Aging in Rhesus Monkeys: Relevance to Human Health Interventions

The retardation of aging and disease by dietary restriction

1989 • 1,494 citations

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

2001 • 1,050 citations

Biomarkers of Caloric Restriction May Predict Longevity in Humans

2002 • 443 citations

Altered cytokine production in the elderly

1998 • 379 citations

Cyclic Estrogen Replacement Improves Cognitive Function in Aged Ovariectomized Rhesus Monkeys

2003 • 348 citations

Age-related Dendritic and Spine Changes in Corticocortically Projecting Neurons in Macaque Monkeys

2003 • 306 citations

Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents.

1996 • 305 citations

Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging

2004 • 285 citations

Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys

2002 • 284 citations

Calorie restriction in rhesus monkeys

2003 • 256 citations

Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy

1999 • 241 citations

Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence.

1996 • 237 citations

Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study

2000 • 201 citations

Characterization of the Onset of Menopause in the Rhesus Macaque1

1997 • 176 citations

Dehydroepiandrosterone Sulfate: A Biomarker of Primate Aging Slowed by Calorie Restriction

1997 • 167 citations

Methods in Aging Research

1998 • 149 citations

Nonhuman Primate Models of Menopause Workshop1

2003 • 148 citations

Preservation of hippocampal neuron numbers in aged rhesus monkeys

2002 • 134 citations

Age- and gender-related changes in body size, adiposity, and endocrine and metabolic parameters in free-ranging rhesus macaques

1992 • 125 citations

Long-Term Dietary Restriction in Older-Aged Rhesus Monkeys: Effects on Insulin Resistance

1995 • 123 citations

In vivo gene delivery of glial cell line-derived neurotrophic factor for Parkinson's disease

2003 • 120 citations

Chapter 36 Structural changes in the normally aging cerebral cortex of primates

2002 • 113 citations

Neuroendocrine Modulation and Repercussions of Female Reproductive Aging

2002 • 106 citations

Aged Non‐Human Primates: An Animal Model of Age‐Associated Neurodegenerative Disease

1991 • 97 citations

Impairments in acquisition and reversals of two-choice discriminations by aged rhesus monkeys

1999 • 93 citations

Radiation-Induced Endometriosis in Macaca mulatta

1991 • 83 citations

The metabolic syndrome: an emerging health epidemic in women

2004 • 82 citations

Motor Slowing and Parkinsonian Signs in Aging Rhesus Monkeys Mirror Human Aging

2000 • 79 citations

Cerebral amyloid angiopathy and plaques, and visceral amyloidosis in aged macaques

1996 • 70 citations

Distribution, progression and chemical composition of cortical amyloid-β deposits in aged rhesus monkeys: similarities to the human

2003 • 69 citations

Slowing ageing by caloric restriction

1995 • 65 citations

Loss of D₂ Receptor Binding with Age in Rhesus Monkeys: Importance of Correction for Differences in Striatal Size

1999 • 61 citations

Dietary Caloric Restriction Prevents the Age-Related Decline in Plasma Melatonin Levels of Rhesus Monkeys

2001 • 60 citations

Age-related decline in striatal volume in monkeys as measured by magnetic resonance imaging

2000 • 58 citations

Age-related changes in auditory function of rhesus monkeys (Macaca mulatta)

2000 • 56 citations

A nonhuman primate model of age-related bone loss: a longitudinal study in male and premenopausal female rhesus monkeys

2001 • 52 citations

Reduction in hippocampal cholinergic innervation is unrelated to recognition memory impairment in aged rhesus monkeys

2004 • 50 citations

Brain Weight Does Not Decrease with Age in Adult Rhesus Monkeys

1998 • 48 citations

The occurrence of senile cataracts, ocular hypertension and glaucoma in rhesus monkeys

1982 • 44 citations

Spontaneous intestinal adenocarcinoma in geriatric macaques (Macaca sp.).

2000 • 39 citations

Effect of Age and Caloric Restriction on Cutaneous Wound Closure in Rats and Monkeys

1997 • 39 citations

Locomotor Activity in Female Rhesus Monkeys: Assessment of Age and Calorie Restriction Effects

2000 • 39 citations

Age-related changes in cytokine production by leukocytes in rhesus monkeys

2001 • 36 citations

The Effects of K-111, a New Insulin-sensitizer, on Metabolic Syndrome in Obese Prediabetic Rhesus Monkeys

2003 • 34 citations

Spinal degenerative disk disease (DDD) in female macaque monkeys: epidemiology and comparison with women

2002 • 32 citations

Cholinergic activity of aged rhesus monkeys revealed by positron emission tomography

2000 • 29 citations

Induction of human breast cancer-specific antibody responses in cynomolgus monkeys by a murine monoclonal anti-idiotype antibody.

1995 • 26 citations

The Androgen Status of Aging Male Rhesus Macaques*

1986 • 23 citations

Pathological changes in the reproductive tract of male Rhesus monkeys associated with age and simian AIDS

1992 • 21 citations

Changes in blood chemistry and hematology variables during aging in captive rhesus macaques (Macaca mulatta). J Med Primatol 30:161–173, 2001

2004 • 20 citations

Prostatic Carcinoma in a Rhesus Monkey (Macaca mulatta)

1985 • 18 citations

Cell Culture Systems as Tools for Studying Age-Related Changes in Skeletal Muscle

1995 • 16 citations

REVIEW The use of nonhuman primate models to improve gene transfer into haematopoietic stem cells

2001 • 15 citations

Rhesus macaque model for ovarian cancer chemoprevention.

2001 • 13 citations

Reverse transcription of inserted DNA in a monkey gives us ANDi

2001 • 1 citations