PD-L1 partially protects renal tubular epithelial cells from the attack of CD8+cytotoxic T cells

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

2002 • 4,625 citations

Restoring function in exhausted CD8 T cells during chronic viral infection

2005 • 3,743 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

1999 • 2,574 citations

THE B7 FAMILY REVISITED

2005 • 2,239 citations

The B7–CD28 superfamily

2002 • 1,646 citations

TNF/TNFR FAMILY MEMBERS IN COSTIMULATION OF T CELL RESPONSES

2004 • 1,320 citations

Co-inhibitory molecules of the B7–CD28 family in the control of T-cell immunity

2004 • 1,213 citations

Tissue expression of PD-L1 mediates peripheral T cell tolerance

2006 • 1,145 citations

Blockade of B7-H1 and PD-1 by Monoclonal Antibodies Potentiates Cancer Therapeutic Immunity

2005 • 972 citations

Blockade of Programmed Death-1 Ligands on Dendritic Cells Enhances T Cell Activation and Cytokine Production

2003 • 933 citations

The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice

2003 • 766 citations

Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target

2004 • 742 citations

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

2004 • 609 citations

Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responses

2003 • 594 citations

Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy

2004 • 571 citations

Critical Role of the Programmed Death-1 (PD-1) Pathway in Regulation of Experimental Autoimmune Encephalomyelitis

2003 • 486 citations

A critical role for the programmed death ligand 1 in fetomaternal tolerance

2005 • 402 citations

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon.

1987 • 396 citations

Expression of the B7 - related molecule B7 - H1 by glioma cells: a potential mechanism of immune paralysis

2003 • 370 citations

618: Costimulatory B7-H1 In Renal Cell Carcinoma Patients: Indicator of Tumor Aggressiveness and Potential Therapeutic Target

2005 • 358 citations

Interferon-β enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis

2004 • 269 citations

MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells

1990 • 246 citations

Differential mechanisms of action of interferon-β and glatiramer acetate in MS

2002 • 238 citations

BK virus nephritis after renal transplantation

2006 • 209 citations

Role of the Programmed Death-1 Pathway in Regulation of Alloimmune Responses In Vivo

2005 • 177 citations

In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis

2004 • 162 citations

Stimulating PD-1???negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival1

2003 • 151 citations

Interferon-γ is required for lupus nephritis in mice treated with the hydrocarbon oil pristane

2001 • 111 citations

Suppressed T-cell activation by IFN- -induced expression of PD-L1 on renal tubular epithelial cells

2004 • 101 citations

PD-L1 is expressed by human renal tubular epithelial cells and suppresses T cell cytokine synthesis

2005 • 96 citations

Blockade of the Interaction Between PD-1 and PD-L1 Accelerates Graft Arterial Disease in Cardiac Allografts

2004 • 89 citations

Epstein-Barr virus infection of renal proximal tubule cells: possible role in chronic interstitial nephritis

1999 • 80 citations

Tubular Epithelial Cells: A Critical Cell Type in the Regulation of Renal Inflammatory Processes

1999 • 75 citations

Experimental Autoimmune Anti–Glomerular Basement Membrane Glomerulonephritis

2004 • 69 citations

Role of CD8+ cells in the progression of murine adriamycin nephropathy

2001 • 67 citations

Interferon-β

2005 • 67 citations

Interferon Beta in Multiple Sclerosis

1996 • 63 citations

Renal tubular epithelial cells modulate T-cell responses via ICOS-L and B7-H1

2005 • 52 citations

Critical Role for CD103+CD8+ Effectors in Promoting Tubular Injury following Allogeneic Renal Transplantation

2005 • 50 citations

Enhanced tubular epithelial CD44 expression in MRL-lpr lupus nephritis

1996 • 49 citations

Effector mechanisms in organ-specific autoimmunity. I. Characterization of a CD8+ T cell line that mediates murine interstitial nephritis.

1991 • 48 citations

Expression of B7-H1 in Inflammatory Renal Tubular Epithelial Cells

2005 • 41 citations

Upregulation of lymphoid and renal interferon-gamma mRNA in autoimmune MRL-Fas(lpr) mice with lupus nephritis.

1997 • 30 citations

The nephritogenic T lymphocyte response in interstitial nephritis.

1993 • 13 citations

CD8+ Lymphocytes Play a Central Role in the Development of Anti-GBM Nephritis through Induction of ICAM-I and Chemokines in WKY Rats

2015 • 8 citations

Autoimmune Tubulointerstitial Nephritis: Insight from Experimental Models

1998 • 5 citations

353. In a Model of Tumor Dormancy, Long-Term Persistent Leukemic Cells Have Increased B7-H1 and B7.1 Expression and Resist CTL-Mediated Lysis

2004 • 5 citations