Δ12-Prostaglandin J2, a Plasma Metabolite of Prostaglandin D2, Causes Eosinophil Mobilization from the Bone Marrow and Primes Eosinophils for Chemotaxis

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

1994 • 3,249 citations

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1998 • 3,026 citations

Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

2001 • 1,072 citations

Prostaglandin D ₂ as a Mediator of Allergic Asthma

2000 • 731 citations

Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin

1997 • 482 citations

Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.

1983 • 334 citations

Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor

2001 • 328 citations

Eotaxin Induces a Rapid Release of Eosinophils and Their Progenitors From the Bone Marrow

1998 • 283 citations

Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases

2000 • 280 citations

Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP

2001 • 241 citations

Basophils in bronchial asthma with reference to reagin‐type allergy

1973 • 237 citations

Modulation and induction of eosinophil chemotaxis by granulocyte- macrophage colony-stimulating factor and interleukin-3

1991 • 230 citations

Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects

1992 • 226 citations

Pronounced Eosinophilic Lung Inflammation and Th2 Cytokine Release in Human Lipocalin-Type Prostaglandin D Synthase Transgenic Mice

2002 • 225 citations

Mechanisms of Acute Eosinophil Mobilization from the Bone Marrow Stimulated by Interleukin 5: The Role of Specific Adhesion Molecules and Phosphatidylinositol 3-Kinase

1998 • 204 citations

Human eotaxin represents a potent activator of the respiratory burst of human eosinophils

1996 • 171 citations

Mast cells, basophils, and eosinophils: distinct but overlapping pathways for recruitment

2001 • 169 citations

9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma.

1984 • 160 citations

Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine.

1988 • 149 citations

Prostaglandin J2--anti-tumour and anti-viral activities and the mechanisms involved.

1990 • 145 citations

Chemokines, Chemokine Receptors and Allergy

2001 • 137 citations

15-Deoxy-Δ12,1412,14-prostaglandins D2 and J2 Are Potent Activators of Human Eosinophils

2002 • 112 citations

Role of human basophils and mast cells in the pathogenesis of allergic diseases

1985 • 108 citations

The Role of p38 MAP Kinase in TGF-β1-Induced Signal Transduction in Human Neutrophils

1998 • 107 citations

Eotaxin and asthma

2001 • 101 citations

Translocation of the tetraspanin CD63 in association with human eosinophil mediator release

2002 • 95 citations

Chemokines and chemokine receptors: their role in allergic airway disease.

1999 • 86 citations

Basophil Responses to Chemokines Are Regulated by Both Sequential and Cooperative Receptor Signaling

2000 • 78 citations

Indomethacin Causes Prostaglandin D2-like and Eotaxin-like Selective Responses in Eosinophils and Basophils

2002 • 76 citations

Eotaxin Induces a Rapid Release of Eosinophils and Their Progenitors From the Bone Marrow

1998 • 68 citations

A surrogate method for assessment of β2-integrin-dependent adhesion of human eosinophils to ICAM-1

2000 • 57 citations

Human Eosinophils Constitutively Express a Functional Interleukin-4 Receptor: Interleukin-4 –Induced Priming of Chemotactic Responses and Induction of PI-3 Kinase Activity

1998 • 47 citations

Transport of prostaglandin D2 into brain

1986 • 40 citations

9-Deoxy-Δ9,Δ12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma

1984 • 26 citations