Developmental control of N-CAM expression by Hox and Pax gene products

Cell Adhesion Molecules

1983 • 1,017 citations

CELL ADHESION MOLECULES: Implications for a Molecular Histology

1991 • 707 citations

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

1991 • 664 citations

Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila

1986 • 497 citations

Hox and HOM: Homologous gene clusters in insects and vertebrates

1989 • 467 citations

Segmental organization of embryonic diencephalon

1993 • 395 citations

Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes.

1994 • 364 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 356 citations

The paired box encodes a second DNA-binding domain in the paired homeo domain protein.

1991 • 349 citations

A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells

1993 • 309 citations

The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype

1993 • 290 citations

The molecular basis of the undulated/Pax-1 mutation

1991 • 273 citations

Cell adhesion molecules as targets for Hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4.

1992 • 215 citations

Zebrafish pax[zf-a]: a paired box-containing gene expressed in the neural tube.

1991 • 213 citations

Conservation of the paired domain in metazoans and its structure in three isolated human genes.

1989 • 210 citations

Defects of neuronal migration and the pathogenesis of cortical malformations are associated with Small eye (Sey) in the mouse, a point mutation at the Pax-6-locus

1993 • 200 citations

Pax: Gene regulators in the developing nervous system

1993 • 195 citations

Expression sequences of cell adhesion molecules.

1985 • 193 citations

A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant.

1993 • 180 citations

N-CAM at the vertebrate neuromuscular junction.

1985 • 179 citations

Differential distribution of cell adhesion molecules during histogenesis of the chick nervous system

1986 • 179 citations

Pax-3 contains domains for transcription activation and transcription inhibition.

1994 • 132 citations

Molecular basis of splotch and Waardenburg Pax-3 mutations.

1994 • 114 citations

Outside and downstream of the homeobox.

1993 • 101 citations

Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HoxC6 (Hox-3.3).

1993 • 100 citations

The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution

1991 • 93 citations

Distribution and role in regeneration of N-CAM in the basal laminae of muscle and Schwann cells.

1988 • 90 citations

Regulation in vitro of an L-CAM enhancer by homeobox genes HoxD9 and HNF-1.

1994 • 70 citations

Alterations in the Xenopus retinotectal projection by antibodies to Xenopus N-CAM

1988 • 60 citations

Binding and activation of the promoter for the neural cell adhesion molecule by Pax-8.

1994 • 43 citations

Localization of mRNA for neural cell adhesion molecule (N-CAM) polypeptides in neural and nonneural tissues by in situ hybridization.

1989 • 39 citations

Identification of the promoter and a transcriptional enhancer of the gene encoding L-CAM, a calcium-dependent cell adhesion molecule.

1993 • 23 citations