Discovery of estrogen receptor α target genes and response elements in breast tumor cells

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

2001 • 10,602 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

Initial sequencing and comparative analysis of the mouse genome

2002 • 6,971 citations

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

2003 • 2,013 citations

Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

1997 • 1,808 citations

Identifying differentially expressed genes using false discovery rate controlling procedures

2003 • 1,741 citations

"Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells

2002 • 1,721 citations

Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription

2000 • 1,658 citations

A Stem Cell Molecular Signature

2002 • 1,553 citations

Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators

2002 • 1,449 citations

Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

2003 • 1,422 citations

Predicting the clinical status of human breast cancer by using gene expression profiles

2001 • 1,336 citations

Estrogen receptor interaction with estrogen response elements

2001 • 1,031 citations

RefSeq and LocusLink: NCBI gene-centered resources

2001 • 899 citations

Profiling of Estrogen Up- and Down-Regulated Gene Expression in Human Breast Cancer Cells: Insights into Gene Networks and Pathways Underlying Estrogenic Control of Proliferation and Cell Phenotype

2003 • 868 citations

Estrogen receptor pathways to AP-1

2000 • 867 citations

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

1995 • 756 citations

Cyclic, Proteasome-Mediated Turnover of Unliganded and Liganded ERα on Responsive Promoters Is an Integral Feature of Estrogen Signaling

2003 • 718 citations

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns.

2001 • 672 citations

Establishment and characterization of a cell line of human breast carcinoma origin

1979 • 653 citations

Analysis of Chromatin Structure byin VivoFormaldehyde Cross-Linking

1997 • 610 citations

Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor

1997 • 399 citations

Ligand-, Cell-, and Estrogen Receptor Subtype (α/β)-dependent Activation at GC-rich (Sp1) Promoter Elements

2000 • 393 citations

17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells.

1996 • 344 citations

Genome-Wide Identification of High-Affinity Estrogen Response Elements in Human and Mouse

2004 • 334 citations

The Stanford Microarray Database: data access and quality assessment tools

2003 • 332 citations

Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms

1999 • 312 citations

Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7

1984 • 304 citations

Estrogen receptor alpha in human breast cancer: occurrence and significance.

2000 • 302 citations

Development of cDNA microarray for expression profiling of estrogen-responsive genes

2002 • 293 citations

Stimulation of c-myc oncogene expression associated with estrogen-induced proliferation of human breast cancer cells.

1987 • 282 citations

ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells¹

2001 • 260 citations

Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray

2003 • 243 citations

PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer.

2000 • 242 citations

MGD: the Mouse Genome Database

2003 • 240 citations

Estrogens in the causation of breast, endometrial and ovarian cancers — evidence and hypotheses from epidemiological findings

2000 • 236 citations

Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells.

1996 • 233 citations

Identification of a New Subclass of Alu DNA Repeats Which Can Function as Estrogen Receptor-dependent Transcriptional Enhancers

1995 • 226 citations

A Regulatory Role for RIP140 in Nuclear Receptor Activation

1998 • 222 citations

Estrogen Regulation of Cyclin D1 Gene Expression in ZR-75 Breast Cancer Cells Involves Multiple Enhancer Elements

2001 • 200 citations

Diversity in the mechanisms of gene regulation by estrogen receptors

2002 • 193 citations

RERG Is a Novel ras-related, Estrogen-regulated and Growth-inhibitory Gene in Breast Cancer

2001 • 168 citations

Identification of Estrogen-Responsive Genes by Complementary Deoxyribonucleic Acid Microarray and Characterization of a Novel Early Estrogen-Induced Gene:EEIG1

2003 • 136 citations

Estrogen Receptor α and Activating Protein-1 Mediate Estrogen Responsiveness of the Progesterone Receptor Gene in MCF-7 Breast Cancer Cells

2002 • 129 citations

Dragon ERE Finder version 2: a tool for accurate detection and analysis of estrogen response elements in vertebrate genomes

2003 • 122 citations

Identification of novel oestrogen receptor target genes in human ZR75-1 breast cancer cells by expression profiling

2001 • 113 citations

Receptor Interacting Protein RIP140 Inhibits Both Positive and Negative Gene Regulation by Glucocorticoids

1999 • 100 citations

The 52-kDa estrogen-induced protein secreted by MCF7 cells is a lysosomal acidic protease

1986 • 98 citations

Estrogen Receptor Action

2002 • 97 citations

The gene expression response of breast cancer to growth regulators: patterns and correlation with tumor expression profiles.

2003 • 96 citations

Update on animal models developed for analyses of estrogen receptor biological activity

2003 • 92 citations

Estrogen Receptor/Sp1 Complexes Are Required for Induction ofcadGene Expression by 17β-Estradiol in Breast Cancer Cells

2003 • 92 citations

Estrogen Stimulates Estrogen-Related Receptor α Gene Expression through Conserved Hormone Response Elements

2003 • 92 citations

Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells

1996 • 88 citations

Regulation of DNA Replication Fork Genes by 17β-Estradiol

2002 • 73 citations

Cyclin D1 and estrogen receptor messenger RNA levels are positively correlated in primary breast cancer.

1996 • 71 citations

Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α

1998 • 69 citations

Transcriptional Activation of the Nuclear Receptor Corepressor RIP140 by Retinoic Acid: A Potential Negative-Feedback Regulatory Mechanism

2001 • 65 citations

Characterization of androgen receptor and nuclear receptor co‐regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3

2002 • 56 citations

Effects of 17 beta-estradiol on progesterone receptors and the uptake of thymidine in human breast cancer cell line CAMA-1.

1981 • 43 citations

Transcriptional activation of rat creatine kinase B by 17β‐estradiol in MCF‐7 cells involves an estrogen responsive element and GC‐rich sites

2001 • 28 citations

Regulation of DNA Replication Fork Genes by 17 -Estradiol

2002 • 25 citations

Analysis of Chromatin Structurein Vivo

1997 • 24 citations

Hormone-sensitive gene expression in breast tumours.

1990 • 11 citations