IL-17B and IL-17C Are Associated with TNF-α Production and Contribute to the Exacerbation of Inflammatory Arthritis

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2001 • 156,143 citations

Transforming growth factor-β induces development of the TH17 lineage

2006 • 3,014 citations

Interleukin-17 Family Members and Inflammation

2004 • 2,340 citations

Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17

2003 • 1,828 citations

BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

2001 • 1,672 citations

Increased expression of interleukin 17 in inflammatory bowel disease

2002 • 1,638 citations

Plat-E: an efficient and stable system for transient packaging of retroviruses

2000 • 1,614 citations

Autoimmunity to type II collagen an experimental model of arthritis.

1977 • 1,599 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

1998 • 954 citations

Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

1999 • 943 citations

Interleukin-17 family and IL-17 receptors

2003 • 905 citations

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

2005 • 844 citations

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

1998 • 810 citations

SECRETION OF PLASMINOGEN ACTIVATOR BY STIMULATED MACROPHAGES

1974 • 719 citations

Treatment with a neutralizing anti‐murine interleukin‐17 antibody after the onset of collagen‐induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

2004 • 698 citations

New IL-17 Family Members Promote Th1 or Th2 Responses in the Lung: In Vivo Function of the Novel Cytokine IL-25

2002 • 611 citations

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

2005 • 598 citations

High Levels of IL-17 in Rheumatoid Arthritis Patients: IL-15 Triggers In Vitro IL-17 Production Via Cyclosporin A-Sensitive Mechanism

2000 • 588 citations

IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding

2001 • 532 citations

IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

2003 • 488 citations

Enhancing Effect of IL-17 on IL-1-Induced IL-6 and Leukemia Inhibitory Factor Production by Rheumatoid Arthritis Synoviocytes and Its Regulation by Th2 Cytokines

1998 • 451 citations

IL-1-Independent Role of IL-17 in Synovial Inflammation and Joint Destruction During Collagen-Induced Arthritis

2001 • 396 citations

Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family

2000 • 343 citations

IL-17 Promotes Bone Erosion in Murine Collagen-Induced Arthritis Through Loss of the Receptor Activator of NF-κB Ligand/Osteoprotegerin Balance

2003 • 342 citations

Cutting Edge: IL-17F, a Novel Cytokine Selectively Expressed in Activated T Cells and Monocytes, Regulates Angiogenesis and Endothelial Cell Cytokine Production

2001 • 340 citations

IL-17 Stimulates Granulopoiesis in Mice: Use of an Alternate, Novel Gene Therapy-Derived Method for In Vivo Evaluation of Cytokines

1998 • 320 citations

Restoration of Tolerance in Lupus by Targeted Inhibitory Receptor Expression

2005 • 261 citations

Interleukin-17 enhances tumor necrosis factor ?-induced synthesis of interleukins 1, 6, and 8 in skin and synovial fibroblasts: A possible role as a ?fine-tuning cytokine? in inflammation processes

2001 • 246 citations

Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum

2006 • 243 citations

A Novel Cytokine Receptor-Ligand Pair

2000 • 223 citations

Nature and specificity of the immune response to collagen in type II collagen-induced arthritis in mice.

1982 • 189 citations

Interleukin‐17 receptor deficiency results in impaired synovial expression of interleukin‐1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall–induced arthritis

2005 • 181 citations

Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis

1999 • 165 citations

Inhibition of Fractalkine Ameliorates Murine Collagen-Induced Arthritis

2004 • 143 citations

Expression of IL-17 Homologs and Their Receptors in the Synovial Cells of Rheumatoid Arthritis Patients

2005 • 141 citations

Interleukin-17 Acts Independently of TNF-α under Arthritic Conditions

2006 • 130 citations

High in vivo expression of interleukin‐17 receptor in synovial endothelial cells and chondrocytes from arthritis patients

2001 • 101 citations

The Effect of a T Cell-Specific NF-κB Inhibitor on In Vitro Cytokine Production and Collagen-Induced Arthritis

2000 • 99 citations

Collagen-induced arthritis development requires αβ T cells but not γδ T cells: studies with T cell-deficient (TCR mutant) mice

1999 • 98 citations

Functional Reconstitution of Class II MHC-Restricted T Cell Immunity Mediated by Retroviral Transfer of the αβ TCR Complex

2000 • 86 citations

Adenoviral Transfer of Cyclin-Dependent Kinase Inhibitor Genes Suppresses Collagen-Induced Arthritis in Mice

2000 • 72 citations

Serum interleukin 17 and interleukin 18 levels in familial Mediterranean fever.

2005 • 51 citations

Circulating interleukin 17 is increased in the acute stage of Kawasaki disease

2003 • 45 citations

Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease

2004 • 38 citations

SPECIES-SPECIFIC EXPRESSION OF TYPE II TGF-β RECEPTOR ISOFORMS BY ARTICULAR CHONDROCYTES: EFFECT OF PROTEOGLYCAN DEPLETION AND AGING

1997 • 13 citations