Suppression of Acute Viremia by Short-Term Postexposure Prophylaxis of Simian/Human Immunodeficiency Virus SHIV-RT-Infected Monkeys with a Novel Reverse Transcriptase Inhibitor (GW420867) Allows for Development of Potent Antiviral Immune Responses Resulting in Efficient Containment of Infection

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less

1997 • 2,670 citations

Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia

1997 • 2,154 citations

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1999 • 2,083 citations

Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy

1997 • 1,912 citations

Vigorous HIV-1-Specific CD4 ⁺ T Cell Responses Associated with Control of Viremia

1997 • 1,868 citations

Positive Effects of Combined Antiretroviral Therapy on CD4 ⁺ T Cell Homeostasis and Function in Advanced HIV Disease

1997 • 1,812 citations

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1991 • 1,613 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

Quantifying Residual HIV-1 Replication in Patients Receiving Combination Antiretroviral Therapy

1999 • 824 citations

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

1995 • 650 citations

Prevention of SIV Infection in Macaques by ( R )-9-(2-Phosphonylmethoxypropyl)adenine

1995 • 560 citations

Measuring Recent Thymic Emigrants in Blood of Normal and HIV-1–Infected Individuals before and after Effective Therapy

1999 • 354 citations

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus

1996 • 325 citations

Identification of Highly Attenuated Mutants of Simian Immunodeficiency Virus

1998 • 226 citations

Plasma viremia in macaques infected with simian immunodeficiency virus: plasma viral load early in infection predicts survival

1997 • 224 citations

Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys

1993 • 218 citations

A Pathogenic Threshold of Virus Load Defined in Simian Immunodeficiency Virus- or Simian-Human Immunodeficiency Virus-Infected Macaques

1998 • 166 citations

Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry

1993 • 143 citations

Spontaneous and antigen-induced production of HIV-inhibitory β-chemokines are associated with AIDS-free status

1999 • 142 citations

Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus

1997 • 142 citations

Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors.

1995 • 131 citations

Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication

1995 • 85 citations

In VitroImmortalization of Old World Monkey T Lymphocytes withHerpesvirus Saimiri:Its Susceptibility to Infection with Simian Immunodeficiency Viruses

1996 • 78 citations

CD8 ⁺ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression

2000 • 74 citations

Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and β-chemokine production

1999 • 74 citations

Helper T cell determinant peptide contributes to induction of cellular immune responses by peptide vaccines against hepatitis C virus.

1999 • 40 citations

Resistance mutations selected in vivo under therapy with anti-HIV drug HBY 097 differ from resistance pattern selected in vitro

1999 • 15 citations

Can Immune Systems Be Trained to Fight HIV?

1999 • 10 citations