The I Domain is Essential for Echovirus 1 Interaction with VLA-2

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction

2013 • 1,306 citations

Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

1990 • 746 citations

Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.

1987 • 727 citations

The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells.

1990 • 629 citations

The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

1993 • 546 citations

The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.

1989 • 422 citations

A β ₃ Integrin Mutation Abolishes Ligand Binding and Alters Divalent Cation-Dependent Conformation

1990 • 418 citations

Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.

1991 • 401 citations

A novel divalent cation-binding site in the a domain of the ?2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1993 • 383 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit.

1990 • 316 citations

Identification of the Integrin VLA-2 as a Receptor for Echovirus 1

1992 • 310 citations

Distinct cellular functions mediated by different VLA integrin α subunit cytoplasmic domains

1992 • 307 citations

Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins

1989 • 305 citations

Precise gene fusion by PCR

1989 • 292 citations

The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit.

1988 • 238 citations

Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide

1991 • 221 citations

The superfamily of proteins with von Willebrand factor type A-like domains: one theme common to components of extracellular matrix, hemostasis, cellular adhesion, and defense mechanisms

1991 • 206 citations

A discrete sequence in a platelet integrin is involved in ligand recognition

1991 • 204 citations

Integrin (alpha v beta 3)-ligand interaction. Identification of a heterodimeric RGD binding site on the vitronectin receptor.

1990 • 193 citations

Use of the monoclonal antibody 12F1 to characterize the differentiation antigen VLA-2.

1987 • 154 citations

Identification of putative ligand binding sites within I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29)

1994 • 148 citations

Identification of putative ligand binding sites within I domain of integrin α2β1 (VLA-2,CD49b/CD29).

1996 • 136 citations

Regulation of alpha 2 beta 1-mediated fibroblast migration on type I collagen by shifts in the concentrations of extracellular Mg2+ and Ca2+ [published erratum appears in J Cell Biol 1992 Jul;118(1):219]

1992 • 134 citations

Stimulation of tyrosine phosphorylation and accumulation of GTP-bound p21ras upon antibody-mediated alpha 2 beta 1 integrin activation in T-lymphoblastic cells.

1993 • 127 citations

Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin.

1993 • 117 citations

A study of the structure, function and distribution of β5 integrins using novel anti-β5 monoclonal antibodies

1994 • 104 citations

Infection by echoviruses 1 and 8 depends on the alpha 2 subunit of human VLA-2

1993 • 101 citations

The Bra/Brb alloantigen system on human platelets

1989 • 96 citations

The integrin VLA-2 binds echovirus 1 and extracellular matrix ligands by different mechanisms.

1993 • 65 citations

Evidence Against a Major Role for Integrins in Calcium-Dependent Intercellular Adhesion of Epidermal Keratinocytes

1993 • 62 citations

Membrane-associated glycoprotein (gp 160) identified on human lung tumors by a monoclonal antibody.

1986 • 37 citations

Structures and Functions of VLA Proteins and Related Integrins

1991 • 27 citations

The Mouse VLA-2 Homologue Supports Collagen and Laminin Adhesion but Not Virus Binding

1994 • 13 citations