Calorie restriction in rhesus monkeys

The aging process.

1981 • 1,871 citations

The retardation of aging and disease by dietary restriction

1989 • 1,494 citations

Age Changes and Sex Differences in Serum Dehydroepiandrosterone Sulfate Concentrations throughout Adulthood

1984 • 1,345 citations

Handbook of the Biology of Aging

1990 • 1,219 citations

A Prospective Study of Dehydroepiandrosterone Sulfate, Mortality, and Cardiovascular Disease

1986 • 683 citations

Biomarkers of Caloric Restriction May Predict Longevity in Humans

2002 • 443 citations

Decreased Food Intake With Aging

2001 • 419 citations

Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men.

1992 • 391 citations

Does Malnutrition Affect Fecundity? A Summary of Evidence

1980 • 338 citations

Hip Fracture Prediction in Elderly Men and Women: Validation in the Rotterdam Study

1998 • 330 citations

Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents.

1996 • 305 citations

Dietary Restriction Alters Characteristics of Glucose Fuel Use

1992 • 304 citations

The pineal gland and melatonin in relation to aging: A summary of the theories and of the data

1995 • 287 citations

Effect of chronic caloric restriction on physiological variables related to energy metabolism in the male Fischer 344 rat

1989 • 251 citations

Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys

1994 • 235 citations

Decreased HDL2 and HDL3 cholesterol, Apo A-I and Apo A-II, and increased risk of myocardial infarction.

1992 • 229 citations

Abdominal obesity is associated with accelerated progression of carotid atherosclerosis in men

2001 • 227 citations

Dietary Restriction and Aging: The Initiation of a Primate Study

1990 • 220 citations

Body Size and Hip Fracture Risk in Older Women

1997 • 213 citations

Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men

1992 • 207 citations

Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study

2000 • 201 citations

Effect of Age and Diet on Insulin Secretion and Insulin Action in the Rat

1983 • 168 citations

Dehydroepiandrosterone Sulfate: A Biomarker of Primate Aging Slowed by Calorie Restriction

1997 • 167 citations

Testosterone and the aging male.

1997 • 162 citations

Hibernation and Longevity in the Turkish Hamster Mesocricetus brandti

1981 • 154 citations

Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk

1999 • 146 citations

Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points

1995 • 140 citations

Modulation of aging processes by dietary restriction

1994 • 140 citations

Serum dehydroepiandrosterone sulfate levels as an individual marker.

1994 • 136 citations

Testosterone and the Aging Male

1997 • 130 citations

Age- and gender-related changes in body size, adiposity, and endocrine and metabolic parameters in free-ranging rhesus macaques

1992 • 125 citations

Abnormal 24-hr mean plasma concentrations of dehydroisoandrosterone and dehydroisoandrosterone sulfate in women with primary operable breast cancer.

1981 • 121 citations

Activity Measures in Rhesus Monkeys on Long-Term Calorie Restriction

1997 • 120 citations

Acute effects of melatonin administration on cardiovascular autonomic regulation in healthy men

2001 • 108 citations

Modulation of aging processes by dietary restriction

1995 • 102 citations

Dehydroepiandrosterone sulphate and dehydroepiandrosterone in serum: differences related to age and sex

1988 • 95 citations

Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk

1999 • 93 citations

Effects of intermittent feeding upon growth, activity, and lifespan in rats allowed voluntary exercise

1983 • 92 citations

Short-term calorie restriction improves disease-related markers in older male rhesus monkeys (Macaca mulatta)

2000 • 90 citations

A Radiographic standard of reference for the growing hand and wrist

1971 • 86 citations

Serum profiles of LH, FSH, testosterone and 5α-DHT from 21 to 1000 days of age in AD Libitum fed and dietary restricted rats

1981 • 83 citations

Beyond the rodent model: Calorie restriction in rhesus monkeys

1997 • 82 citations

Aging and Dietary Modulation of Rat Skeleton and Parathyroid Hormone*

1984 • 81 citations

Effect of Chronic Caloric Restriction on the Circadian Regulation of Physiological and Behavioral Variables in Old Male B₆C₃F₁Mice

1990 • 81 citations

Therapeutic controversy: Estrogen replacement in menopause.

1996 • 79 citations

Food restriction retards aging of the pineal gland

1991 • 79 citations

Program for testing biological interventions to promote healthy aging

2000 • 79 citations

Serum dehydroepiandrosterone sulfate levels as an individual marker

1994 • 74 citations

Temporal and Compositional Dietary Restrictions Modulate Age-Related Changes in Serum Lipids

1983 • 73 citations

Adrenocortical Responsiveness to Graded ACTH Infusions in Normal Young and Elderly Human Subjects

1986 • 70 citations

Dietary Restriction in Nonhuman Primates: Progress Report on the NIA Study

1992 • 66 citations

Caloric restriction increases HDL₂levels in rhesus monkeys (Macaca mulatta)

1997 • 66 citations

Lifelong food restriction prevents senile osteopenia and hyperparathyroidism in F344 rats

1984 • 65 citations

Aging and food restriction alter some indices of bone metabolism in male rhesus monkeys (Macaca mulatta).

1995 • 63 citations

Use of Melatonin in the Treatment of Phase Shift and Sleep Disorders

1999 • 61 citations

Factors associated with serum alkaline phosphatase level.

1993 • 61 citations

Dietary Caloric Restriction Prevents the Age-Related Decline in Plasma Melatonin Levels of Rhesus Monkeys

2001 • 60 citations

Serum dehydroepiandrosterone sulfate concentrations across the life span of laboratory‐housed rhesus monkeys

2000 • 59 citations

Energy Restriction Does Not Alter Bone Mineral Metabolism or Reproductive Cycling and Hormones in Female Rhesus Monkeys

2001 • 59 citations

Melatonin: Therapeutic Use in Sleep Disorders

1997 • 57 citations

Effect of age and diet on insulin secretion and insulin action in the rat

1983 • 56 citations

Influence of Fat Intake and Caloric Restriction on Bone in Aging Male Rats

1997 • 55 citations

Modification of the oestrous cycle hormonal profile by dietary restriction

1985 • 51 citations

Energy Balance in Rhesus Monkeys (Macaca mulatta) Subjected to Long-term Dietary Restriction

1995 • 47 citations

Evaluating measures of hematology and blood chemistry in male rhesus monkeys as biomarkers of aging

1994 • 47 citations

Melatonin: marvel or marker?

1998 • 47 citations

Nonhuman Primate Models of Skeletal and Reproductive Aging

2002 • 47 citations

Calorie Restriction in Nonhuman Primates: Implications for Age-Related Disease Risk

1998 • 44 citations

Calorie Restriction and Skeletal Mass in Rhesus Monkeys (Macaca mulatta): Evidence for an Effect Mediated Through Changes in Body Size

2001 • 44 citations

Measures of body size and growth in rhesus and squirrel monkeys subjected to long‐term dietary restriction

1995 • 42 citations

Pineal peptide preparation epithalamin increases the lifespan of fruit flies, mice and rats

1998 • 40 citations

Plasma Concentrations of Glucose, Insulin, and Percent Glycosylated Hemoglobin Are Unaltered by Food Restriction in Rhesus and Squirrel Monkeys

1992 • 40 citations

Locomotor Activity in Female Rhesus Monkeys: Assessment of Age and Calorie Restriction Effects

2000 • 39 citations

Therapeutic controversy: Estrogen replacement in menopause

1996 • 39 citations

Insulin Levels, Physical Activity, and Urinary Catecholamine Excretion of Obese and Non‐Obese Rhesus Monkeys

1993 • 30 citations

Low blood glucose levels and small islets of Langerhans in the pancreas of calorie-restricted mice

1989 • 24 citations

The Androgen Status of Aging Male Rhesus Macaques*

1986 • 23 citations

Effect of Chronic Caloric Restriction on the Circadian Regulation of Physiological and Behavioral Variables in Old Male B6C3F1 Mice

1990 • 19 citations

Dietary Caloric Restriction Prevents the Age-Related Decline in Plasma Melatonin Levels of Rhesus Monkeys

2001 • 19 citations

Evolution of melatonin as a night signal: Contribution from a primitive photosynthetic organism

1992 • 16 citations

Adrenal androgens in insulin-dependent diabetes mellitus.

1989 • 16 citations

Cardiovascular Disease Risk Factors in Males with Normal Body Weight and High Waist-to-Hip Ratio

2001 • 14 citations

Relationships between Reduction in Body Weight and Reduction in Blood Pressure and Improvement of Glucose and Lipid Metabolism Induced by Short-Term Calorie Restriction in Overweight Hypertensive Women

1996 • 6 citations