The Gene Search System: A Method for Efficient Detection and Rapid Molecular Identification of Genes in Drosophila melanogaster

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

A stable genomic source of P element transposase in Drosophila melanogaster.

1988 • 1,359 citations

Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector.

1989 • 688 citations

P-element-mediated enhancer detection: a versatile method to study development in Drosophila.

1989 • 679 citations

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes.

1996 • 564 citations

Vectors for Drosophila P-element-mediated transformation and tissue culture transfection

1988 • 547 citations

Insertional Mutagenesis of the Drosophila Genome with Single P Elements

1988 • 533 citations

Gene disruptions using P transposable elements: an integral component of the Drosophila genome project.

1995 • 472 citations

Systematic gain-of-function genetics in Drosophila

1998 • 467 citations

Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

1995 • 460 citations

The Role of the Genome Project in Determining Gene Function: Insights from Model Organisms

1996 • 450 citations

Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.

1988 • 334 citations

The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway

1994 • 315 citations

Preferential transposition of Drosophila P elements to nearby chromosomal sites.

1993 • 253 citations

Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A.

1994 • 195 citations

Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching

1996 • 188 citations

P-Element Insertion Alleles of Essential Genes on the Third Chromosome of Drosophila melanogaster Correlation of Physical and Cytogenetic Maps in Chromosomal Region 86E-87F

1997 • 158 citations

Functional Changes Associated with Structural Alterations Induced by Mobilization of a P Element Inserted in the Sex-lethal Gene of Drosophila

1987 • 143 citations

Gene expression of rat and human microsomal glutathione S-transferases.

1988 • 136 citations

Fasciclin III as a synaptic target recognition molecule in Drosophila

1995 • 134 citations

The Drosophila Roughened mutation: Activation of a rap homolog disrupts eye development and interferes with cell determination

1991 • 123 citations

A molecular evolutionary framework for eukaryotic model organisms

1994 • 112 citations

Inhibition of heat shock protein synthesis by heat-inducible antisense RNA.

1986 • 105 citations

P-Element Insertion Alleles of Essential Genes on the Third Chromosome of Drosophila melanogaster: Mutations Affecting Embryonic PNS Development

1997 • 87 citations

The product of the rap2 gene, member of the ras superfamily

1991 • 39 citations

Biological characterization of Drosophila Rapgap1, a GTPase activating protein for Rap1

1997 • 35 citations

Effects of the ras‐related rap2 protein on cellular proliferation

1991 • 33 citations

Genetic interactions with Rap1 and Ras1 reveal a second function for the Fat facets deubiquitinating enzyme in Drosophila eye development

1997 • 31 citations

Structural Organization of the Human Microsomal GlutathioneS-Transferase Gene (GST12)

1996 • 21 citations

On the specificity of antisense RNA to arrest in vitro translation of mRNA coding for Drosophila hsp 23

1987 • 10 citations