Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp 2H) mutant

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

PCR protocols — A guide to methods and applications

1990 • 10,078 citations

Retinoic Acid Embryopathy

1985 • 1,921 citations

Neural Crest Cells Contribute to Normal Aorticopulmonary Septation

1983 • 1,083 citations

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

1994 • 987 citations

Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

1991 • 897 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

The Migration and Differentiation of Neural Crest Cells

1970 • 814 citations

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1994 • 777 citations

Comparison of three actin-coding sequences in the mouse; Evolutionary relationships between the actin genes of warm-blooded vertebrates

1986 • 678 citations

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

1991 • 664 citations

Segmental origin and migration of neural crest cells in the hindbrain region of the chick embryo

1991 • 635 citations

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.

1994 • 634 citations

Retinoic acid receptors and cellular retinoid binding proteins : II. Their differential pattern of transcription during early morphogenesis in mouse embryos

1991 • 527 citations

Neural Crest and Cardiovascular Patterning

1995 • 523 citations

Morphogenesis of malformations in hamsters caused by retinoic acid: Relation to dose and stage at treatment

1972 • 501 citations

Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells

1994 • 495 citations

Regulation of Pax-3 expression in the dermomyotome and its role in muscle development

1994 • 491 citations

Vital dye analysis of cranial neural crest cell migration in the mouse embryo

1992 • 470 citations

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4

1996 • 464 citations

Dependence of Thymus Development on Derivatives of the Neural Crest

1984 • 463 citations

The role of Hoxa-3 in mouse thymus and thyroid development

1995 • 421 citations

Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.

1995 • 393 citations

Role of neural crest in congenital heart disease.

1990 • 390 citations

Analysis of the developmental effects of a lethal mutation in the house mouse

1954 • 290 citations

The met Proto-Oncogene Receptor and Lumen Formation

1992 • 246 citations

Loss of p53 function through PAX-mediated transcriptional repression.

1995 • 236 citations

Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse

1996 • 215 citations

The Splotch mutation interferes with muscle development in the limbs

1993 • 205 citations

PAX genes

1994 • 190 citations

Persistent truncus arteriosus in the Splotch mutant mouse

1989 • 184 citations

A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant.

1993 • 180 citations

Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages.

1988 • 172 citations

Pax3: A paired domain gene as a regulator in PNS myelination

1995 • 161 citations

Cloning a balanced translocation associated with DiGeorge syndrome and identification of a disrupted candidate gene

1995 • 159 citations

Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain

1995 • 146 citations

Expression of the met receptor tyrosine kinase in muscle progenitor cells in somites and limbs is absent in Splotch mice

1996 • 140 citations

Isolation of a putative transcriptional regulator from the region of 22q11 deleted in DiGeorge syndrome, Shprintzen syndrome and familial congenital heart disease

1993 • 140 citations

Homoeobox gene expression in mouse embryos varies with position by the primitive streak stage

1986 • 126 citations

Analysis of the Pax-3 Gene in the Mouse Mutant Splotch

1993 • 125 citations

Mouse cellular retinoic acid binding protein: cloning, complementary DNA sequence, and messenger RNA expression during the retinoic acid-induced differentiation of F9 wild type and RA-3-10 mutant teratocarcinoma cells.

1989 • 122 citations

Migration of cranial neural crest cells to the pharyngeal arches and heart in rat embryos

1992 • 120 citations

Co-expression of theHGF/SF andc-met genes during early mouse embryogenesis precedes reciprocal expression in adjacent tissues during organogenesis

1996 • 115 citations

Molecular basis of splotch and Waardenburg Pax-3 mutations.

1994 • 114 citations

The Splotch-Delayed (Spd) Mouse Mutant Carries a Point Mutation within the Paired Box of the Pax-3 Gene

1993 • 112 citations

Y353/B: a candidate multiple-copy spermiogenesis gene on the mouse Y chromosome

1994 • 105 citations

Platelet‐derived growth factor receptor alpha subunit deleted Patch mouse exhibits severe cardiovascular dysmorphogenesis

1995 • 98 citations

Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5.

1991 • 84 citations

Delayed neural crest cell emigration from Sp and Sp^d mouse neural tube explants

1990 • 79 citations

Normal stages of cardiac organogenesis in the mouse: I. Development of the external shape of the heart

1989 • 79 citations

Non-overlapping expression of CRBP I and CRABP I during pattern formation of limbs and craniofacial structures in the early mouse embryo

1993 • 71 citations

Dissection and culture of postimplantation Embryos

1990 • 68 citations

Defective Ensheathment of Motoric Nerves in the Splotch Mutant Mouse

1990 • 65 citations

Developmental control of N-CAM expression by Hox and Pax gene products

1995 • 60 citations

Anteriorization of CRABP-I Expression by Retinoic Acid in the Developing Mouse Central Nervous System and Its Relationship to Teratogenesis

1995 • 54 citations

The Splotch (Sp1H) and Splotch-delayed (Spd) alleles: differential phenotypic effects on neural crest and limb musculature

1993 • 53 citations

The differentiation in vitro of the neural crest cells of the mouse embryo

1984 • 50 citations

Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome

1993 • 49 citations

Interaction between splotch (Sp) and curly tail (ct) mouse mutants in the embryonic development of neural tube defects

1993 • 48 citations

Genomic Organization and Chromosome Localization of the Murine Homeobox Gene Pmx

1994 • 38 citations

Deletions of human chromosome 22 and associated birth defects

1993 • 31 citations

Observations on the development of the aortico-pulmonary spiral septum in the mouse.

1988 • 22 citations

Early development of macrophages in intact and organ cultured hearts of rat embryos

1994 • 15 citations

Differential expression of RAR-� and RXR-? transcripts in cultured cranial neural crest cells

1994 • 7 citations