Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

1996 • 3,496 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy

1997 • 2,989 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia

1997 • 2,154 citations

Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

1997 • 2,011 citations

Decay characteristics of HIV-1-infected compartments during combination therapy

1997 • 1,849 citations

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1993 • 1,822 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1993 • 1,450 citations

Cytokine-Induced Expression of HIV-1 in a Chronically Infected Promonocyte Cell Line

1987 • 936 citations

Multifactorial Nature of Human Immunodeficiency Virus Disease: Implications for Therapy

1993 • 803 citations

In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency

1995 • 755 citations

The Reservoir for HIV-1 in Human Peripheral Blood Is a T Cell That Maintains Expression of CD4

1989 • 732 citations

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

1989 • 726 citations

Lifespan of human lymphocyte subsets defined by CD45 isoforms

1992 • 642 citations

Kinetics of Response in Lymphoid Tissues to Antiretroviral Therapy of HIV-1 Infection

1997 • 631 citations

Virus dynamics and drug therapy

1997 • 618 citations

Quiescent T Lymphocytes as an Inducible Virus Reservoir in HIV-1 Infection

1991 • 584 citations

Repetitive Sequences in Eukaryotic DNA and their Expression

1982 • 575 citations

Lymphoid organs function as major reservoirs for human immunodeficiency virus.

1991 • 489 citations

Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.

1990 • 443 citations

Controlling HIV pathogenesis: the role of the noncytotoxic anti-HIV response of CD8+ T cells

1996 • 434 citations

Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle

1992 • 399 citations

Effect of Immunization with a Common Recall Antigen on Viral Expression in Patients Infected with Human Immunodeficiency Virus Type 1

1996 • 379 citations

HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay

1992 • 353 citations

Activation of virus replication after vaccination of HIV-1-infected individuals.

1995 • 332 citations

New Concepts in the Immunopathogenesis of HIV Infection

1995 • 323 citations

Induction of HTLV-III/LAV from a Nonvirus-Producing T-Cell Line: Implications for Latency

1986 • 264 citations

Anti-viral Drug Treatment: Dynamics of Resistance in Free Virus and Infected Cell Populations

1997 • 251 citations

Human immunodeficiency virus type 1 replication is blocked prior to reverse transcription and integration in freshly isolated peripheral blood monocytes

1996 • 221 citations

Changing the natural history of HIV disease

1996 • 136 citations

Dilution assay statistics

1994 • 136 citations

Blocked early-stage latency in the peripheral blood cells of certain individuals infected with human immunodeficiency virus type 1.

1992 • 102 citations

Migration pathways and immunologic memory among T lymphocytes.

1992 • 97 citations

High viral load in lymph nodes and latent human immunodeficiency virus (HIV) in peripheral blood cells of HIV-1-infected chimpanzees

1993 • 81 citations

Nuclear import of HIV-1 DNA in resting CD4+ T cells requires a cyclosporin A-sensitive pathway.

1997 • 55 citations

Human immunodeficiency virus type 1 may preferentially integrate into chromatin occupied by L1Hs repetitive elements.

1994 • 51 citations

Rapid Decrease in Unintegrated Human Immunodeficiency Virus DNA after the Initiation of Nucleoside Therapy

1994 • 13 citations