Mechanisms of transcriptional activation: differences and similarities between yeast, Drosophila, and man

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 1,001 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 653 citations

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1993 • 589 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

p53 Transcriptional Activation Mediated by Coactivators TAF _II 40 and TAF _II 60

1995 • 438 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

DNA topoisomerase I is involved in both repression and activation of transcription

1993 • 380 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

1994 • 361 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 334 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 299 citations

Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences.

1989 • 291 citations

TBP-associated factors are not generally required for transcriptional activation in yeast

1996 • 289 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

General requirement for RNA polymerase II holoenzymes in vivo.

1995 • 249 citations

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

1995 • 247 citations

Transcription activation in cells lacking TAFIIs

1996 • 238 citations

Association of an activator with an RNA polymerase II holoenzyme.

1995 • 237 citations

A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators

1994 • 203 citations

Promoter-Selective Transcriptional Defect in Cell Cycle Mutant ts13 Rescued by hTAF _II 250

1994 • 163 citations

Yeast TAF IIS in a multisubunit complex required for activated transcription

1994 • 163 citations

A mammalian SRB protein associated with an RNA polymerase II holoenzyme

1996 • 144 citations

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.

1996 • 141 citations

Gene activation by recruitment of the RNA polymerase II holoenzyme.

1996 • 123 citations

Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4.

1996 • 116 citations

The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation.

1995 • 113 citations

The human general co-factors

1996 • 105 citations

Mediator of transcriptional regulation

1996 • 103 citations

Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences

1989 • 100 citations

DNA Template and Activator-Coactivator Requirements for Transcriptional Synergism by Drosophila Bicoid

1995 • 89 citations

Immunopurification of yeast TATA-binding protein and associated factors. Presence of transcription factor IIIB transcriptional activity

1993 • 88 citations

The human general co-factors

1996 • 74 citations

Functional differences between mammalian transcription activation domains at the yeast GAL1 promoter.

1994 • 72 citations

Mediator of transcriptional regulation

1996 • 67 citations

RETRACTED: TAFIIs Mediate Activation of Transcription in the Drosophila Embryo

1996 • 64 citations

TAFIIs Mediate Activation of Transcription in theDrosophilaEmbryo

1998 • 61 citations

Genome sequencing: The complete code for a eukaryotic cell

1996 • 55 citations

The Glutamine-Rich Activation Domains of Human Sp1 Do Not Stimulate Transcription in Saccharomyces cerevisiae

1995 • 55 citations