A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway

Green Fluorescent Protein as a Marker for Gene Expression

1994 • 6,572 citations

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

1996 • 3,854 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

Approaching the Asymptote? Evolution and Revolution in Immunology

1989 • 3,079 citations

NF-κB: Ten Years After

1996 • 3,008 citations

FACS-optimized mutants of the green fluorescent protein (GFP)

1996 • 2,539 citations

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Innate immunity: impact on the adaptive immune response

1997 • 1,542 citations

Human β-Defensin-1 Is a Salt-Sensitive Antibiotic in Lung That Is Inactivated in Cystic Fibrosis

1997 • 1,069 citations

Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid

1996 • 1,042 citations

The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein

1994 • 1,030 citations

Trade-off between parasitoid resistance and larval competitive ability in Drosophila melanogaster

1997 • 727 citations

Widespread expression of beta‐defensin hBD‐1 in human secretory glands and epithelial cells

1996 • 571 citations

Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis

1994 • 482 citations

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides

1994 • 439 citations

NF-κB and Rel Proteins in Innate Immunity

1995 • 435 citations

Epithelial Antibiotics Induced at Sites of Inflammation

1995 • 417 citations

Molecular immune responses of the mosquito Anopheles gambiae to bacteria and malaria parasites

1997 • 373 citations

A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution

1993 • 364 citations

Innate immunity in higher insects

1996 • 358 citations

SIGNALING PATHWAYS THAT ESTABLISH THE DORSAL-VENTRAL PATTERN OF THE DROSOPHILA EMBRYO

1995 • 348 citations

Paneth cell defensins: Endogenous peptide components of intestinal host defense

1996 • 284 citations

Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells.

1996 • 277 citations

The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection.

1990 • 271 citations

Epithelial antibiotic induced in states of disease

1997 • 223 citations

Metchnikowin, a Novel Immune‐Inducible Proline‐Rich Peptide from Drosophila with Antibacterial and Antifungal Properties

1995 • 213 citations

Role of the integument in insect immunity: epicuticular abrasion and induction of cecropin synthesis in cuticular epithelial cells.

1993 • 196 citations

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin

1994 • 183 citations

The andropin gene and its product, a male-specific antibacterial peptide in Drosophila melanogaster.

1991 • 182 citations

Drosophila immunity

1997 • 181 citations

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides.

1990 • 178 citations

Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha

1996 • 160 citations

Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene.

1993 • 155 citations

Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans

1997 • 147 citations

Identification of early genes in the Drosophila immune response by PCR-based differential display: the Attacin A gene and the evolution of attacin-like proteins

1995 • 133 citations

Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen

1990 • 121 citations

CecC, a cecropin gene expressed during metamorphosis in Drosophila pupae

1992 • 107 citations

Signaling Pathways that Establish the Dorsal-Ventral Pattern of the Drosophila Embryo

1995 • 86 citations

Cloning of the Gene Encoding the Antibacterial Peptide Drosocin Involved in Drosophila Immunity

1996 • 52 citations

Molecular Characterization of Ceratotoxin C, a Novel Antibacterial Female‐Specific Peptide of the Ceratotoxin Family from the Medfly Ceratitis Capitata

1996 • 41 citations

EPITHELIAL ANTIBIOTICS INDUCED AT SITES OF INFLAMMATION

1995 • 25 citations

Juvenile hormone regulates the expression of the gene encoding ceratotoxin a, an antibacterial peptide from the female reproductive accessory glands of the medfly Ceratitis capitata

1997 • 23 citations

Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties

1995 • 6 citations

Mise en place de la polarite antero-posterieure de la drosophile au cours de l'ovogenese : etude de la localisation de l'arnm du morphogene bicoid au pole anterieur de l'embryon

1994 • 5 citations