Recognition and phagocytosis of cells undergoing apoptosis

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

1992 • 3,279 citations

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

1995 • 2,877 citations

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

1994 • 2,450 citations

Mechanisms and Functions of Cell Death

1991 • 2,061 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.

1994 • 1,722 citations

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

1989 • 1,540 citations

CD36 is a receptor for oxidized low density lipoprotein

1993 • 1,271 citations

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1994 • 1,071 citations

Phagocyte recognition of cells undergoing apoptosis

1993 • 1,000 citations

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

1990 • 871 citations

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.

1992 • 818 citations

Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes.

1995 • 675 citations

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.

1992 • 605 citations

Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine

1992 • 485 citations

Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus.

1996 • 485 citations

Macrophage recognition of cells undergoing programmed cell death (apoptosis).

1985 • 460 citations

Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor

1993 • 433 citations

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis.

1995 • 422 citations

Croquemort, A Novel Drosophila Hemocyte/Macrophage Receptor that Recognizes Apoptotic Cells

1996 • 394 citations

CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis.

1995 • 392 citations

Neutrophil apoptosis is associated with a reduction in CD16 (Fc gamma RIII) expression.

1994 • 333 citations

Recognition of oxidatively damaged and apoptotic cells by an oxidized low density lipoprotein receptor on mouse peritoneal macrophages: role of membrane phosphatidylserine.

1995 • 293 citations

Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2

1992 • 284 citations

Human monocyte-derived macrophage phagocytosis of senescent eosinophils undergoing apoptosis. Mediation by alpha v beta 3/CD36/thrombospondin recognition mechanism and lack of phlogistic response.

1996 • 244 citations

Apoptotic neutrophils are phagocytosed by fibroblasts with participation of the fibroblast vitronectin receptor and involvement of a mannose/fucose-specific lectin.

1994 • 213 citations

Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis.

1984 • 207 citations

Thrombospondin: a modular adhesive glycoprotein of platelets and nucleated cells.

1987 • 205 citations

Genesis of renal tubular atrophy in experimental hydronephrosis in the rat. Role of apoptosis.

1987 • 193 citations

The clearance of apoptotic cells in the liver is mediated by the asialoglycoprotein receptor

1992 • 185 citations

Granulocyte clearance by apoptosis in the resolution ofinflammation

1995 • 183 citations

Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis.

1995 • 168 citations

Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis

1992 • 163 citations

Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis.

1994 • 161 citations

Recognition of oxidatively damaged erythrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein.

1994 • 151 citations

A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells.

1995 • 144 citations

SRB1, a Class B Scavenger Receptor, Recognizes both Negatively Charged Liposomes and Apoptotic Cells

1996 • 144 citations

Human glomerular mesangial cell phagocytosis of apoptotic neutrophils: mediation by a novel CD36-independent vitronectin receptor/thrombospondin recognition mechanism that is uncoupled from chemokine secretion.

1997 • 131 citations

Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage‐specific monoclonal antibody

1994 • 118 citations

The spontaneous apoptotic cell death of normal human lymphocytes in vitro: The release of, and immunoproliferative response to, nucleosomes in vitro

1991 • 108 citations

Identification of a Domain (155–183) on CD36 Implicated in the Phagocytosis of Apoptotic Neutrophils

1996 • 96 citations

The specific recognition by macrophages of CD8+,CD45RO+ T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections.

1994 • 77 citations