Human eotaxin represents a potent activator of the respiratory burst of human eosinophils

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

1989 • 1,993 citations

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.

1994 • 822 citations

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.

1996 • 719 citations

Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia

1996 • 698 citations

Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils.

1992 • 683 citations

The Immunobiology of Eosinophils

1991 • 660 citations

Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo.

1995 • 657 citations

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes.

1992 • 620 citations

Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

1995 • 555 citations

Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.

1987 • 542 citations

CC chemokines in allergic inflammation

1994 • 540 citations

Extension of Recombinant Human RANTES by the Retention of the Initiating Methionine Produces a Potent Antagonist

1996 • 424 citations

Molecular Cloning of Human Eotaxin, an Eosinophil-selective CC Chemokine, and Identification of a Specific Eosinophil Eotaxin Receptor, CC Chemokine Receptor 3

1996 • 412 citations

Structure-activity relationships of chemokines

1995 • 367 citations

Chemotactic peptide modulation of actin assembly and locomotion in neutrophils.

1984 • 359 citations

RANTES is a chemotactic and activating factor for human eosinophils.

1993 • 355 citations

Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression.

1995 • 351 citations

Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine.

1994 • 342 citations

A Ca2+-insensitive form of fura-2 associated with polymorphonuclear leukocytes. Assessment and accurate Ca2+ measurement.

1987 • 317 citations

Neutrophil-activating properties of the melanoma growth-stimulatory activity.

1990 • 277 citations

Cloning and Functional Expression of a Human Eosinophil CC Chemokine Receptor

1995 • 246 citations

Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes.

1994 • 212 citations

Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung.

1995 • 204 citations

The role of eosinophils in the pathogenesis of atopic dermatitis ‐ eosinophil granule proteins as markers of disease activity

1993 • 179 citations

Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1 alpha, or human interleukin 8.

1993 • 171 citations

C3a activates reactive oxygen radical species production and intracellular calcium transients in human eosinophils

1994 • 168 citations

Eotaxin: Cloning of an Eosinophil Chemoattractant Cytokine and Increased mRNA Expression in Allergen-Challenged Guinea-Pig Lungs

1994 • 156 citations

C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins

1994 • 154 citations

The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: relationship to eosinophil, T cell, and macrophage recruitment.

1995 • 145 citations

Lipopolysaccharide-stimulated human monocytes secrete, apart from neutrophil-activating peptide 1/interleukin 8, a second neutrophil-activating protein. NH2-terminal amino acid sequence identity with melanoma growth stimulatory activity.

1990 • 142 citations

Eosinophil adhesion to vascular cell adhesion molecule-1 activates superoxide anion generation.

1995 • 122 citations

Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils.

1991 • 121 citations

Monocyte chemotactic protein MCP-2 activates human basophil and eosinophil leukocytes similar to MCP-3.

1995 • 107 citations

The Chemokine RANTES Is More than a Chemoattractant: Characterization of Its Effect on Human Eosinophil Oxidative Metabolism and Morphology in Comparison with IL-5 and GM-CSF

1994 • 106 citations

5-Oxo-eicosanoids Are Potent Eosinophil Chemotactic Factors.

1995 • 91 citations

Role of the A subunit of pertussis toxin in alteration of Chinese hamster ovary cell morphology

1987 • 86 citations

Characterization and species distribution of high affinity GTP-coupled receptors for human rantes and monocyte chemoattractant protein 1.

1993 • 84 citations

Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid.

1992 • 81 citations

Mechanisms of human eosinophil activation by complement protein C5a and platelet‐activating factor: similar functional responses are accompanied by different morphologic alterations

1995 • 60 citations

Actin polymerization in human eosinophils, unlike human neutrophils, depends on intracellular calcium mobilization

1996 • 47 citations

Actin polymerization in human eosinophils, unlike human neutrophils, depends on intracellular calcium mobilization

1996 • 40 citations

Activation of the Respiratory Burst in Human Eosinophils by Chemotaxins Requires Intracellular Calcium Fluxes

1995 • 34 citations

Human neutrophil (PMN) oxygen radical production and the cytoskeleton

1995 • 21 citations

Flow cytometry reveals different lag times in rapid cytoplasmic calcium elevations in human neutrophils in response to N‐formyl peptide

1993 • 15 citations

Mechanisms of epithelial damage: are there parallels between bullous skin diseases and asthma?

1994 • 6 citations