Back to search

Short-chain fatty acid-initiated cell cycle arrest and apoptosis of colonic epithelial cells is linked to mitochondrial function.

Data up to Jan 2025

Published1997
Citations181
References51

Total Citations Per Year

Abstract

References (51)

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1991 • 4,682 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Mitochondrial control of nuclear apoptosis.

1996 • 1,363 citations

Protease activation during apoptosis: Death by a thousand cuts?

1995 • 1,335 citations

Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man.

1980 • 1,265 citations

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

1992 • 949 citations

Classification of human colorectal adenocarcinoma cell lines.

1976 • 943 citations

Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity

1995 • 863 citations

Treatment of Diversion Colitis with Short-Chain-Fatty Acid Irrigation

1989 • 764 citations

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1996 • 746 citations

THE COLONIC EPITHELIUM IN ULCERATIVE COLITIS: AN ENERGY-DEFICIENCY DISEASE?

1980 • 678 citations

Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria

1994 • 577 citations

Programmed cell death and Bcl-2 protection in the absence of a nucleus.

1994 • 560 citations

Inhibition of apoptosis during development of colorectal cancer.

1995 • 548 citations

Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53‐independent pathway: Implications for the possible role of dietary fibre in the prevention of large‐bowel cancer

1993 • 539 citations

Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.

1995 • 433 citations

Mitochondrial respiratory chain inhibitors induce apoptosis

1994 • 403 citations

Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.

1993 • 390 citations

Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines.

1994 • 365 citations

Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells.

1982 • 356 citations

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

1994 • 320 citations

Proctitis and colitis following diversion of the fecal stream

1981 • 315 citations

N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells.

1979 • 261 citations

Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells.

1993 • 256 citations

Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells

1980 • 237 citations

A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells.

1996 • 229 citations

Loss of Function of Cytochrome c in Jurkat Cells Undergoing Fas-mediated Apoptosis

1996 • 225 citations

Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondria.

1987 • 206 citations

Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.

1996 • 202 citations

Evolution of a Regulatory Enzyme: Cytochrome-c Oxidase (Complex IV)

1987 • 193 citations

Organic anions and the diarrhea of inflammatory bowel disease

1988 • 190 citations

A comparison of cell replacement in bone marrow, testis and three regions of surface epithelium

1979 • 180 citations

Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity.

1993 • 163 citations

The anti-proliferative effect of sulindac and sulindac sulfide on HT-29 colon cancer cells: alterations in tumor suppressor and cell cycle-regulatory proteins.

1996 • 151 citations

Metabolic induction of experimental ulcerative colitis by inhibition of fatty acid oxidation.

1986 • 140 citations

Effects of differentiation‐inducing agents on maturation of human MCF‐7 breast cancer cells

1990 • 101 citations

Chapter 5 Cell Cycle Analysis of Apoptosis Using Flow Cytometry

1995 • 88 citations

Expression of mitochondrial cytochrome c oxidase in human colonic cell differentiation, transformation, and risk for colonic cancer.

1990 • 82 citations

Apoptosis and the cell cycle.

1994 • 76 citations

METABOLIC BASIS OF STARVATION DIARRHOEA: IMPLICATIONS FOR TREATMENT

1986 • 67 citations

Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells

1993 • 63 citations

Patterns of gene expression that characterize the colonic mucosa in patients at genetic risk for colonic cancer.

1991 • 62 citations

A study of some mitochondrial and peroxisomal enzymes in human colonic adenocarcinoma.

1981 • 48 citations

Bacterial short-chain fatty acids and mucosal diseases of the colon

1988 • 44 citations

Control of HL-60 monocytic differentiation

1987 • 39 citations

Expression of the Mammalian Mitochondrial Genome

1989 • 28 citations

Expression of the mammalian mitochondrial genome. Role for membrane potential in the production of mature translation products.

1990 • 27 citations

Steady-state levels of mitochondrial messenger RNA species characterize a predominant pathway culminating in apoptosis and shedding of HT29 human colonic carcinoma cells.

1996 • 26 citations

Recent Advances in the Study of Mitochondria in Living Cells

1988 • 23 citations

The effects of sodium butyrate on lymphokine production.

1985 • 5 citations

Cited By (0)

Loading...
Short-chain fatty acid-initiated cell cycle arrest and apoptosis of colonic epithelial… (1997) – PubMed | Metascience Observatory Explorer