Betaine Improves the PCR Amplification of GC-Rich DNA Sequences

PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates.

1994 • 1,043 citations

Formamide can dramatically improve the specificity of PCR

1990 • 314 citations

Betaine can eliminate the base pair composition dependence of DNA melting

1993 • 282 citations

PCR bias in amplification of androgen receptor alleles, a trinucleotide repeat marker used in clonality studies

1995 • 193 citations

Alternatively spliced variants of prostate-specific membrane antigen RNA: ratio of expression as a potential measurement of progression.

1995 • 179 citations

Uniform amplification of a mixture of deoxyribonucleic acids with varying GC content.

1996 • 177 citations

A rapid and simple PCR-based method for isolation of cDNAs from differentially expressed genes

1994 • 128 citations

Factors Affecting Fidelity of DNA Synthesis During PCR Amplification of d(C-A)n*d(G-T)n Microsatellite Repeats

1996 • 68 citations

Analysis and Suppression of DNA Polymerase Pauses Associated with a Trinucleotide Consensus

1996 • 62 citations

Optimizing multiplex and LA-PCR with betaine

1997 • 51 citations

PCR-direct sequencing of a GC-rich region by inclusion of 10% DMSO: application to mouse c-jun.

1993 • 46 citations

Use of deoxyinosine in PCR to improve amplification of GC-rich DNA.

1995 • 33 citations

PCR amplification of highly GC-rich DNA template after denaturation by NaOH

1993 • 29 citations