MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

HISTOCHEMICAL AND ULTRASTRUCTURAL DEMONSTRATION OF γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY

1969 • 940 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

The origin and characteristics of a pig kidney cell strain, LLC-PK1

1976 • 604 citations

Warner-Lambert/Parke-Davis award lecture. Cytokine-mediated activation of vascular endothelium. Physiology and pathology.

1988 • 597 citations

Evidence for function of Ia molecules on gut epithelial cells in man.

1987 • 521 citations

Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses.

1988 • 441 citations

Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells

1984 • 432 citations

Widespread and selective induction of major histocompatibility complex-determined antigens in vivo by gamma interferon.

1985 • 397 citations

Human vascular smooth muscle cells. Target for and source of tumor necrosis factor.

1989 • 333 citations

Increased tumor necrosis factor and IL-1 beta gene expression in the kidneys of mice with lupus nephritis.

1988 • 321 citations

Epidermal Cell Production of Thymocyte Activating Factor (ETAF)

1982 • 319 citations

Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis.

1988 • 311 citations

cDNA cloning of murine interleukin-HP1: homology with human interleukin 6

1988 • 292 citations

Quantitative variation in la antigen expression plays a central role in immune regulation

1984 • 270 citations

Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1 beta.

1986 • 267 citations

Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression

1985 • 266 citations

Inducible interleukin-1 gene expression in human vascular smooth muscle cells.

1986 • 256 citations

Antigen presenting function of class II MHC expressing pancreatic beta cells

1988 • 255 citations

Class II MHC-bearing keratinocytes induce antigen-specific unresponsiveness in hapten-specific Th1 clones.

1988 • 241 citations

Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide

1989 • 220 citations

Expression of early genes of origin-defective mutants of simian virus 40.

1980 • 205 citations

Effects of interferon-gamma and tumor necrosis factor-alpha on the expression of an Ia antigen on a murine macrophage cell line.

1986 • 199 citations

Origin-defective Mutants of SV40

1980 • 193 citations

Epidermal growth factor, its receptor, and related proteins

1986 • 186 citations

EGF-induced mitogenesis in proximal tubular cells: potentiation by angiotensin II

1987 • 182 citations

Interleukin 1 and the glomerular mesangium. I. Purification and characterization of a mesangial cell-derived autogrowth factor.

1986 • 164 citations

The interleukin 1 gene is expressed by rat glomerular mesangial cells and is augmented in immune complex glomerulonephritis.

1987 • 159 citations

Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts.

1986 • 159 citations

Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event.

1981 • 153 citations

Novel and enhanced IL-1 gene expression in autoimmune mice with lupus.

1988 • 126 citations

Enhanced transformation of human fibroblasts by origin-defective simian virus 40

1982 • 123 citations

B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene.

1988 • 118 citations

Induction of HLA class II genes by IFN-gamma is transcriptional and requires a trans-acting protein.

1989 • 113 citations

Increased renal thromboxane production in murine lupus nephritis.

1986 • 106 citations

Transport and metabolism of glucose by renal proximal tubular cells in primary culture

1984 • 103 citations

Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line.

1988 • 101 citations

Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MRL/lpr mice with lupus nephritis.

1989 • 100 citations

Class II histocompatibility antigen-mediated immunologic function of normal articular chondrocytes.

1985 • 85 citations

Induction of IA antigens in murine renal transplants.

1985 • 84 citations

Direct evidence that a class II molecule and a simple globular protein generate multiple determinants.

1985 • 84 citations

EXPRESSION OF HLA ANTIGENS ON RENAL TUBULAR CELLS IN CULTURE II. EFFECT OF INCREASED HLA ANTIGEN EXPRESSION ON TUBULAR CELL STIMULATION OF LYMPHOCYTE ACTIVATION AND ON THEIR VULNERABILITY TO CELL-MEDIATED LYSIS

1988 • 71 citations

EXPRESSION OF HLA ANTIGENS ON RENAL TUBULAR CELLS IN CULTURE

1986 • 61 citations

The generation of human monocyte/macrophage cell lines

1983 • 58 citations

Induction of macrophage Ia antigen expression by rIFN-gamma and down-regulation by IFN-alpha/beta and dexamethasone are regulated transcriptionally.

1988 • 57 citations

Interferon gamma regulates binding of two nuclear protein complexes in a macrophage cell line.

1990 • 43 citations

Cloning of human thymic subcapsular cortex epithelial cells with T-lymphocyte binding sites and hemopoietic growth factor activity.

1987 • 39 citations

DNA-mediated transfer of major histocompatibility class II I-Ab and I-Abm12 genes into B lymphoma cells: molecular and functional analysis of introduced antigens.

1985 • 37 citations

Release of cAMP from a renal epithelial cell line

1984 • 36 citations

Use of monoclonal antibodies to culture rat proximal tubule cells

1986 • 32 citations

Graft-vs-host reactions induce H-2 class II gene transcription in host kidney cells

1984 • 29 citations

Cycloheximide, an inhibitor of protein synthesis, prevents ?-interferon-induced expression of class II mRNA in a macrophage cell line

1988 • 26 citations

Characterization and antigen-presenting function of a murine thyroid-derived epithelial cell line.

1987 • 24 citations

Corticosteroid induction of Ig+Ia- B cells in vitro is mediated via interaction with the glucocorticoid cytoplasmic receptor.

1988 • 24 citations

B-cell-specific and interferon-γ-inducible regulation of the HLA-DRa gene. Proc

1988 • 16 citations

Transformation of human kidney proximal tubule cells by ras-containing retroviruses. Implications for tumor progression.

1989 • 15 citations

Regulation of HLA Antigen Expression in Human Kidney

1986 • 14 citations

THE EFFECT OF STEROIDS ON THE REGULATION OF MAJOR NONLYMPHOID TISSUE1 HISTOCOMPATIBILITY COMPLEX-CLASS I1 EXPRESSION ON

1989 • 9 citations