Vaccination of Macaques with Long-Standing SIVmac251 Infection Lowers the Viral Set Point After Cessation of Antiretroviral Therapy

Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

1998 • 9,382 citations

Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy

1997 • 2,989 citations

Control of Viremia in Simian Immunodeficiency Virus Infection by CD8 ⁺ Lymphocytes

1999 • 2,206 citations

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia

1997 • 2,154 citations

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

1997 • 1,911 citations

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

1998 • 1,890 citations

Vigorous HIV-1-Specific CD4 ⁺ T Cell Responses Associated with Control of Viremia

1997 • 1,868 citations

HIV preferentially infects HIV-specific CD4+ T cells

2002 • 1,246 citations

lnterleukin-2 programs mouse αβ T lymphocytes for apoptosis

1991 • 1,027 citations

Immune control of HIV-1 after early treatment of acute infection

2000 • 1,012 citations

HIV-Specific Cd8+ T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function

2000 • 879 citations

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

1999 • 766 citations

Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4 ⁺ and CD8 ⁺ T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection

2001 • 693 citations

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

2000 • 693 citations

Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral Therapy

1999 • 619 citations

Prevention of SIV Infection in Macaques by ( R )-9-(2-Phosphonylmethoxypropyl)adenine

1995 • 560 citations

Administration of an Anti-CD8 Monoclonal Antibody Interferes with the Clearance of Chimeric Simian/Human Immunodeficiency Virus during Primary Infections of Rhesus Macaques

1998 • 502 citations

Use of overlapping peptide mixtures as antigens for cytokine flow cytometry

2001 • 358 citations

Decay Kinetics of Human Immunodeficiency Virus-Specific Effector Cytotoxic T Lymphocytes after Combination Antiretroviral Therapy

1999 • 350 citations

Analysis of Gag-specific Cytotoxic T Lymphocytes in Simian Immunodeficiency Virus–infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I–Peptide Complex

1998 • 281 citations

Impaired function of circulating HIV-specific CD8+ T cells in chronic human immunodeficiency virus infection

2000 • 273 citations

HIV-1–specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy

1999 • 240 citations

ALVAC-SIV-gag-pol-env-Based Vaccination and Macaque Major Histocompatibility Complex Class I (A*01) Delay Simian Immunodeficiency Virus SIV_mac-Induced Immunodeficiency

2002 • 235 citations

Identification of Dynamically Distinct Subpopulations of T Lymphocytes That Are Differentially Affected by HIV

2001 • 227 citations

Characterization of the Peptide Binding Motif of a Rhesus MHC Class I Molecule (Mamu-A*01) That Binds an Immunodominant CTL Epitope from Simian Immunodeficiency Virus

1998 • 220 citations

A Significant Number of Human Immunodeficiency Virus Epitope-Specific Cytotoxic T Lymphocytes Detected by Tetramer Binding Do Not Produce Gamma Interferon

2000 • 201 citations

Control of SIV Rebound Through Structured Treatment Interruptions During Early Infection

2000 • 192 citations

Viremia control following antiretroviral treatment and therapeutic immunization during primary SIV251 infection of macaques

2000 • 190 citations

The Effect of Commencing Combination Antiretroviral Therapy Soon after Human Immunodeficiency Virus Type 1 Infection on Viral Replication and Antiviral Immune Responses

1999 • 181 citations

Immunologic and Virologic Effects of Subcutaneous Interleukin 2 in Combination With Antiretroviral Therapy

2000 • 179 citations

Rational interleukin 2 therapy for HIV positive individuals: daily low doses enhance immune function without toxicity.

1996 • 168 citations

Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects

2001 • 164 citations

Decay Kinetics of Human Immunodeficiency Virus-Specific CD8⁺T Cells in Peripheral Blood after Initiation of Highly Active Antiretroviral Therapy

2001 • 160 citations

Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4+ and CD8+ T Cell Responses

2002 • 159 citations

CD8⁺Lymphocytes from Simian Immunodeficiency Virus-Infected Rhesus Macaques Recognize 14 Different Epitopes Bound by the Major Histocompatibility Complex Class I Molecule Mamu-A*01: Implications for Vaccine Design and Testing

2001 • 151 citations

Containment of Simian Immunodeficiency Virus Infection: Cellular Immune Responses and Protection from Rechallenge following Transient Postinoculation Antiretroviral Treatment

2000 • 149 citations

Recombinant Vaccine-Induced Protection against the Highly Pathogenic Simian Immunodeficiency Virus SIV_mac251: Dependence on Route of Challenge Exposure

1998 • 146 citations

Discontinuation of Antiretroviral Therapy Commenced Early during the Course of Human Immunodeficiency Virus Type 1 Infection, with or without Adjunctive Vaccination

2002 • 139 citations

Enhancement of Human Immunodeficiency Virus Type 1–Specific CD4 and CD8 T Cell Responses in Chronically Infected Persons after Temporary Treatment Interruption

2000 • 118 citations

Structured Treatment Interruptions for the Management of HIV Infection

2001 • 108 citations

Impaired function of circulating HIV-specific CD8+ T cells in chronic human immunodeficiency virus infection

2000 • 103 citations

Potentiation of Simian Immunodeficiency Virus (SIV)-Specific CD4+ and CD8+ T Cell Responses by a DNA-SIV and NYVAC-SIV Prime/Boost Regimen

2001 • 93 citations

Functional Impairment of Simian Immunodeficiency Virus-Specific CD8⁺T Cells during the Chronic Phase of Infection

2001 • 88 citations

Safety and Immunogenicity of ALVAC vCP1452 and Recombinant gp160 in Newly Human Immunodeficiency Virus Type 1-Infected Patients Treated with Prolonged Highly Active Antiretroviral Therapy

2002 • 85 citations

Nasba Technology: Isothermal RNA Amplification in Qualitative and Quantitative Diagnostics

1997 • 84 citations

Suppression of Acute Viremia by Short-Term Postexposure Prophylaxis of Simian/Human Immunodeficiency Virus SHIV-RT-Infected Monkeys with a Novel Reverse Transcriptase Inhibitor (GW420867) Allows for Development of Potent Antiviral Immune Responses Resulting in Efficient Containment of Infection

2000 • 72 citations

Impairment of Gag-Specific CD8⁺T-Cell Function in Mucosal and Systemic Compartments of Simian Immunodeficiency Virus mac251- and Simian-Human Immunodeficiency Virus KU2-Infected Macaques

2001 • 67 citations

Adoptive transfer of simian immunodeficiency virus (SIV) naı̈ve autologous CD4+ cells to macaques chronically infected with SIV is sufficient to induce long-term nonprogressor status

2002 • 59 citations

A novel chimeric Rev, Tat, and Nef (Retanef) antigen as a component of an SIV/HIV vaccine

2002 • 47 citations

Equivalent Immunogenicity of the Highly Attenuated Poxvirus-Based ALVAC-SIV and NYVAC-SIV Vaccine Candidates in SIVmac251-Infected Macaques

2002 • 47 citations

To cure chronic HIV infection, a new therapeutic strategy is needed

2001 • 23 citations

Emergence of Cytotoxic T Lymphocyte Escape Mutants following Antiretroviral Treatment Suspension in Rhesus Macaques Infected with SIVmac251

2002 • 22 citations

Modeling immune intervention strategies for HIV-1 infection of humans in the macaque model

2002 • 8 citations

In Vivo Assessment of Antiviral Reactivity in Chronic HIV Infection

2000 • 8 citations