Biological characterization of Drosophila Rapgap1, a GTPase activating protein for Rap1

Antibodies: A laboratory manual

1989 • 4,532 citations

The GTPase superfamily: a conserved switch for diverse cell functions

1990 • 2,330 citations

Identification and characterization of the tuberous sclerosis gene on chromosome 16

1993 • 1,617 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway

1997 • 1,047 citations

A ras-related gene with transformation suppressor activity

1989 • 979 citations

oskar organizes the germ plasm and directs localization of the posterior determinant nanos

1991 • 804 citations

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1995 • 728 citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

1988 • 666 citations

Induction of germ cell formation by oskar

1992 • 643 citations

The product of the Drosophila gene vasa is very similar to eukaryotic initiation factor-4A

1988 • 625 citations

Chapter 24 Imaging Neuronal Subsets and Other Cell Types in Whole-Mount Drosophila Embryos and Larvae Using Antibody Probes

1994 • 608 citations

A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases

1988 • 602 citations

oskar mRNA is localized to the posterior pole of the Drosophila oocyte

1991 • 574 citations

Neuronal differentiation in the Drosophila ommatidium

1987 • 532 citations

Nanos is the localized posterior determinant in Drosophila

1991 • 510 citations

Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development

1991 • 491 citations

Sevenless , a Cell-Specific Homeotic Gene of Drosophila , Encodes a Putative Transmembrane Receptor with a Tyrosine Kinase Domain

1987 • 421 citations

tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster

1985 • 401 citations

Rapid Ca2+-mediated activation of Rap1 in human platelets

1997 • 401 citations

Localization of nanos RNA controls embryonic polarity

1992 • 391 citations

The Drosophila Light-Activated Conductance Is Composed of the Two Channels TRP and TRPL

1996 • 368 citations

Identification of Tuberin, the Tuberous Sclerosis-2 Product. TUBERIN POSSESSES SPECIFIC Rap1GAP ACTIVITY

1995 • 361 citations

RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts.

1993 • 356 citations

Association between GTPase activators for Rho and Ras families

1992 • 322 citations

Arrestin Function in Inactivation of G Protein-Coupled Receptor Rhodopsin in Vivo

1993 • 313 citations

A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase

1992 • 288 citations

Identification of a Novel Human Rho Protein with Unusual Properties: GTPase Deficiency and In Vivo Farnesylation

1996 • 265 citations

Rescue of a Drosophila NF1 Mutant Phenotype by Protein Kinase A

1997 • 254 citations

Preferential transposition of Drosophila P elements to nearby chromosomal sites.

1993 • 253 citations

Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

1991 • 245 citations

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

1990 • 244 citations

GERM CELL DEVELOPMENT IN DROSOPHILA

1996 • 228 citations

Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein

1993 • 224 citations

A role for integrin in the formation of sarcomeric cytoarchitecture

1990 • 207 citations

Differential splicing generates a nervous system—Specific form of drosophila neuroglian

1990 • 165 citations

Involvement of the pumilio gene in the transport of an abdominal signal in the Drosophila embryo

1987 • 145 citations

The Drosophila Roughened mutation: Activation of a rap homolog disrupts eye development and interferes with cell determination

1991 • 123 citations

Co-localization of the TSC2 product tuberin with its target Rap1 in the Golgi apparatus.

1996 • 109 citations

Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes.

1994 • 96 citations

Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis.

1992 • 57 citations

An inverse PCR screen for the detection of P element insertions in cloned genomic intervals in Drosophila melanogaster.

1995 • 49 citations

Constructing deletions with defined endpoints in Drosophila.

1990 • 43 citations

Expression of ras cellular oncogenes during development of Drosophila melanogaster.

1985 • 30 citations

Localization of the raplGAP Catalytic Domain and Sites of Phosphorylation by Mutational Analysis

1992 • 11 citations

Expression of ras Cellular Oncogenes During Development of Drosophila melanogaster

1985 • 6 citations