Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Genetic immunization is a simple method for eliciting an immune response

1992 • 1,505 citations

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

1993 • 1,122 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

Gene inoculation generates immune responses against human immunodeficiency virus type 1.

1993 • 655 citations

CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites.

1988 • 477 citations

Gene Therapy by Intramuscular Injection of Plasmid DNA: Studies on Firefly Luciferase Gene Expression in Mice

1993 • 440 citations

Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA

1993 • 432 citations

Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA

1993 • 344 citations

Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria.

1993 • 265 citations

CD8⁺ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria

1991 • 215 citations

Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes.

1990 • 210 citations

Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein

1991 • 188 citations

Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum

1988 • 180 citations

Sporozoite Vaccine Induces Genetically Restricted T Cell Elimination of Malaria from Hepatocytes

1989 • 177 citations

Monoclonal, but not polyclonal, antibodies protect against Plasmodium yoelii sporozoites.

1991 • 127 citations

Plasmid DNAs directly injected into mouse brain with lipofectin can be incorporated and expressed by brain cells

1990 • 124 citations

Effector functions of circumsporozoite peptide-primed CD4+ T cell clones against Plasmodium yoelii liver stages.

1993 • 113 citations

A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei.

1992 • 109 citations

Structure of the gene encoding the circumsporozoite protein of Plasmodium yoelii. A rodent model for examining antimalarial sporozoite vaccines.

1987 • 85 citations

Characterization of the gene encoding sporozoite surface protein 2, a protective Plasmodium yoelii sporozoite antigen

1992 • 67 citations

Rapid, large-scale isolation of Plasmodium berghei sporozoites from infected mosquitoes.

1979 • 67 citations

Technological Advances in Vaccine Development

1987 • 56 citations

Evaluation of an in vitro assay aimed at measuring protective antibodies against sporozoites.

1990 • 45 citations

A malaria sporozoite surface antigen distinct from the circumsporozoite protein.

1990 • 41 citations

Recombinant pseudorabies virus carrying a plasmodium gene: herpesvirus as a new live viral vector for inducing T- and B-cell immunity☆

1992 • 38 citations

In vivo testing of subunit vaccines against malaria sporozoites using a rodent system.

1987 • 22 citations

Cloning of Plasmodium yoelii genes expressing three different sporozoite-specific antigens

1989 • 9 citations

A Rapid Method for Screening Antibodies to Plasmodium yoelii Liver Stages by Immunofluorescence

1987 • 2 citations