Inhibition of Fractalkine Ameliorates Murine Collagen-Induced Arthritis

Chemokines

2000 • 3,773 citations

A new class of membrane-bound chemokine with a CX3C motif

1997 • 1,964 citations

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

1998 • 1,943 citations

Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice

1998 • 1,569 citations

Identification and Molecular Characterization of Fractalkine Receptor CX3CR1, which Mediates Both Leukocyte Migration and Adhesion

1997 • 1,406 citations

Macrophages in rheumatoid arthritis.

2000 • 703 citations

Fractalkine and CX3CR1 Mediate a Novel Mechanism of Leukocyte Capture, Firm Adhesion, and Activation under Physiologic Flow

1998 • 679 citations

MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B

1999 • 665 citations

Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation

1997 • 656 citations

A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice.

1998 • 525 citations

Decreased Atherosclerotic Lesion Formation in CX3CR1/Apolipoprotein E Double Knockout Mice

2003 • 465 citations

Stromal Cell-Derived Factor-1-CXC Chemokine Receptor 4 Interactions Play a Central Role in CD4+ T Cell Accumulation in Rheumatoid Arthritis Synovium

2000 • 464 citations

Decreased atherosclerosis in CX3CR1–/– mice reveals a role for fractalkine in atherogenesis

2003 • 460 citations

Chemokines in Immunity

2001 • 431 citations

An Antagonist of Monocyte Chemoattractant Protein 1 (MCP-1) Inhibits Arthritis in the MRL-lpr Mouse Model

1997 • 382 citations

Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice

1999 • 340 citations

Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression

2002 • 320 citations

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses

2001 • 318 citations

Identification of CX 3CR1

1998 • 282 citations

Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis.

1995 • 269 citations

CX₃C Chemokine Fractalkine in Pulmonary Arterial Hypertension

2002 • 269 citations

Chemokines and chemokine receptors in rheumatoid arthritis

2002 • 254 citations

AMD3100, a Potent and Specific Antagonist of the Stromal Cell-Derived Factor-1 Chemokine Receptor CXCR4, Inhibits Autoimmune Joint Inflammation in IFN-γ Receptor-Deficient Mice

2001 • 253 citations

Fractalkine Is an Epithelial and Endothelial Cell-Derived Chemoattractant for Intraepithelial Lymphocytes in the Small Intestinal Mucosa

2000 • 252 citations

Molecular Uncoupling of Fractalkine-mediated Cell Adhesion and Signal Transduction

1999 • 242 citations

Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis

2001 • 236 citations

Fractalkine and fractalkine receptors in human neurons and glial cells

2002 • 226 citations

Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice

1997 • 219 citations

Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis

2003 • 216 citations

Fractalkine-Mediated Endothelial Cell Injury by NK Cells

2000 • 194 citations

Chemokines Regulate IL-6 and IL-8 Production by Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis

2001 • 190 citations

Dual Role of CCR2 during Initiation and Progression of Collagen-Induced Arthritis: Evidence for Regulatory Activity of CCR2+ T Cells

2004 • 183 citations

Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model.

1998 • 182 citations

Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation

1999 • 174 citations

THE ROLE OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) IN THE PATHOGENESIS OF COLLAGEN-INDUCED ARTHRITIS IN RATS

1997 • 172 citations

A Role for Fractalkine and Its Receptor (CX3CR1) in Cardiac Allograft Rejection

2000 • 167 citations

Targeted deletion of CX3CR1 reveals a role for fractalkine in cardiac allograft rejection

2001 • 167 citations

Migration of CX3CR1‐positive T cells producing type 1 cytokines and cytotoxic molecules into the synovium of patients with rheumatoid arthritis

2002 • 155 citations

Targeting the Function of IFN-γ-Inducible Protein 10 Suppresses Ongoing Adjuvant Arthritis

2002 • 130 citations

Experimental arthritis in CC chemokine receptor 2–null mice closely mimics severe human rheumatoid arthritis

2004 • 128 citations

Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8

2001 • 127 citations

A non-peptide CCR5 antagonist inhibits collagen-induced arthritis by modulating T cell migration without affecting anti-collagen T cell responses

2002 • 127 citations

Experimental arthritis in CC chemokine receptor 2–null mice closely mimics severe human rheumatoid arthritis

2004 • 118 citations

Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells

1999 • 109 citations

Proinflammatory role of fractalkine (CX3CL1) in rheumatoid arthritis.

2003 • 99 citations

Rheumatoid arthritis synovial macrophage-osteoclast differentiation is osteoprotegerin ligand-dependent

2000 • 97 citations

Expression of the fractalkine receptor (CX3CR1) in human kidney diseases

2002 • 96 citations

The Role of an Epithelial Neutrophil-Activating Peptide-78-Like Protein in Rat Adjuvant-Induced Arthritis

1999 • 89 citations

Deleted Work

1955 • 0 citations