNK-1 reactive glycolipids potentially involved in Schwann cell adhesion.

1993 • 44 citations

Involvement of Sacrophaga lectin in the development of imaginal discs of Sarcophaga peregrina in an autocrine manner

1991 • 43 citations

Specific immune recognition of insect hemolin

1993 • 40 citations

Nucleosomes inhibit phagocytosis of apoptotic thymocytes by peritoneal macrophages from MRL+/+ lupus-prone mice

1998 • 40 citations

Gliolectin is a novel carbohydrate-binding protein expressed by a subset of glia in the embryonic Drosophila nervous system

1996 • 40 citations

Growth in and breakdown of purified rabbit small intestinal mucin by Yersinia enterocolitica

1993 • 39 citations

Transient Appearance and Localization of a 26-kDa Lectin, a Novel Member of the Periplaneta Lectin Family, in Regenerating Cockroach Leg

1993 • 39 citations

Identification, purification and properties of a β-1,3-glucan-specific lectin from the serum of the cockroach, Blaberus discoidalis which is implicated in immune defence reactions

1999 • 38 citations

A novel role of Periplaneta lectin as an opsonin to recognize 2-Keto-3-deoxy octonate residues of bacterial lipopolysaccharides

1993 • 34 citations

The complement system: pathophysiology and clinical relevance.

1999 • 30 citations

The prophenoloxidase cascade in insect immunity

1990 • 29 citations

A Novel Lectin from Sarcophaga

1998 • 29 citations

Chemokinetic behaviour of insect haemocytes in vitro

1986 • 28 citations

Cloning of cDNA for regenectin, a humoral C-type lectin of Periplaneta americana, and expression of the regenectin gene during leg regeneration

1998 • 21 citations

Localization of regenectin in regenerates of American cockroach (Periplaneta americana) legs.

1991 • 18 citations

Interactions of bacteria with leukocyte integrins

1994 • 11 citations