Induction of Antigen-Specific Cytotoxic T Lymphocytes in Humans by a Malaria DNA Vaccine

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

1993 • 1,122 citations

DNA VACCINES

1997 • 977 citations

Molecular analysis of the association of HLA-B53 and resistance to severe malaria

1992 • 645 citations

First Human Trial of a DNA-Based Vaccine for Treatment of Human Immunodeficiency Virus Type 1 Infection: Safety and Host Response

1998 • 637 citations

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

1994 • 453 citations

Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients

1998 • 409 citations

Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination

1997 • 364 citations

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity.

1996 • 257 citations

DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines.

1996 • 221 citations

Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes.

1990 • 210 citations

Degenerate Cytotoxic T Cell Epitopes from P. falciparum Restricted by Multiple HLA-A and HLA-B Supertype Alleles

1997 • 186 citations

Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein.

1991 • 147 citations

Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria

1995 • 147 citations

Simian immunodeficiency virus-specific cytotoxic T-lymphocyte induction through DNA vaccination of rhesus monkeys

1996 • 138 citations

NYVAC-Pf7: a poxvirus-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria

1996 • 125 citations

An OspA-Based DNA Vaccine Protects Mice against Infection with Borrelia burgdorferi

1997 • 107 citations

Localization of HLA-A2.1-restricted T cell epitopes in the circumsporozoite protein of Plasmodium falciparum.

1995 • 69 citations

Naturally acquired CD8+ cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein.

1992 • 68 citations

Simultaneous Induction of Multiple Antigen-Specific Cytotoxic T Lymphocytes in Nonhuman Primates by Immunization with a Mixture of Four Plasmodium falciparum DNA Plasmids

1998 • 67 citations

Geographically restricted heterogeneity of the Plasmodium falciparum circumsporozoite protein: relevance for vaccine development

1992 • 56 citations

Location of human cytotoxic T cell epitopes within a polymorphic domain of the Plasmodium falciparum circumsporozoite protein

1991 • 55 citations

Induction of immunodeficiency virus‐specific immune responses in rhesus monkeys following gene gun‐mediated DNA vaccination

1996 • 55 citations

In vitro expression and in vivo immunogenicity of Plasmodium falciparum pre-erythrocytic stage DNA vaccines.

1998 • 33 citations

Toward clinical trials of DNA vaccines against malaria

1997 • 32 citations

DNA sequence of the gene encoding aPlasmodium falciparummalaria candidate vaccine antigen

1989 • 18 citations

Class I HLA-restricted cytotoxic T lymphocyte responses against malaria-elucidation on the basis of HLA peptide binding motifs

1996 • 17 citations

Antigenic diversity and MHC genetics in sporozoite immunity

1994 • 6 citations