Multiple Differences in Agonist and Antagonist Pharmacology between Human and Guinea Pig Histamine H₁-Receptor

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The classification of seven transmembrane receptors in recombinant expression systems.

1996 • 271 citations

Histamine H₁-Receptor Activation of Nuclear Factor-κB: Roles for Gβγ- and Gα_q/11-Subunits in Constitutive and Agonist-Mediated Signaling

2001 • 253 citations

Partial agonists, full agonists, antagonists: dilemmas of definition

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HETEROGENEITY OF HISTAMINE Hi‐RECEPTORS: SPECIES VARIATIONS IN [³H]MEPYRAMINE BINDING OF BRAIN MEMBRANES

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Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.

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Molecular Cloning of the Human Histamine H1 Receptor Gene

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Site-Directed Mutagenesis of the Histamine H1 Receptor: Roles of Aspartic Acid107, Asparagine198 and Threonine194

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Site-Directed Mutagenesis of the Histamine H1-Receptor Reveals a Selective Interaction of Asparagine207 with Subclasses of H1-Receptor Agonists

1994 • 78 citations

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Distinct Interaction of Human and Guinea Pig Histamine H₂-Receptor with Guanidine-Type Agonists

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Synthesis and Histamine H1 Receptor Agonist Activity of a Series of 2-Phenylhistamines, 2-Heteroarylhistamines, and Analogs

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Unique binding pocket for KW-4679 in the histamine H1 receptor

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Oligomer formation of histamine H2 receptors expressed in Sf9 and COS7 cells¹

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The human histamine H₂‐receptor couples more efficiently to Sf9 insect cell G_s‐proteins than to insect cell G_q‐proteins: limitations of Sf9 cells for the analysis of receptor/G_q‐protein coupling

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Defective Gi Protein Coupling in Two Formyl Peptide Receptor Mutants Associated with Localized Juvenile Periodontitis

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Lysine200 Located in the Fifth Transmembrane Domain of the Histamine H1 Receptor Interacts with Histamine but Not with All H1 Agonists

1995 • 49 citations

The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.

1994 • 44 citations

Histamine analogues. 33rd communication: 2-phenylhistamines with high histamine H1-agonistic activity

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The (S)-(+)-enantiomer of dimethindene: a novel M2-selective muscarinic receptor antagonist

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Photoaffinity Labeling and Electrophoretic Identification of the H₁‐Receptor: Comparison of Several Brain Regions and Animal Species

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Developments in histamine H1-receptor agonists

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Receptor glycosylation regulates the affinity of histamine H1 receptors during smooth muscle cell differentiation.

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